rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
841 | O75881 | 506 | CP7B1_HUMAN 25-hydroxycholesterol 7-alpha-hyd... | 187 | 0.002 | 44.7 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; TAS:ProtInc. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 842 | Q9VRM7 | 543 | CP307_DROME Cytochrome P450 307a1 OS=Drosophi... | 176 | 0.002 | 44.3 | 23 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0042335; P:cuticle development; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0006697; P:ecdysone biosynthetic process; IMP:FlyBase.::GO:0048566; P:embryonic digestive tract development; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007494; P:midgut development; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase. | 843 | P30609 | 507 | CP52G_CANTR Cytochrome P450 52A7 OS=Candida t... | 170 | 0.002 | 44.3 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 844 | Q29527 | 503 | C11B1_PAPHU Cytochrome P450 11B1, mitochondri... | 132 | 0.002 | 44.3 | 26 | 45 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 845 | P43492 | 437 | THCB_RHOER Cytochrome P450 116 OS=Rhodococcus... | 178 | 0.003 | 43.9 | 23 | 39 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 846 | P63723 | 393 | CP143_MYCTU Putative cytochrome P450 143 OS=M... | 172 | 0.003 | 43.9 | 22 | 37 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 847 | P63724 | 393 | CP143_MYCBO Putative cytochrome P450 143 OS=M... | 172 | 0.003 | 43.9 | 22 | 37 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 848 | Q1ZXF3 | 510 | C5172_DICDI Probable cytochrome P450 517A2 OS... | 215 | 0.003 | 43.9 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 849 | P48417 | 536 | CP74_LINUS Allene oxide synthase, chloroplast... | 125 | 0.003 | 43.9 | 26 | 44 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0047987; F:hydroperoxide dehydratase activity; IEA:EC.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0031408; P:oxylipin biosynthetic process; IEA:UniProtKB-KW. | 850 | O44220 | 532 | C12B1_DROAC Cytochrome P450 12b1, mitochondri... | 164 | 0.003 | 43.9 | 22 | 39 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 851 | C4B644 | 403 | CPVDH_PSEAH Vitamin D(3) 25-hydroxylase OS=au... | 102 | 0.003 | 43.5 | 30 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 852 | Q12609 | 483 | STCF_EMENI Probable sterigmatocystin biosynth... | 174 | 0.004 | 43.5 | 22 | 41 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 853 | P79690 | 510 | CP191_CARAU Cytochrome P450 19 type 1 OS=Cara... | 160 | 0.004 | 43.5 | 22 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 854 | O31785 | 405 | PKSS_BACSU Polyketide biosynthesis cytochrome... | 96 | 0.004 | 43.5 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 855 | P14762 | 410 | CPXI_BACME Cytochrome P450(BM-1) OS=Bacillus ... | 171 | 0.005 | 43.1 | 25 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 856 | Q9V6D6 | 553 | CP301_DROME Probable cytochrome P450 301a1, m... | 183 | 0.005 | 43.5 | 23 | 42 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 857 | Q12599 | 408 | NOR2_CYLTO Cytochrome P450 55A3 OS=Cylindroca... | 109 | 0.005 | 42.7 | 30 | 40 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 858 | Q6P7D4 | 462 | CP20A_RAT Cytochrome P450 20A1 OS=Rattus norv... | 190 | 0.006 | 43.1 | 20 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 859 | P63721 | 438 | CP140_MYCTU Putative cytochrome P450 140 OS=M... | 91 | 0.006 | 42.7 | 31 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 860 | P63722 | 438 | CP140_MYCBO Putative cytochrome P450 140 OS=M... | 91 | 0.006 | 42.7 | 31 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 861 | O46491 | 501 | CP7A1_PIG Cholesterol 7-alpha-monooxygenase O... | 220 | 0.006 | 43.1 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; ISS:UniProtKB.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; ISS:UniProtKB. | 862 | P19099 | 503 | C11B2_HUMAN Cytochrome P450 11B2, mitochondri... | 133 | 0.006 | 42.7 | 26 | 46 | GO:0005743; C:mitochondrial inner membrane; IC:BHF-UCL. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IC:BHF-UCL.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IMP:UniProtKB.::GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.::GO:0035865; P:cellular response to potassium ion; IEP:UniProtKB.::GO:0034651; P:cortisol biosynthetic process; IMP:UniProtKB.::GO:0055075; P:potassium ion homeostasis; IMP:BHF-UCL.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:BHF-UCL.::GO:0003091; P:renal water homeostasis; IC:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0055078; P:sodium ion homeostasis; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 863 | Q701P2 | 525 | KO1_GIBIN Ent-kaurene oxidase OS=proliferatum... | 189 | 0.007 | 42.7 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0052617; F:ent-kaur-16-en-19-al oxidase activity; IEA:EC.::GO:0052616; F:ent-kaur-16-en-19-ol oxidase activity; IEA:EC.::GO:0052615; F:ent-kaurene oxidase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010241; P:ent-kaurene oxidation to kaurenoic acid; IEA:EC. | 864 | Q7Y0C8 | 512 | C74A1_ORYSJ Allene oxide synthase 1, chloropl... | 89 | 0.008 | 42.4 | 29 | 45 | GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0047987; F:hydroperoxide dehydratase activity; IEA:EC.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0031408; P:oxylipin biosynthetic process; IEA:UniProtKB-KW. | 865 | Q9VGB4 | 493 | CP132_DROME Probable cytochrome P450 313a2 OS... | 388 | 0.013 | 42 | 20 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 866 | Q8RN03 | 406 | C5C4_AMYOR Cytochrome P450 165C4 OS=Amycolato... | 104 | 0.017 | 41.2 | 33 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 867 | P18327 | 403 | CPXF_STRGO Cytochrome P450-SU2 OS=Streptomyce... | 190 | 0.019 | 41.2 | 24 | 36 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 868 | P63713 | 489 | CP128_MYCTU Putative cytochrome P450 128 OS=M... | 94 | 0.02 | 41.2 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE. | 869 | P63714 | 489 | CP128_MYCBO Putative cytochrome P450 128 OS=M... | 94 | 0.02 | 41.2 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 870 | Q86A22 | 494 | C515A_DICDI Probable cytochrome P450 515A1 OS... | 270 | 0.023 | 41.2 | 21 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 871 | Q60991 | 507 | CP7B1_MOUSE 25-hydroxycholesterol 7-alpha-hyd... | 204 | 0.025 | 40.8 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0007586; P:digestion; TAS:UniProtKB.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:MGI.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:MGI.::GO:0060740; P:prostate gland epithelium morphogenesis; IMP:MGI. |