| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P54781 | 538 | ERG5_YEAST Cytochrome P450 61 OS=Saccharomyce... | 542 | 0 | 587 | 54 | 68 | GO:0005783; C:endoplasmic reticulum; IDA:SGD. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:SGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IDA:SGD. | 2 | O13820 | 543 | ERG5_SCHPO Cytochrome P450 61 OS=Schizosaccha... | 491 | 0 | 567 | 55 | 70 | GO:0005783; C:endoplasmic reticulum; ISS:PomBase. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; ISS:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.::GO:0090002; P:establishment of protein localization in plasma membrane; IMP:PomBase.::GO:0071210; P:protein insertion into membrane raft; IMP:PomBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 3 | Q55EK2 | 532 | C524A_DICDI Probable cytochrome P450 524A1 OS... | 495 | 4e-78 | 261 | 33 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 4 | O64697 | 495 | C7101_ARATH Cytochrome P450 710A1 OS=Arabidop... | 513 | 5e-77 | 258 | 33 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 5 | O64698 | 499 | C7102_ARATH Cytochrome P450 710A2 OS=Arabidop... | 511 | 5e-69 | 236 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 6 | Q9ZV28 | 493 | C7104_ARATH Cytochrome P450 710A1 OS=Arabidop... | 487 | 9e-67 | 230 | 31 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 7 | P79739 | 492 | CP26A_DANRE Cytochrome P450 26A1 OS=Danio rer... | 470 | 8e-27 | 117 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 8 | O43174 | 497 | CP26A_HUMAN Cytochrome P450 26A1 OS=Homo sapi... | 402 | 2e-23 | 107 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; NAS:BHF-UCL.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.::GO:0001972; F:retinoic acid binding; IDA:BHF-UCL. | | | | | | | | | | GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; TAS:BHF-UCL.::GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 9 | O55127 | 497 | CP26A_MOUSE Cytochrome P450 26A1 OS=Mus muscu... | 403 | 2e-23 | 107 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0007417; P:central nervous system development; IMP:MGI.::GO:0014032; P:neural crest cell development; IGI:MGI.::GO:0048384; P:retinoic acid receptor signaling pathway; IGI:MGI. | 10 | Q8K4D6 | 507 | CP4X1_RAT Cytochrome P450 4X1 OS=Rattus norve... | 168 | 3e-22 | 103 | 30 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 11 | Q6V0L0 | 522 | CP26C_HUMAN Cytochrome P450 26C1 OS=Homo sapi... | 421 | 6e-22 | 102 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.::GO:0001972; F:retinoic acid binding; IDA:BHF-UCL. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.::GO:0007417; P:central nervous system development; ISS:BHF-UCL.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; NAS:BHF-UCL.::GO:0014032; P:neural crest cell development; ISS:BHF-UCL.::GO:0048284; P:organelle fusion; ISS:BHF-UCL.::GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 12 | Q9PUB4 | 492 | CP26A_CHICK Cytochrome P450 26A1 OS=Gallus ga... | 403 | 7e-21 | 99.4 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0034653; P:retinoic acid catabolic process; IDA:MGI. | 13 | Q08D50 | 511 | CP26B_XENTR Cytochrome P450 26B1 OS=Xenopus t... | 399 | 1e-20 | 99 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 14 | O93323 | 492 | CP26A_XENLA Cytochrome P450 26A1 OS=Xenopus l... | 400 | 2e-20 | 97.8 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 15 | Q86W10 | 505 | CP4Z1_HUMAN Cytochrome P450 4Z1 OS=Homo sapie... | 164 | 5e-20 | 97.1 | 30 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 16 | Q9VS79 | 463 | CP4D8_DROME Cytochrome P450 4d8 OS=Drosophila... | 441 | 5e-20 | 96.3 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 17 | Q6WKZ0 | 494 | C7D94_MENGR Cytochrome P450 71D94 OS=Mentha g... | 357 | 1e-19 | 95.5 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 18 | Q02928 | 519 | CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi... | 166 | 2e-19 | 95.5 | 33 | 51 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 19 | Q9SAA9 | 488 | CP511_ARATH Sterol 14-demethylase OS=Arabidop... | 480 | 2e-19 | 94.7 | 23 | 40 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; TAS:TAIR. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IMP:TAIR. | 20 | Q8SPK0 | 504 | CP4AP_PIG Cytochrome P450 4A25 OS=Sus scrofa ... | 165 | 2e-19 | 94.7 | 32 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 21 | P14580 | 510 | CP4A6_RABIT Cytochrome P450 4A6 OS=Oryctolagu... | 166 | 3e-19 | 94.7 | 33 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 22 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 166 | 4e-19 | 94.4 | 32 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 23 | P14579 | 511 | CP4A5_RABIT Cytochrome P450 4A5 OS=Oryctolagu... | 166 | 5e-19 | 94 | 32 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 24 | Q9VXY0 | 495 | CP4S3_DROME Probable cytochrome P450 4s3 OS=D... | 212 | 5e-19 | 93.6 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 25 | Q9GJX5 | 504 | CP4AL_PIG Taurochenodeoxycholic 6 alpha-hydro... | 165 | 6e-19 | 93.6 | 32 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC. | | | | | | | | | | | 26 | Q8SPK1 | 504 | CP4AO_PIG Cytochrome P450 4A24 OS=Sus scrofa ... | 165 | 6e-19 | 93.6 | 32 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 27 | Q9VYY4 | 574 | C4G15_DROME Cytochrome P450 4g15 OS=Drosophil... | 199 | 7e-19 | 93.6 | 27 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 28 | P10611 | 510 | CP4A4_RABIT Cytochrome P450 4A4 OS=Oryctolagu... | 166 | 1e-18 | 92.8 | 32 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 29 | Q59990 | 444 | CP120_SYNY3 Putative cytochrome P450 120 OS=S... | 438 | 1e-18 | 92 | 23 | 41 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 30 | Q50EK1 | 493 | C16B1_PICSI Cytochrome P450 716B1 OS=Picea si... | 264 | 1e-18 | 92.4 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 31 | Q8N118 | 509 | CP4X1_HUMAN Cytochrome P450 4X1 OS=Homo sapie... | 166 | 1e-18 | 92.4 | 30 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
