| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q8XBJ4 | 263 | UCPA_ECO57 Oxidoreductase ucpA OS=Escherichia... | 234 | 0.0002 | 45.8 | 22 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 152 | P51661 | 386 | DHI2_MOUSE Corticosteroid 11-beta-dehydrogena... | 240 | 0.0002 | 46.2 | 24 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 153 | Q4R5G7 | 312 | DHB12_MACFA Estradiol 17-beta-dehydrogenase 1... | 65 | 0.0003 | 45.8 | 34 | 63 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 154 | A6NNS2 | 312 | DRS7C_HUMAN Dehydrogenase/reductase SDR famil... | 221 | 0.0003 | 45.8 | 24 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 155 | P48587 | 254 | ADH2_DROMN Alcohol dehydrogenase 2 OS=Drosoph... | 252 | 0.0003 | 45.4 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 156 | P37440 | 263 | UCPA_ECOLI Oxidoreductase ucpA OS=Escherichia... | 234 | 0.0003 | 45.4 | 22 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 157 | Q7Z4W1 | 244 | DCXR_HUMAN L-xylulose reductase OS=Homo sapie... | 205 | 0.0003 | 45.4 | 26 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 158 | A6ZLA1 | 347 | MKAR_YEAS7 3-ketoacyl-CoA reductase OS=Saccha... | 46 | 0.0003 | 45.8 | 39 | 76 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 159 | B3LN00 | 347 | MKAR_YEAS1 3-ketoacyl-CoA reductase OS=Saccha... | 46 | 0.0003 | 45.8 | 39 | 76 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 160 | P00335 | 249 | RIDH_ENTAE Ribitol 2-dehydrogenase OS=Enterob... | 211 | 0.0003 | 45.4 | 23 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050255; F:ribitol 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 161 | Q10216 | 286 | YAY8_SCHPO Uncharacterized oxidoreductase C4H... | 202 | 0.0003 | 45.8 | 23 | 37 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005782; C:peroxisomal matrix; ISS:PomBase. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; ISS:PomBase.::GO:0004300; F:enoyl-CoA hydratase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006635; P:fatty acid beta-oxidation; ISS:PomBase. | 162 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 45 | 0.0003 | 46.2 | 49 | 67 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 163 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 45 | 0.0003 | 45.8 | 49 | 67 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 164 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 45 | 0.0003 | 45.8 | 49 | 67 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 165 | Q6CHP1 | 389 | MKAR_YARLI 3-ketoacyl-CoA reductase OS=lipoly... | 130 | 0.0003 | 45.8 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 166 | Q8NBN7 | 331 | RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo ... | 76 | 0.0003 | 45.4 | 34 | 57 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 167 | Q7T2D1 | 336 | RD10B_DANRE Retinol dehydrogenase 10-B OS=Dan... | 233 | 0.0004 | 45.4 | 24 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 168 | Q27404 | 254 | ADH_DROLA Alcohol dehydrogenase OS=Drosophila... | 252 | 0.0004 | 45.1 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 169 | Q9BPW9 | 319 | DHRS9_HUMAN Dehydrogenase/reductase SDR famil... | 229 | 0.0004 | 45.4 | 24 | 40 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016854; F:racemase and epimerase activity; NAS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0030855; P:epithelial cell differentiation; NAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; NAS:UniProtKB. | 170 | Q6PUF4 | 287 | DHI1L_CHICK Hydroxysteroid 11-beta-dehydrogen... | 214 | 0.0004 | 45.1 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 171 | P48585 | 254 | ADH_DROFL Alcohol dehydrogenase OS=Drosophila... | 252 | 0.0004 | 45.1 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 172 | Q02338 | 343 | BDH_HUMAN D-beta-hydroxybutyrate dehydrogenas... | 206 | 0.0004 | 45.4 | 25 | 39 | GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.::GO:0046952; P:ketone body catabolic process; TAS:Reactome. | 173 | P48584 | 254 | ADH_DROBO Alcohol dehydrogenase OS=Drosophila... | 252 | 0.0005 | 44.7 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 174 | Q75A60 | 351 | MKAR_ASHGO 3-ketoacyl-CoA reductase OS=Y-1056... | 58 | 0.0005 | 45.1 | 40 | 64 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 175 | P50197 | 250 | LINC_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,... | 221 | 0.0006 | 44.3 | 23 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW. | 176 | Q9Y394 | 339 | DHRS7_HUMAN Dehydrogenase/reductase SDR famil... | 220 | 0.0006 | 44.7 | 22 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 177 | Q53GQ0 | 312 | DHB12_HUMAN Estradiol 17-beta-dehydrogenase 1... | 59 | 0.0006 | 44.7 | 34 | 66 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome. | 178 | Q5XG41 | 318 | DH12A_XENLA Estradiol 17-beta-dehydrogenase 1... | 74 | 0.0007 | 44.7 | 28 | 59 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 179 | Q13268 | 258 | DHRS2_HUMAN Dehydrogenase/reductase SDR famil... | 214 | 0.0007 | 44.3 | 23 | 45 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB. | 180 | Q8JIS3 | 246 | DER_CHICK D-erythrulose reductase OS=Gallus g... | 208 | 0.0007 | 44.3 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047880; F:erythrulose reductase activity; IEA:EC.::GO:0050038; F:L-xylulose reductase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 181 | O06544 | 250 | Y1144_MYCTU Uncharacterized oxidoreductase Rv... | 204 | 0.0007 | 44.3 | 25 | 46 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
