rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q92EK7 | 248 | Y452_LISIN Uncharacterized oxidoreductase Lin... | 185 | 0.00000001 | 58.9 | 28 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 32 | Q9GKX2 | 260 | DHRS4_RABIT Dehydrogenase/reductase SDR famil... | 208 | 0.00000001 | 58.9 | 26 | 46 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 33 | Q9WVK3 | 303 | PECR_RAT Peroxisomal trans-2-enoyl-CoA reduct... | 225 | 0.00000001 | 58.9 | 25 | 42 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 34 | Q5HLD8 | 230 | Y2049_STAEQ Uncharacterized oxidoreductase SE... | 217 | 0.00000003 | 57.4 | 24 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 35 | Q8CN40 | 230 | Y2036_STAES Uncharacterized oxidoreductase SE... | 217 | 0.00000003 | 57.4 | 24 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 36 | Q5R6U1 | 325 | DRS7B_PONAB Dehydrogenase/reductase SDR famil... | 234 | 0.00000006 | 57 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 37 | Q6IAN0 | 325 | DRS7B_HUMAN Dehydrogenase/reductase SDR famil... | 234 | 0.00000008 | 56.6 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | O31680 | 248 | YKVO_BACSU Uncharacterized oxidoreductase ykv... | 202 | 0.00000009 | 55.8 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 39 | Q99J47 | 323 | DRS7B_MOUSE Dehydrogenase/reductase SDR famil... | 218 | 0.0000001 | 56.6 | 22 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 40 | P50162 | 273 | TRN1_DATST Tropinone reductase 1 OS=Datura st... | 220 | 0.0000002 | 55.5 | 24 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050356; F:tropine dehydrogenase activity; IEA:EC. | | | | | | | | | | | 41 | Q29608 | 291 | DHI1_SAISC Corticosteroid 11-beta-dehydrogena... | 194 | 0.0000003 | 55.1 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 42 | Q6PKH6 | 230 | DR4L2_HUMAN Dehydrogenase/reductase SDR famil... | 181 | 0.0000004 | 53.9 | 27 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 43 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 218 | 0.0000005 | 54.3 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 44 | P37694 | 287 | HETN_NOSS1 Ketoacyl reductase hetN OS=Nostoc ... | 240 | 0.0000006 | 53.9 | 25 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043158; P:heterocyst differentiation; IEA:UniProtKB-KW. | 45 | Q3KPT7 | 245 | BDH2_XENLA 3-hydroxybutyrate dehydrogenase ty... | 239 | 0.0000007 | 53.1 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 46 | Q8WNV7 | 279 | DHRS4_PIG Dehydrogenase/reductase SDR family ... | 200 | 0.0000007 | 53.5 | 26 | 46 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 47 | P94129 | 295 | ACR1_ACIBI Fatty acyl-CoA reductase OS=Acinet... | 196 | 0.0000007 | 53.9 | 26 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW. | 48 | Q7Q732 | 317 | DHRS7_ANOGA Dehydrogenase/reductase SDR famil... | 217 | 0.0000008 | 53.5 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 49 | Q6F7B8 | 303 | ACR1_ACIAD Fatty acyl-CoA reductase OS=Acinet... | 196 | 0.0000009 | 53.5 | 26 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW. | 50 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 191 | 0.000001 | 53.1 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 51 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 191 | 0.000001 | 53.1 | 29 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 52 | Q6QLL4 | 300 | DHI1_CAVPO Corticosteroid 11-beta-dehydrogena... | 248 | 0.000001 | 53.1 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 53 | Q0VFE7 | 309 | DRS7B_XENTR Dehydrogenase/reductase SDR famil... | 293 | 0.000002 | 52.8 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 54 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 249 | 0.000002 | 52.4 | 26 | 45 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 55 | Q9KQH7 | 244 | FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] r... | 243 | 0.000003 | 51.6 | 23 | 42 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 56 | Q49117 | 248 | Y182_METEA Uncharacterized oxidoreductase Mex... | 202 | 0.000004 | 51.2 | 27 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | P71564 | 253 | Y945_MYCTU Uncharacterized oxidoreductase Rv0... | 207 | 0.000004 | 51.2 | 27 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 58 | Q9BY49 | 303 | PECR_HUMAN Peroxisomal trans-2-enoyl-CoA redu... | 234 | 0.000005 | 51.2 | 23 | 41 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0033306; P:phytol metabolic process; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 59 | P50941 | 241 | FABG_RICPR 3-oxoacyl-[acyl-carrier-protein] r... | 220 | 0.000005 | 50.8 | 25 | 42 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 60 | Q91XV4 | 244 | DCXR_MESAU L-xylulose reductase OS=Mesocricet... | 198 | 0.000005 | 50.4 | 28 | 45 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 61 | Q96NR8 | 316 | RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo ... | 62 | 0.000006 | 51.2 | 44 | 65 | GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045494; P:photoreceptor cell maintenance; TAS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. |