rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q6DD51 | 1205 | CSKI2_XENLA Caskin-2 OS=Xenopus laevis (Afric... | 65 | 0.095 | 40.8 | 35 | 55 | | | | | | | | | | | | | | | | | | | | | | 572 | Q6DII7 | 345 | SKAP1_XENTR Src kinase-associated phosphoprot... | 59 | 0.1 | 40 | 31 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 573 | Q6CP77 | 357 | SHO1_KLULA High osmolarity signaling protein ... | 55 | 0.11 | 40 | 40 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 574 | A7E3N7 | 446 | NOXA1_RAT NADPH oxidase activator 1 OS=Rattus... | 64 | 0.11 | 40 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016176; F:superoxide-generating NADPH oxidase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 575 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 54 | 0.11 | 40 | 37 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 576 | O35177 | 833 | CASL_MOUSE Enhancer of filamentation 1 OS=Mus... | 62 | 0.11 | 40.4 | 35 | 55 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0000922; C:spindle pole; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 577 | A7E3N2 | 527 | NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu... | 57 | 0.12 | 40 | 33 | 49 | GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD. | 578 | O75995 | 380 | SASH3_HUMAN SAM and SH3 domain-containing pro... | 72 | 0.13 | 39.7 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 579 | Q99469 | 402 | STAC_HUMAN SH3 and cysteine-rich domain-conta... | 52 | 0.13 | 39.7 | 35 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 580 | Q8VHK1 | 1201 | CSKI2_MOUSE Caskin-2 OS=Mus musculus (Mouse).... | 65 | 0.14 | 40 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 581 | Q7TNR9 | 484 | ARHG4_MOUSE Rho guanine nucleotide exchange f... | 70 | 0.14 | 40 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 582 | P00522 | 1620 | ABL_DROME Tyrosine-protein kinase Abl OS=Dros... | 56 | 0.15 | 40 | 32 | 55 | GO:0045179; C:apical cortex; IDA:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005911; C:cell-cell junction; IDA:FlyBase.::GO:0005829; C:cytosol; IDA:FlyBase.::GO:0019897; C:extrinsic to plasma membrane; IDA:FlyBase.::GO:0005927; C:muscle tendon junction; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007417; P:central nervous system development; IGI:FlyBase.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0003382; P:epithelial cell morphogenesis; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; TAS:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0007370; P:ventral furrow formation; IMP:FlyBase. | 583 | P42687 | 497 | SPK1_DUGTI Tyrosine-protein kinase SPK-1 OS=D... | 78 | 0.15 | 39.7 | 32 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 584 | Q8WXE0 | 1202 | CSKI2_HUMAN Caskin-2 OS=Homo sapiens (Human).... | 65 | 0.16 | 40 | 34 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 585 | Q8K352 | 380 | SASH3_MOUSE SAM and SH3 domain-containing pro... | 72 | 0.16 | 39.7 | 28 | 47 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IMP:MGI.::GO:0002639; P:positive regulation of immunoglobulin production; IMP:MGI.::GO:0032729; P:positive regulation of interferon-gamma production; IMP:MGI.::GO:0032733; P:positive regulation of interleukin-10 production; IMP:MGI.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:MGI.::GO:0046622; P:positive regulation of organ growth; IMP:MGI.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:MGI. | 586 | Q6PG29 | 341 | SKAP2_DANRE Src kinase-associated phosphoprot... | 54 | 0.16 | 39.3 | 37 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 587 | Q6PFY1 | 688 | FCSD1_MOUSE FCH and double SH3 domains protei... | 85 | 0.16 | 39.7 | 31 | 47 | | | | | | | | | | | | | | | | | | | | | | 588 | Q5PYH7 | 881 | DLG2_DANRE Disks large homolog 2 OS=Danio rer... | 57 | 0.17 | 40 | 39 | 54 | | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0050808; P:synapse organization; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:UniProtKB. | 589 | Q9BVN2 | 902 | RUSC1_HUMAN RUN and SH3 domain-containing pro... | 53 | 0.18 | 39.7 | 36 | 55 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | | 590 | A8N2Y6 | 1277 | MYO1_COPC7 Myosin-1 OS=9003) (Inky cap fungus... | 59 | 0.19 | 39.7 | 34 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 591 | Q5FVW6 | 328 | SKAP2_XENTR Src kinase-associated phosphoprot... | 54 | 0.2 | 39.3 | 35 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 592 | Q7SDM3 | 1235 | MYO1_NEUCR Myosin-1 OS=1257 / FGSC 987). GN=m... | 53 | 0.21 | 39.7 | 26 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 593 | Q8N3R9 | 675 | MPP5_HUMAN MAGUK p55 subfamily member 5 OS=Ho... | 91 | 0.22 | 39.3 | 27 | 44 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:BHF-UCL. | | | | | | | | | | GO:0070830; P:tight junction assembly; TAS:Reactome. | 594 | D8PSG0 | 331 | SHO1_SCHCM High osmolarity signaling protein ... | 69 | 0.23 | 38.9 | 35 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 595 | Q5RDQ2 | 675 | MPP5_PONAB MAGUK p55 subfamily member 5 OS=Po... | 91 | 0.23 | 39.3 | 27 | 44 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 596 | A0JNJ1 | 403 | STAC_BOVIN SH3 and cysteine-rich domain-conta... | 54 | 0.24 | 38.9 | 33 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 597 | Q8BG26 | 893 | RUSC1_MOUSE RUN and SH3 domain-containing pro... | 53 | 0.27 | 39.3 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 598 | P02549 | 2419 | SPTA1_HUMAN Spectrin alpha chain, erythrocyte... | 64 | 0.27 | 39.3 | 30 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; TAS:BHF-UCL.::GO:0008091; C:spectrin; TAS:ProtInc.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007015; P:actin filament organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. | 599 | O00499 | 593 | BIN1_HUMAN Myc box-dependent-interacting prot... | 96 | 0.27 | 38.9 | 30 | 45 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 600 | Q9JLB2 | 675 | MPP5_MOUSE MAGUK p55 subfamily member 5 OS=Mu... | 91 | 0.29 | 38.9 | 27 | 44 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0043219; C:lateral loop; IDA:BHF-UCL.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032287; P:peripheral nervous system myelin maintenance; IMP:BHF-UCL.::GO:0035750; P:protein localization to myelin sheath abaxonal region; IMP:BHF-UCL. | 601 | Q9UUD0 | 501 | YNQA_SCHPO Uncharacterized protein C19C2.10 O... | 57 | 0.31 | 38.9 | 39 | 54 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | |