rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q498M5 | 735 | SH3R2_RAT Putative E3 ubiquitin-protein ligas... | 48 | 0.41 | 37.4 | 35 | 50 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 362 | Q96PX1 | 679 | RN157_HUMAN RING finger protein 157 OS=Homo s... | 47 | 0.42 | 37.4 | 32 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 363 | Q8BZT2 | 735 | SH3R2_MOUSE Putative E3 ubiquitin-protein lig... | 48 | 0.42 | 37.4 | 35 | 50 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 364 | B6IFN4 | 1503 | LTN1_CAEBR E3 ubiquitin-protein ligase lister... | 55 | 0.42 | 37.4 | 36 | 51 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 365 | Q09268 | 610 | YQDA_CAEEL Uncharacterized RING finger protei... | 47 | 0.43 | 37.4 | 32 | 60 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 366 | Q5TJF3 | 406 | RING1_CANFA E3 ubiquitin-protein ligase RING1... | 52 | 0.47 | 37 | 35 | 54 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 367 | Q54L48 | 87 | APC11_DICDI Anaphase-promoting complex subuni... | 44 | 0.47 | 34.7 | 36 | 52 | GO:0005680; C:anaphase-promoting complex; ISS:dictyBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase. | 368 | Q7Z569 | 592 | BRAP_HUMAN BRCA1-associated protein OS=Homo s... | 44 | 0.58 | 37 | 32 | 57 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:MGI. | 369 | Q5SDR3 | 326 | BMI1_CHICK Polycomb complex protein BMI-1 OS=... | 34 | 0.59 | 36.6 | 35 | 53 | GO:0031519; C:PcG protein complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 370 | Q5R8L2 | 326 | BMI1_PONAB Polycomb complex protein BMI-1 OS=... | 34 | 0.6 | 36.6 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 371 | P35226 | 326 | BMI1_HUMAN Polycomb complex protein BMI-1 OS=... | 34 | 0.6 | 36.6 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0035102; C:PRC1 complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0030097; P:hemopoiesis; IEP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0007379; P:segment specification; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 372 | Q32KX7 | 326 | BMI1_BOVIN Polycomb complex protein BMI-1 OS=... | 34 | 0.6 | 36.6 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 373 | P25916 | 324 | BMI1_MOUSE Polycomb complex protein BMI-1 OS=... | 30 | 0.61 | 36.6 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016604; C:nuclear body; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0016573; P:histone acetylation; IGI:MGI.::GO:0016574; P:histone ubiquitination; IDA:MGI.::GO:0006959; P:humoral immune response; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:HGNC.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IMP:HGNC.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0021903; P:rostrocaudal neural tube patterning; IMP:MGI.::GO:0048103; P:somatic stem cell division; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 374 | A8WGF4 | 1189 | IF122_XENTR Intraflagellar transport protein ... | 38 | 0.62 | 37 | 45 | 55 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 375 | A9JTG5 | 714 | HOIL1_DANRE RanBP-type and C3HC4-type zinc fi... | 45 | 0.62 | 37 | 40 | 58 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0071600; P:otic vesicle morphogenesis; IMP:ZFIN.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 376 | Q640D5 | 323 | BMI1B_XENLA Polycomb complex protein BMI-1-B ... | 51 | 0.65 | 36.2 | 29 | 49 | GO:0031519; C:PcG protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 377 | Q9TST0 | 326 | BMI1_FELCA Polycomb complex protein BMI-1 OS=... | 30 | 0.65 | 36.2 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031519; C:PcG protein complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 378 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 46 | 0.66 | 37 | 33 | 57 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 379 | Q587N7 | 515 | TRIM5_CHLAE Tripartite motif-containing prote... | 60 | 0.66 | 36.6 | 32 | 50 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 380 | Q96BH1 | 459 | RNF25_HUMAN E3 ubiquitin-protein ligase RNF25... | 72 | 0.66 | 36.6 | 24 | 39 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB. | 381 | Q96CA5 | 298 | BIRC7_HUMAN Baculoviral IAP repeat-containing... | 81 | 0.68 | 36.2 | 26 | 46 | GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:UniProtKB.::GO:0019899; F:enzyme binding; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; NAS:UniProtKB.::GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; NAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.::GO:0070247; P:regulation of natural killer cell apoptotic process; IDA:UniProtKB. | 382 | Q9W5E1 | 108 | RBX1A_DROME RING-box protein 1A OS=Drosophila... | 96 | 0.68 | 34.3 | 27 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0019915; P:lipid storage; IDA:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IMP:FlyBase.::GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB. | 383 | Q9FGI1 | 1873 | LTN1_ARATH E3 ubiquitin-protein ligase lister... | 51 | 0.73 | 37 | 31 | 49 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 384 | P38748 | 585 | ETP1_YEAST RING finger protein ETP1 OS=Saccha... | 43 | 0.74 | 36.6 | 30 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045471; P:response to ethanol; IMP:SGD. | 385 | Q10322 | 267 | DMA1_SCHPO Probable E3 ubiquitin-protein liga... | 78 | 0.81 | 35.8 | 31 | 50 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0031030; P:negative regulation of septation initiation signaling cascade; TAS:PomBase. | 386 | Q8VYC8 | 578 | RIN2_ARATH E3 ubiquitin protein ligase RIN2 O... | 61 | 0.81 | 36.6 | 34 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0034052; P:positive regulation of plant-type hypersensitive response; IGI:TAIR. | 387 | O74349 | 1610 | LTN1_SCHPO E3 ubiquitin-protein ligase lister... | 52 | 0.82 | 36.6 | 40 | 50 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; NAS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase. | 388 | Q54CX4 | 903 | Y5521_DICDI Uncharacterized protein DDB_G0292... | 45 | 0.83 | 36.6 | 38 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 389 | Q9CR50 | 261 | ZN363_MOUSE RING finger and CHY zinc finger d... | 42 | 0.94 | 35.8 | 43 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 390 | Q136B3 | 359 | LPXD_RHOPS UDP-3-O-acylglucosamine N-acyltran... | 69 | 0.95 | 35.8 | 33 | 43 | | | | | | | | | | | GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW. | 391 | Q96PM5 | 261 | ZN363_HUMAN RING finger and CHY zinc finger d... | 42 | 0.99 | 35.4 | 43 | 55 | GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB. |