rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
811 | P28482 | 360 | MK01_HUMAN Mitogen-activated protein kinase 1... | 207 | 0.000000000003 | 72.8 | 30 | 46 | GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 812 | P63086 | 358 | MK01_RAT Mitogen-activated protein kinase 1 O... | 207 | 0.000000000003 | 72.8 | 30 | 46 | GO:0033267; C:axon part; IDA:RGD.::GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.::GO:0008134; F:transcription factor binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000189; P:MAPK import into nucleus; IDA:RGD.::GO:0030335; P:positive regulation of cell migration; IEP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IEP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IEP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IDA:RGD.::GO:0019233; P:sensory perception of pain; IMP:UniProtKB. | 813 | P63085 | 358 | MK01_MOUSE Mitogen-activated protein kinase 1... | 207 | 0.000000000003 | 72.8 | 30 | 46 | GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0031143; C:pseudopodium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:MGI.::GO:0001784; F:phosphotyrosine binding; IMP:MGI.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0019858; P:cytosine metabolic process; IDA:MGI.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IDA:MGI.::GO:0045596; P:negative regulation of cell differentiation; IGI:MGI.::GO:0009887; P:organ morphogenesis; IDA:MGI.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB. | 814 | P09215 | 673 | KPCD_RAT Protein kinase C delta type OS=Rattu... | 193 | 0.000000000003 | 73.9 | 27 | 47 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0070976; F:TIR domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0015810; P:aspartate transport; IMP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0032963; P:collagen metabolic process; IMP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 815 | P39009 | 513 | DUN1_YEAST DNA damage response protein kinase... | 223 | 0.000000000003 | 73.6 | 29 | 46 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0048478; P:replication fork protection; IGI:SGD. | 816 | P32485 | 435 | HOG1_YEAST Mitogen-activated protein kinase H... | 350 | 0.000000000003 | 73.2 | 27 | 42 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0006972; P:hyperosmotic response; IMP:SGD.::GO:0046020; P:negative regulation of transcription from RNA polymerase II promoter by pheromones; IEP:SGD.::GO:0007231; P:osmosensory signaling pathway; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0046685; P:response to arsenic-containing substance; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 817 | O95835 | 1130 | LATS1_HUMAN Serine/threonine-protein kinase L... | 245 | 0.000000000003 | 74.3 | 23 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051220; P:cytoplasmic sequestering of protein; IMP:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; IDA:BHF-UCL.::GO:0009755; P:hormone-mediated signaling pathway; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0000819; P:sister chromatid segregation; IDA:UniProtKB. | 818 | O88643 | 545 | PAK1_MOUSE Serine/threonine-protein kinase PA... | 229 | 0.000000000003 | 73.6 | 28 | 45 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042060; P:wound healing; ISS:UniProtKB. | 819 | P0CP66 | 366 | CPK1_CRYNJ Mitogen-activated protein kinase C... | 202 | 0.000000000003 | 72.4 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 820 | P0CP67 | 366 | CPK1_CRYNB Mitogen-activated protein kinase C... | 202 | 0.000000000003 | 72.4 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 821 | Q0CL79 | 1342 | SEPH_ASPTN Cytokinesis protein sepH OS=Asperg... | 220 | 0.000000000003 | 74.3 | 30 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 822 | B4GXC2 | 755 | DCLK_DROPE Serine/threonine-protein kinase GL... | 255 | 0.000000000003 | 73.9 | 28 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 823 | Q21734 | 784 | KS6A1_CAEEL Putative ribosomal protein S6 kin... | 146 | 0.0000008 | 56.2 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 824 | P45984 | 424 | MK09_HUMAN Mitogen-activated protein kinase 9... | 206 | 0.000000000003 | 72.8 | 33 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008134; F:transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 825 | Q80YP0 | 303 | CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus m... | 221 | 0.000000000003 | 71.6 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 826 | Q86CS2 | 668 | ATG1_DICDI Serine/threonine-protein kinase at... | 199 | 0.000000000003 | 73.6 | 32 | 47 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0048102; P:autophagic cell death; IMP:dictyBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:dictyBase.::GO:0016236; P:macroautophagy; IMP:dictyBase.::GO:0070265; P:necrotic cell death; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 827 | Q94CG0 | 416 | CIPKL_ARATH CBL-interacting serine/threonine-... | 196 | 0.000000000003 | 72.8 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 828 | P36582 | 988 | PCK1_SCHPO Protein kinase C-like 1 OS=Schizos... | 204 | 0.000000000003 | 73.9 | 25 | 46 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 829 | Q53N72 | 498 | MPK15_ORYSJ Mitogen-activated protein kinase ... | 359 | 0.000000000003 | 73.2 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 830 | Q2QMI0 | 454 | CIPK4_ORYSJ CBL-interacting protein kinase 4 ... | 225 | 0.000000000003 | 72.8 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 831 | Q54EY4 | 562 | DST3_DICDI Serine/threonine-protein kinase ds... | 211 | 0.000000000003 | 73.2 | 31 | 49 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. | 832 | Q4I5U9 | 473 | BUR1_GIBZE Serine/threonine-protein kinase BU... | 220 | 0.000000000003 | 73.2 | 27 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 833 | Q5R7A7 | 496 | SGK3_PONAB Serine/threonine-protein kinase Sg... | 252 | 0.000000000003 | 73.2 | 28 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 834 | Q96BR1 | 496 | SGK3_HUMAN Serine/threonine-protein kinase Sg... | 252 | 0.000000000003 | 73.2 | 28 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.::GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0006950; P:response to stress; TAS:ProtInc. | 835 | P49186 | 423 | MK09_RAT Mitogen-activated protein kinase 9 O... | 202 | 0.000000000003 | 72.8 | 32 | 46 | GO:0044445; C:cytosolic part; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IMP:RGD.::GO:0004705; F:JUN kinase activity; IDA:RGD.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071347; P:cellular response to interleukin-1; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0034644; P:cellular response to UV; IMP:RGD.::GO:0007417; P:central nervous system development; IEP:RGD.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0010770; P:positive regulation of cell morphogenesis involved in differentiation; IMP:RGD.::GO:0032722; P:positive regulation of chemokine production; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IMP:RGD.::GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IMP:RGD.::GO:0032308; P:positive regulation of prostaglandin secretion; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD.::GO:0006626; P:protein targeting to mitochondrion; IEP:RGD.::GO:0046328; P:regulation of JNK cascade; IMP:RGD.::GO:0031396; P:regulation of protein ubiquitination; IMP:RGD.::GO:0001836; P:release of cytochrome c from mitochondria; IMP:RGD.::GO:0014075; P:response to amine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 836 | O42565 | 615 | LIMK1_XENLA LIM domain kinase 1 OS=Xenopus la... | 244 | 0.000000000003 | 73.6 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 837 | P45983 | 427 | MK08_HUMAN Mitogen-activated protein kinase 8... | 194 | 0.000000000004 | 72.8 | 31 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0035033; F:histone deacetylase regulator activity; IMP:BHF-UCL.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0090045; P:positive regulation of deacetylase activity; IMP:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0009411; P:response to UV; IDA:MGI.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 838 | A8XWC4 | 760 | DKF1_CAEBR Serine/threonine-protein kinase dk... | 196 | 0.000000000004 | 73.6 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 839 | Q5B4Z3 | 1346 | SEPH_EMENI Cytokinesis protein sepH OS=194 / ... | 192 | 0.000000000004 | 73.9 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 840 | Q54TH6 | 597 | Y9863_DICDI Probable serine/threonine-protein... | 206 | 0.000000000004 | 73.2 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 841 | Q9HGY5 | 326 | PHO85_CANAX Negative regulator of the PHO sys... | 207 | 0.000000000004 | 71.6 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | |