rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q7RZR2 | 325 | TSC10_NEUCR 3-ketodihydrosphingosine reductas... | 329 | 6e-111 | 333 | 54 | 69 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 2 | Q5BE65 | 369 | TSC10_EMENI 3-ketodihydrosphingosine reductas... | 362 | 6e-71 | 231 | 39 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 3 | P0CR36 | 335 | TSC10_CRYNJ 3-ketodihydrosphingosine reductas... | 325 | 1e-37 | 142 | 32 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 4 | P0CR37 | 335 | TSC10_CRYNB 3-ketodihydrosphingosine reductas... | 325 | 6e-37 | 140 | 31 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 5 | Q9Y7P2 | 503 | YCKF_SCHPO Uncharacterized protein C1450.15 O... | 299 | 5e-32 | 129 | 29 | 53 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; ISS:PomBase.::GO:0000234; F:phosphoethanolamine N-methyltransferase activity; ISS:PomBase. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; ISS:PomBase.::GO:0006506; P:GPI anchor biosynthetic process; ISS:PomBase. | 6 | Q6CE86 | 372 | TSC10_YARLI 3-ketodihydrosphingosine reductas... | 310 | 9e-25 | 106 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 7 | Q6BQK1 | 328 | TSC10_DEBHA 3-ketodihydrosphingosine reductas... | 301 | 1e-23 | 102 | 27 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 8 | Q59RQ2 | 271 | TSC10_CANAL 3-ketodihydrosphingosine reductas... | 277 | 6e-23 | 100 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 9 | P38342 | 320 | TSC10_YEAST 3-ketodihydrosphingosine reductas... | 297 | 4e-20 | 92.4 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; IDA:SGD. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:SGD.::GO:0030148; P:sphingolipid biosynthetic process; IDA:SGD. | 10 | Q2KIJ5 | 331 | KDSR_BOVIN 3-ketodihydrosphingosine reductase... | 300 | 6e-18 | 86.3 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 11 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 299 | 1e-17 | 85.5 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 12 | Q758B6 | 307 | TSC10_ASHGO 3-ketodihydrosphingosine reductas... | 310 | 3e-17 | 84.3 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 13 | Q556J2 | 334 | KDSR_DICDI 3-ketodihydrosphingosine reductase... | 279 | 3e-16 | 81.6 | 23 | 46 | GO:0042406; C:extrinsic to endoplasmic reticulum membrane; ISS:dictyBase. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase. | 14 | Q6CLN0 | 313 | TSC10_KLULA 3-ketodihydrosphingosine reductas... | 308 | 0.000000000000001 | 79.7 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 15 | Q6GV12 | 332 | KDSR_MOUSE 3-ketodihydrosphingosine reductase... | 313 | 0.000000000000007 | 77.8 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; IGI:MGI. | 16 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 208 | 0.00000000000006 | 75.1 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | Q566S6 | 309 | DRS7B_DANRE Dehydrogenase/reductase SDR famil... | 242 | 0.000000000002 | 70.5 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q6FQ42 | 363 | TSC10_CANGA 3-ketodihydrosphingosine reductas... | 141 | 0.000000000007 | 69.3 | 33 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 19 | Q5RCF8 | 278 | DHRS4_PONAB Dehydrogenase/reductase SDR famil... | 234 | 0.00000000003 | 66.6 | 26 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 20 | Q9BTZ2 | 278 | DHRS4_HUMAN Dehydrogenase/reductase SDR famil... | 234 | 0.00000000003 | 66.6 | 26 | 48 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.::GO:0018455; F:alcohol dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.::GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; IDA:UniProtKB.] | 21 | Q5RJY4 | 325 | DRS7B_RAT Dehydrogenase/reductase SDR family ... | 229 | 0.00000000005 | 66.6 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | Q8VID1 | 279 | DHRS4_RAT Dehydrogenase/reductase SDR family ... | 208 | 0.00000000009 | 65.5 | 28 | 47 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IDA:RGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 23 | Q8T197 | 316 | DHRS7_DICDI Dehydrogenase/reductase SDR famil... | 236 | 0.0000000001 | 65.1 | 25 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | P0CG22 | 281 | DR4L1_HUMAN Putative dehydrogenase/reductase ... | 241 | 0.0000000001 | 64.7 | 27 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 25 | Q4A054 | 234 | Y0419_STAS1 Uncharacterized oxidoreductase SS... | 249 | 0.0000000006 | 62 | 25 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q8SPU8 | 279 | DHRS4_BOVIN Dehydrogenase/reductase SDR famil... | 212 | 0.000000002 | 61.2 | 26 | 47 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 27 | Q99LB2 | 279 | DHRS4_MOUSE Dehydrogenase/reductase SDR famil... | 208 | 0.000000003 | 60.8 | 27 | 46 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 28 | Q3T0R4 | 325 | DRS7B_BOVIN Dehydrogenase/reductase SDR famil... | 204 | 0.000000007 | 60.1 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 29 | P25145 | 248 | Y432_LISMO Uncharacterized oxidoreductase Lmo... | 185 | 0.000000008 | 59.3 | 28 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | Q0IH28 | 323 | DRS7B_XENLA Dehydrogenase/reductase SDR famil... | 294 | 0.00000001 | 59.7 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 31 | Q92EK7 | 248 | Y452_LISIN Uncharacterized oxidoreductase Lin... | 185 | 0.00000001 | 58.9 | 28 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |