| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q99683 | 1374 | M3K5_HUMAN Mitogen-activated protein kinase k... | 195 | 0.00000000000001 | 81.6 | 33 | 48 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.::GO:0010421; P:hydrogen peroxide-mediated programmed cell death; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 422 | Q8IBS5 | 528 | CDPK4_PLAF7 Calcium-dependent protein kinase ... | 200 | 0.00000000000001 | 80.9 | 32 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 423 | Q00535 | 292 | CDK5_HUMAN Cyclin-dependent kinase 5 OS=Homo ... | 199 | 0.00000000000002 | 78.6 | 29 | 46 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; IDA:UniProtKB.::GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:DFLAT.::GO:0051402; P:neuron apoptotic process; TAS:UniProtKB.::GO:0001764; P:neuron migration; TAS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IDA:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0007416; P:synapse assembly; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; TAS:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB. | 424 | O35099 | 1380 | M3K5_MOUSE Mitogen-activated protein kinase k... | 195 | 0.00000000000002 | 81.6 | 33 | 48 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 425 | Q91820 | 407 | AURAA_XENLA Aurora kinase A-A OS=Xenopus laev... | 247 | 0.00000000000002 | 80.1 | 27 | 43 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB. | 426 | P49615 | 292 | CDK5_MOUSE Cyclin-dependent kinase 5 OS=Mus m... | 199 | 0.00000000000002 | 78.6 | 29 | 46 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030549; F:acetylcholine receptor activator activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; IDA:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:MGI.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0048148; P:behavioral response to cocaine; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0021697; P:cerebellar cortex formation; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0006886; P:intracellular protein transport; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IMP:MGI.::GO:0008045; P:motor axon guidance; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; IMP:MGI.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0031914; P:negative regulation of synaptic plasticity; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:MGI.::GO:0032801; P:receptor catabolic process; IMP:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.::GO:0014044; P:Schwann cell development; IMP:MGI.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 427 | Q02399 | 292 | CDK5_BOVIN Cyclin-dependent kinase 5 OS=Bos t... | 199 | 0.00000000000002 | 78.6 | 29 | 46 | GO:0030424; C:axon; ISS:AgBase.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030426; C:growth cone; ISS:AgBase.::GO:0030027; C:lamellipodium; ISS:AgBase.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030549; F:acetylcholine receptor activator activity; ISS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:AgBase.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:AgBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; ISS:AgBase.::GO:0009790; P:embryo development; ISS:AgBase.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:AgBase.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB. | 428 | P51952 | 329 | CDK7_RAT Cyclin-dependent kinase 7 OS=Rattus ... | 197 | 0.00000000000002 | 79 | 29 | 44 | GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; TAS:RGD.::GO:0005856; C:cytoskeleton; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD.::GO:0008094; F:DNA-dependent ATPase activity; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB. | 429 | Q54PX0 | 496 | Y4251_DICDI Probable serine/threonine-protein... | 191 | 0.00000000000002 | 80.5 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 430 | Q03114 | 292 | CDK5_RAT Cyclin-dependent kinase 5 OS=Rattus ... | 199 | 0.00000000000002 | 78.6 | 29 | 46 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; TAS:RGD.::GO:0016533; C:cyclin-dependent protein kinase 5 holoenzyme complex; IDA:RGD.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:RGD.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0051402; P:neuron apoptotic process; IMP:RGD.::GO:0006913; P:nucleocytoplasmic transport; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0045055; P:regulated secretory pathway; IMP:RGD.