| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
631 | Q91Z69 | 1062 | SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating p... | 52 | 0.66 | 38.1 | 31 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI. | | | | | | | | | | GO:0016477; P:cell migration; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 632 | Q55CE0 | 677 | MKCF_DICDI Probable serine/threonine-protein ... | 54 | 0.68 | 37.7 | 33 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 633 | Q91WL0 | 600 | ES8L3_MOUSE Epidermal growth factor receptor ... | 61 | 0.69 | 37.7 | 28 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 634 | Q91Z67 | 1071 | FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p... | 52 | 0.69 | 38.1 | 31 | 46 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 635 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 47 | 0.69 | 37.7 | 38 | 57 | | | | | | | | | | | | | | | | | | | | | | 636 | O08839 | 588 | BIN1_RAT Myc box-dependent-interacting protei... | 75 | 0.7 | 37.7 | 32 | 45 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0044300; C:cerebellar mossy fiber; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043196; C:varicosity; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; IMP:RGD.::GO:0043547; P:positive regulation of GTPase activity; IDA:RGD. | 637 | P00520 | 1123 | ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mu... | 55 | 0.71 | 37.7 | 31 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:MGI. | 638 | P00519 | 1130 | ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Ho... | 55 | 0.76 | 37.7 | 31 | 53 | GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:BHF-UCL.::GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; TAS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006975; P:DNA damage induced protein phosphorylation; IDA:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; TAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006298; P:mismatch repair; TAS:ProtInc.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:2001020; P:regulation of response to DNA damage stimulus; IDA:UniProtKB.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; TAS:ProtInc. | 639 | Q07840 | 426 | EM13_ECHMU Antigen EM13 OS=Echinococcus multi... | 47 | 0.78 | 37.4 | 38 | 57 | | | | | | | | | | | | | | | | | | | | | | 640 | Q9JIR0 | 1847 | RIMB1_RAT Peripheral-type benzodiazepine rece... | 70 | 0.85 | 37.7 | 34 | 47 | GO:0005739; C:mitochondrion; IDA:RGD. | | | | | | | | | | | | | | | | | | | | | 641 | Q6CHN0 | 1136 | SLA1_YARLI Actin cytoskeleton-regulatory comp... | 65 | 0.86 | 37.7 | 35 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 642 | Q15700 | 870 | DLG2_HUMAN Disks large homolog 2 OS=Homo sapi... | 57 | 0.89 | 37.4 | 32 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 643 | Q62936 | 849 | DLG3_RAT Disks large homolog 3 OS=Rattus norv... | 45 | 0.9 | 37.4 | 42 | 56 | GO:0043198; C:dendritic shaft; IDA:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 644 | P70175 | 849 | DLG3_MOUSE Disks large homolog 3 OS=Mus muscu... | 45 | 0.91 | 37.4 | 42 | 56 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 645 | Q32LM0 | 365 | SHLB1_BOVIN Endophilin-B1 OS=Bos taurus (Bovi... | 61 | 0.96 | 37 | 31 | 51 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 646 | O75400 | 957 | PR40A_HUMAN Pre-mRNA-processing factor 40 hom... | 45 | 0.97 | 37.4 | 42 | 60 | GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 647 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 66 | 0.97 | 37.4 | 30 | 48 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 648 | Q92796 | 817 | DLG3_HUMAN Disks large homolog 3 OS=Homo sapi... | 45 | 0.99 | 37.4 | 42 | 56 | GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0019902; F:phosphatase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 649 | P78352 | 724 | DLG4_HUMAN Disks large homolog 4 OS=Homo sapi... | 60 | 1 | 37.4 | 33 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030863; C:cortical cytoskeleton; IDA:UniProtKB.::GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0045184; P:establishment of protein localization; IDA:BHF-UCL.::GO:0007612; P:learning; TAS:ProtInc.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0050806; P:positive regulation of synaptic transmission; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; IDA:BHF-UCL.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0007165; P:signal transduction; TAS:ProtInc. | 650 | Q0VC16 | 1905 | MIA3_BOVIN Melanoma inhibitory activity prote... | 57 | 1 | 37.4 | 28 | 51 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006887; P:exocytosis; ISS:UniProtKB.::GO:0015031; P:protein transport; ISS:UniProtKB. | 651 | O95153 | 1857 | RIMB1_HUMAN Peripheral-type benzodiazepine re... | 70 | 1 | 37.4 | 34 | 47 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0030156; F:benzodiazepine receptor binding; IPI:UniProtKB. | | | | | | | | | | | 652 | Q63622 | 852 | DLG2_RAT Disks large homolog 2 OS=Rattus norv... | 57 | 1.1 | 37.4 | 32 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0045161; P:neuronal ion channel clustering; IMP:RGD.::GO:0043113; P:receptor clustering; IMP:RGD. | 653 | B3DLB3 | 433 | ANM2_XENTR Protein arginine N-methyltransfera... | 44 | 1.1 | 37 | 36 | 57 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB. | 654 | Q5RC07 | 716 | ES8L2_PONAB Epidermal growth factor receptor ... | 66 | 1.1 | 37.4 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 655 | P42690 | 506 | SRK4_SPOLA Tyrosine-protein kinase isoform SR... | 48 | 1.1 | 37 | 38 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 656 | Q91XM9 | 852 | DLG2_MOUSE Disks large homolog 2 OS=Mus muscu... | 57 | 1.1 | 37.4 | 32 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI. | 657 | Q86WN1 | 690 | FCSD1_HUMAN FCH and double SH3 domains protei... | 66 | 1.1 | 37 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 658 | A1C4A5 | 1253 | MYO1_ASPCL Myosin-1 OS=3887 / NRRL 1). GN=myo... | 50 | 1.2 | 37.4 | 28 | 54 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 659 | P42686 | 505 | SRK1_SPOLA Tyrosine-protein kinase isoform SR... | 48 | 1.2 | 37 | 38 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 660 | Q99K30 | 729 | ES8L2_MOUSE Epidermal growth factor receptor ... | 69 | 1.2 | 37 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 661 | D6PVB5 | 320 | SHO1B_HORWE High osmolarity signaling protein... | 55 | 1.2 | 36.6 | 36 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. |
