rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
811 | P79304 | 501 | CP193_PIG Cytochrome P450 19 type III OS=Sus ... | 310 | 0.0003 | 47.4 | 22 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 812 | Q9SAB6 | 497 | C71AI_ARATH Cytochrome P450 71A18 OS=Arabidop... | 205 | 0.0003 | 47 | 21 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 813 | P24453 | 513 | CP1A2_MESAU Cytochrome P450 1A2 OS=Mesocricet... | 171 | 0.0003 | 47 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 814 | Q9D816 | 490 | CP255_MOUSE Cytochrome P450 2C55 OS=Mus muscu... | 178 | 0.0003 | 47 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 815 | Q9V676 | 501 | CP6T3_DROME Probable cytochrome P450 6t3 OS=D... | 172 | 0.0004 | 47 | 24 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 816 | O08447 | 449 | C135A_MYCTU Putative cytochrome P450 135A1 OS... | 190 | 0.0004 | 46.6 | 26 | 39 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 817 | Q54QD0 | 483 | C5174_DICDI Probable cytochrome P450 517A4 OS... | 176 | 0.0004 | 46.6 | 23 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 818 | P18326 | 406 | CPXE_STRGO Cytochrome P450-SU1 OS=Streptomyce... | 66 | 0.0004 | 46.6 | 38 | 52 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 819 | Q6UW02 | 462 | CP20A_HUMAN Cytochrome P450 20A1 OS=Homo sapi... | 166 | 0.0004 | 46.6 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 820 | Q9VYQ5 | 536 | CP318_DROME Probable cytochrome P450 318a1 OS... | 431 | 0.0005 | 46.6 | 19 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 821 | P18125 | 503 | CP7A1_RAT Cholesterol 7-alpha-monooxygenase O... | 222 | 0.0006 | 46.2 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0071397; P:cellular response to cholesterol; IDA:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; IDA:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB. | 822 | P58045 | 497 | C71AE_ARATH Cytochrome P450 71A14 OS=Arabidop... | 260 | 0.0006 | 46.2 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 823 | Q94IW5 | 490 | C90D2_ORYSJ Cytochrome P450 90D2 OS=Oryza sat... | 208 | 0.0006 | 46.2 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IEA:UniProtKB-KW. | 824 | P33271 | 405 | CPXK_SACEN Cytochrome P450 107B1 OS=Saccharop... | 116 | 0.0006 | 45.8 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 825 | Q92087 | 518 | CP19A_ORYLA Cytochrome P450 19A1 OS=Oryzias l... | 198 | 0.0006 | 46.2 | 22 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 826 | Q29626 | 500 | PTGIS_BOVIN Prostacyclin synthase OS=Bos taur... | 186 | 0.0006 | 46.2 | 26 | 47 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB. | 827 | Q54WB9 | 519 | C513D_DICDI Probable cytochrome P450 513D1 OS... | 104 | 0.0007 | 46.2 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 828 | Q28827 | 445 | CP11A_RABIT Cholesterol side-chain cleavage e... | 146 | 0.0007 | 45.8 | 28 | 41 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 829 | O93299 | 491 | CP2K3_ONCMY Cytochrome P450 2K3 OS=Oncorhynch... | 194 | 0.0007 | 45.8 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 830 | Q9FH66 | 497 | C71AG_ARATH Cytochrome P450 71A16 OS=Arabidop... | 180 | 0.0007 | 45.8 | 24 | 42 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 831 | Q9AR74 | 506 | TCMO_RUTGR Trans-cinnamate 4-monooxygenase OS... | 161 | 0.0008 | 45.8 | 23 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:EC. | | | | | | | | | | | 832 | P82713 | 538 | CP392_DROME Probable cytochrome P450 309a2 OS... | 163 | 0.0008 | 45.8 | 25 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 833 | Q9VS78 | 478 | CP316_DROME Probable cytochrome P450 316a1 OS... | 447 | 0.0008 | 45.4 | 21 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 834 | Q92111 | 524 | CP19A_ICTPU Cytochrome P450 19A1 OS=Ictalurus... | 471 | 0.001 | 45.4 | 23 | 38 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 835 | O46512 | 503 | CP19A_HORSE Cytochrome P450 19A1 OS=Equus cab... | 167 | 0.001 | 45.4 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 836 | Q1ZXN4 | 524 | C519C_DICDI Probable cytochrome P450 519C1 OS... | 216 | 0.002 | 44.7 | 21 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 837 | Q64505 | 503 | CP7A1_MOUSE Cholesterol 7-alpha-monooxygenase... | 194 | 0.002 | 44.7 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; ISS:UniProtKB.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070859; P:positive regulation of bile acid biosynthetic process; TAS:BHF-UCL. | 838 | P22680 | 504 | CP7A1_HUMAN Cholesterol 7-alpha-monooxygenase... | 215 | 0.002 | 44.7 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 839 | Q16647 | 500 | PTGIS_HUMAN Prostacyclin synthase OS=Homo sap... | 186 | 0.002 | 44.7 | 25 | 47 | GO:0005901; C:caveola; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; NAS:UniProtKB.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; IEP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; IDA:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 840 | P15538 | 503 | C11B1_HUMAN Cytochrome P450 11B1, mitochondri... | 132 | 0.002 | 44.7 | 26 | 45 | GO:0005743; C:mitochondrial inner membrane; TAS:BHF-UCL.::GO:0005739; C:mitochondrion; IEA:InterPro. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IC:BHF-UCL.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IMP:UniProtKB.::GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.::GO:0035865; P:cellular response to potassium ion; IEP:UniProtKB.::GO:0034651; P:cortisol biosynthetic process; IMP:UniProtKB.::GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.::GO:0006955; P:immune response; TAS:BHF-UCL.::GO:0008217; P:regulation of blood pressure; IMP:BHF-UCL.::GO:0006950; P:response to stress; TAS:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 841 | O75881 | 506 | CP7B1_HUMAN 25-hydroxycholesterol 7-alpha-hyd... | 187 | 0.002 | 44.7 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; TAS:ProtInc. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. |