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0009611; P:response to wounding; IMP:RGD.::GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; IMP:RGD. | 431 | Q9Z335 | 417 | SBK1_RAT Serine/threonine-protein kinase SBK1... | 321 | 0.00000000000002 | 80.1 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD. | 432 | Q9JLS3 | 1235 | TAOK2_RAT Serine/threonine-protein kinase TAO... | 198 | 0.00000000000002 | 81.3 | 30 | 49 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB. | 433 | P32491 | 506 | MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Sa... | 294 | 0.00000000000002 | 80.5 | 27 | 44 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030242; P:peroxisome degradation; IGI:SGD.::GO:0007165; P:signal transduction; IMP:SGD. | 434 | Q5AHK2 | 608 | SSN3_CANAL Serine/threonine-protein kinase SS... | 157 | 0.00000000000002 | 80.9 | 33 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 435 | Q9QY01 | 1037 | ULK2_MOUSE Serine/threonine-protein kinase UL... | 197 | 0.00000000000002 | 81.3 | 33 | 46 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0048675; P:axon extension; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010506; P:regulation of autophagy; IMP:UniProtKB.::GO:0042594; P:response to starvation; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 436 | O62618 | 366 | MK14A_DROME Mitogen-activated protein kinase ... | 209 | 0.00000000000002 | 79.3 | 32 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; TAS:FlyBase. | | | | | | | | | | GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0008348; P:negative regulation of antimicrobial humoral response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0080134; P:regulation of response to stress; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0006970; P:response to osmotic stress; IDA:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase. | 437 | A5GFW1 | 402 | AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)... | 33 | 3.6 | 34.7 | 36 | 64 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 438 | P06493 | 297 | CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo ... | 250 | 0.00000000000002 | 78.2 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0007098; P:centrosome cycle; TAS:UniProtKB.::GO:0006281; P:DNA repair; TAS:UniProtKB.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0007344; P:pronuclear fusion; TAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045995; P:regulation of embryonic development; TAS:UniProtKB.::GO:0014038; P:regulation of Schwann cell differentiation; TAS:UniProtKB.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 439 | P53349 | 1493 | M3K1_MOUSE Mitogen-activated protein kinase k... | 227 | 0.00000000000002 | 81.3 | 26 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL. | 440 | Q869N2 | 852 | PAKB_DICDI Serine/threonine-protein kinase pa... | 198 | 0.00000000000002 | 80.9 | 27 | 46 | GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0006907; P:pinocytosis; IMP:dictyBase.::GO:0050766; P:positive regulation of phagocytosis; IMP:dictyBase. | 441 | O55099 | 343 | AURKB_RAT Aurora kinase B OS=Rattus norvegicu... | 268 | 0.00000000000002 | 79 | 25 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:RGD.::GO:0005819; C:spindle; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0008283; P:cell proliferation; IEP:RGD.::GO:0000910; P:cytokinesis; IDA:RGD.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 442 | Q07785 | 288 | CDC2H_PLAFK Cell division control protein 2 h... | 210 | 0.00000000000002 | 78.2 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 443 | P61075 | 288 | CDC2H_PLAF7 Cell division control protein 2 h... | 210 | 0.00000000000002 | 78.2 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 444 | O55173 | 559 | PDPK1_RAT 3-phosphoinositide-dependent protei... | 196 | 0.00000000000002 | 80.5 | 30 | 51 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 445 | P48734 | 297 | CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos t... | 250 | 0.00000000000002 | 78.2 | 28 | 46 | GO:0030496; C:midbody; ISS:AgBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0005876; C:spindle microtubule; ISS:AgBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 446 | P34101 | 595 | FHKC_DICDI Probable serine/threonine-protein ... | 198 | 0.00000000000002 | 80.5 | 30 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; ISS:dictyBase. | 447 | P35567 | 302 | CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xe... | 251 | 0.00000000000002 | 78.2 | 27 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 448 | Q8IYT8 | 1036 | ULK2_HUMAN Serine/threonine-protein kinase UL... | 197 | 0.00000000000002 | 80.9 | 33 | 46 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:0042594; P:response to starvation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 449 | Q55GS4 | 366 | CDK10_DICDI Probable cyclin-dependent kinase ... | 290 | 0.00000000000002 | 79 | 27 | 42 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051726; P:regulation of cell cycle; ISS:dictyBase. | 450 | Q13164 | 816 | MK07_HUMAN Mitogen-activated protein kinase 7... | 211 | 0.00000000000002 | 80.9 | 30 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IGI:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IGI:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 451 | Q7YRC6 | 344 | AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo... | 201 | 0.00000000000002 | 78.6 | 28 | 52 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. |
