| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9HAU5 | 1272 | RENT2_HUMAN Regulator of nonsense transcripts... | 937 | 3e-151 | 492 | 33 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0035145; C:exon-exon junction complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010467; P:gene expression; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:HGNC.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB. | 2 | O13824 | 1049 | NMD2_SCHPO Nonsense-mediated mRNA decay prote... | 1105 | 5e-130 | 429 | 29 | 50 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:PomBase. | 3 | P38798 | 1089 | NMD2_YEAST Nonsense-mediated mRNA decay prote... | 109 | 0.000001 | 56.6 | 32 | 58 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005844; C:polysome; IDA:SGD. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IGI:SGD. | 4 | Q9P6R9 | 887 | CWC22_SCHPO Pre-mRNA-splicing factor cwf22 OS... | 127 | 0.005 | 44.7 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase. | 5 | P0CM96 | 831 | CWC22_CRYNJ Pre-mRNA-splicing factor CWC22 OS... | 126 | 0.005 | 44.7 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 6 | P0CM97 | 831 | CWC22_CRYNB Pre-mRNA-splicing factor CWC22 OS... | 126 | 0.005 | 44.7 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 7 | Q03387 | 788 | IF41_WHEAT Eukaryotic initiation factor iso-4... | 74 | 0.011 | 43.5 | 32 | 54 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q6C8C5 | 954 | CWC22_YARLI Pre-mRNA-splicing factor CWC22 OS... | 127 | 0.042 | 41.6 | 27 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 9 | Q04637 | 1599 | IF4G1_HUMAN Eukaryotic translation initiation... | 78 | 0.15 | 40 | 24 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006446; P:regulation of translational initiation; IMP:UniProtKB. | 10 | Q76E23 | 1727 | IF4G1_ARATH Eukaryotic translation initiation... | 98 | 0.17 | 40 | 29 | 50 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 11 | Q6NZJ6 | 1600 | IF4G1_MOUSE Eukaryotic translation initiation... | 78 | 0.2 | 39.7 | 24 | 51 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 12 | O13971 | 775 | SGD1_SCHPO Suppressor of glycerol defect prot... | 134 | 0.27 | 38.9 | 24 | 49 | GO:0005730; C:nucleolus; IDA:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0042274; P:ribosomal small subunit biogenesis; ISS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 13 | Q80XI3 | 1579 | IF4G3_MOUSE Eukaryotic translation initiation... | 97 | 0.34 | 38.9 | 22 | 48 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007128; P:meiotic prophase I; IMP:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0045727; P:positive regulation of translation; IMP:MGI.::GO:0016070; P:RNA metabolic process; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:MGI. | 14 | O43432 | 1585 | IF4G3_HUMAN Eukaryotic translation initiation... | 97 | 0.44 | 38.5 | 22 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; TAS:ProtInc. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0000339; F:RNA cap binding; TAS:ProtInc.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006446; P:regulation of translational initiation; TAS:ProtInc.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 15 | Q9VJ87 | 1330 | CWC22_DROME Pre-mRNA-splicing factor CWC22 ho... | 95 | 0.67 | 37.7 | 25 | 47 | GO:0005681; C:spliceosomal complex; ISS:UniProtKB. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 16 | Q8C5N3 | 908 | CWC22_MOUSE Pre-mRNA-splicing factor CWC22 ho... | 113 | 1.9 | 36.2 | 28 | 50 | GO:0005681; C:spliceosomal complex; ISS:UniProtKB. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 17 | Q8T5T1 | 4835 | MDN1_GIAIN Midasin OS=Giardia intestinalis (G... | 86 | 2.1 | 36.2 | 26 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro. | | | | | | | | | | GO:0006461; P:protein complex assembly; IEA:InterPro. | 18 | Q17336 | 897 | CWC22_CAEEL Pre-mRNA-splicing factor CWC22 ho... | 95 | 2.4 | 35.8 | 23 | 48 | GO:0043073; C:germ cell nucleus; IDA:WormBase.::GO:0000790; C:nuclear chromatin; IDA:WormBase.::GO:0005654; C:nucleoplasm; IDA:WormBase.::GO:0005681; C:spliceosomal complex; ISS:UniProtKB. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007369; P:gastrulation; IMP:WormBase.::GO:0042078; P:germ-line stem cell division; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 19 | Q9HCG8 | 908 | CWC22_HUMAN Pre-mRNA-splicing factor CWC22 ho... | 113 | 2.8 | 35.8 | 28 | 50 | GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA. | | | | | | | | | | GO:0003723; F:RNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; IC:UniProtKB. | 20 | Q6BU84 | 637 | CWC22_DEBHA Pre-mRNA-splicing factor CWC22 OS... | 172 | 3.1 | 35.4 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 21 | A8WT19 | 935 | CWC22_CAEBR Pre-mRNA-splicing factor CWC22 ho... | 95 | 3.4 | 35.4 | 23 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 22 | Q5RA93 | 908 | CWC22_PONAB Pre-mRNA-splicing factor CWC22 ho... | 103 | 3.6 | 35.4 | 29 | 50 | GO:0005681; C:spliceosomal complex; ISS:UniProtKB. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 23 | P0C6U5 | 4421 | R1A_CVHN5 Replicase polyprotein 1a OS=Human c... | 67 | 4.1 | 35.4 | 33 | 52 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 24 | P0C6X4 | 7132 | R1AB_CVHN5 Replicase polyprotein 1ab OS=Human... | 67 | 4.1 | 35.4 | 33 | 52 | GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 25 | P97479 | 2215 | MYO7A_MOUSE Unconventional myosin-VIIa OS=Mus... | 90 | 4.5 | 35 | 28 | 47 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0042470; C:melanosome; IDA:MGI.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0032391; C:photoreceptor connecting cilium; IDA:MGI.::GO:0001917; C:photoreceptor inner segment; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; ISS:UniProtKB.::GO:0032420; C:stereocilium; IDA:MGI.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0060088; P:auditory receptor cell stereocilium organization; IMP:MGI.::GO:0006886; P:intracellular protein transport; IMP:MGI.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0001845; P:phagolysosome assembly; IMP:MGI.::GO:0051904; P:pigment granule transport; IMP:MGI.::GO:0048563; P:post-embryonic organ morphogenesis; IMP:MGI.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0007601; P:visual perception; ISS:UniProtKB. | 26 | Q553R3 | 1377 | IF4G_DICDI Eukaryotic translation initiation ... | 185 | 4.7 | 35 | 20 | 41 | GO:0016281; C:eukaryotic translation initiation factor 4F complex; ISS:dictyBase. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; ISS:dictyBase. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; ISS:dictyBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 27 | Q5ZKA3 | 926 | CWC22_CHICK Pre-mRNA-splicing factor CWC22 ho... | 104 | 6 | 34.7 | 30 | 50 | GO:0005681; C:spliceosomal complex; ISS:UniProtKB. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 28 | Q7RX84 | 1010 | CWC22_NEUCR Pre-mRNA-splicing factor cwc-22 O... | 167 | 6.3 | 34.7 | 22 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 29 | A1ST45 | 880 | IF2_PSYIN Translation initiation factor IF-2 ... | 148 | 6.9 | 34.7 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | A6W1C3 | 422 | HEM1_MARMS Glutamyl-tRNA reductase OS=Marinom... | 150 | 8.9 | 33.9 | 29 | 43 | | | | | | | | | | | GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW. |
