rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q9V4U7 | 509 | C6A14_DROME Probable cytochrome P450 6a14 OS=... | 100 | 0.18 | 38.1 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 242 | Q9GQM9 | 503 | CP6L1_BLAGE Cytochrome P450 6l1 OS=Blattella ... | 155 | 0.19 | 37.7 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 243 | Q07973 | 514 | CP24A_HUMAN 1,25-dihydroxyvitamin D(3) 24-hyd... | 321 | 0.19 | 37.7 | 19 | 38 | GO:0005743; C:mitochondrial inner membrane; TAS:Reactome. | | | | | | | | | | GO:0030342; F:1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; TAS:UniProtKB. | | | | | | | | | | GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0042369; P:vitamin D catabolic process; NAS:BHF-UCL.::GO:0070561; P:vitamin D receptor signaling pathway; IEP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 244 | O73853 | 514 | CP17A_ICTPU Steroid 17-alpha-hydroxylase/17,2... | 74 | 0.2 | 37.7 | 30 | 50 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 245 | P23296 | 381 | CPXG_STRSQ Cytochrome P450 105C1 OS=Streptomy... | 160 | 0.2 | 37.7 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 246 | Q2LA59 | 492 | CP21A_LYNLY Steroid 21-hydroxylase OS=Lynx ly... | 327 | 0.22 | 37.7 | 22 | 36 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 247 | P93703 | 535 | C71C3_MAIZE Cytochrome P450 71C3 OS=Zea mays ... | 112 | 0.22 | 37.7 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 248 | D5JBX1 | 496 | GAO_BARSP Germacrene A oxidase OS=Barnadesia ... | 95 | 0.22 | 37.7 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 249 | Q9DBG1 | 533 | CP27A_MOUSE Sterol 26-hydroxylase, mitochondr... | 271 | 0.23 | 37.7 | 23 | 41 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 250 | P98183 | 495 | C71DC_CATRO Tabersonine 16-hydroxylase OS=Cat... | 248 | 0.23 | 37.7 | 23 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050594; F:tabersonine 16-hydroxylase activity; IEA:EC. | | | | | | | | | | | 251 | D5J9U8 | 488 | GAO_LACSA Germacrene A oxidase OS=Lactuca sat... | 80 | 0.23 | 37.7 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 252 | P78329 | 520 | CP4F2_HUMAN Leukotriene-B(4) omega-hydroxylas... | 101 | 0.23 | 37.7 | 26 | 44 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IDA:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0052872; F:tocotrienol omega-hydroxylase activity; IDA:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IMP:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; IMP:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; IMP:UniProtKB.::GO:0032304; P:negative regulation of icosanoid secretion; IMP:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0042360; P:vitamin E metabolic process; IDA:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; IMP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 253 | Q12573 | 519 | CP52W_CANAP Cytochrome P450 52E2 OS=Candida a... | 78 | 0.24 | 37.7 | 33 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 254 | P10635 | 497 | CP2D6_HUMAN Cytochrome P450 2D6 OS=Homo sapie... | 78 | 0.24 | 37.7 | 33 | 51 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0009804; P:coumarin metabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0033076; P:isoquinoline alkaloid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0051100; P:negative regulation of binding; IDA:BHF-UCL.::GO:0090350; P:negative regulation of cellular organofluorine metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL. | 255 | Q9NGX9 | 489 | CP302_DROME Cytochrome P450 302a1, mitochondr... | 259 | 0.25 | 37.7 | 22 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042767; F:ecdysteroid 22-hydroxylase activity; IDA:FlyBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0008362; P:chitin-based embryonic cuticle biosynthetic process; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0006697; P:ecdysone biosynthetic process; IDA:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007494; P:midgut development; IMP:FlyBase. | 256 | Q2XNC9 | 497 | CP2D6_PANPA Cytochrome P450 2D6 OS=Pan panisc... | 78 | 0.25 | 37.7 | 33 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 257 | Q09736 | 495 | CP51_SCHPO Lanosterol 14-alpha demethylase er... | 126 | 0.25 | 37.4 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008398; F:sterol 14-demethylase activity; ISS:PomBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IEP:PomBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 258 | O44220 | 532 | C12B1_DROAC Cytochrome P450 12b1, mitochondri... | 88 | 0.79 | 35.8 | 30 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 259 | Q3LFU0 | 516 | CP1A1_BALAC Cytochrome P450 1A1 OS=Balaenopte... | 71 | 0.26 | 37.4 | 32 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 260 | P51663 | 503 | C11B1_SHEEP Cytochrome P450 11B1, mitochondri... | 247 | 0.27 | 37.4 | 24 | 42 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 261 | O49340 | 497 | C71AC_ARATH Cytochrome P450 71A12 OS=Arabidop... | 127 | 0.27 | 37.4 | 24 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009617; P:response to bacterium; IEP:TAIR. | 262 | P16141 | 538 | CP52D_CANMA Cytochrome P450 52A4 OS=Candida m... | 84 | 0.29 | 37.4 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 263 | Q3LFT9 | 516 | CP1A2_BALAC Cytochrome P450 1A2 OS=Balaenopte... | 282 | 0.3 | 37.4 | 20 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 264 | Q9LTM3 | 502 | C71BK_ARATH Cytochrome P450 71B20 OS=Arabidop... | 76 | 0.3 | 37.4 | 29 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 265 | P33274 | 524 | CP4F1_RAT Cytochrome P450 4F1 OS=Rattus norve... | 102 | 0.31 | 37.4 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0050544; F:arachidonic acid binding; IDA:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IDA:RGD.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:RGD. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 266 | C0SJS4 | 476 | C71AJ_APIGR Psoralen synthase OS=Apium graveo... | 73 | 0.31 | 37.4 | 30 | 52 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 267 | P48416 | 545 | CP10_LYMST Cytochrome P450 10 OS=Lymnaea stag... | 221 | 0.31 | 37.4 | 22 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 268 | Q2XNC8 | 497 | CP2D6_PANTR Cytochrome P450 2D6 OS=Pan troglo... | 78 | 0.32 | 37.4 | 33 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 269 | Q9LIP3 | 500 | C71BY_ARATH Cytochrome P450 71B37 OS=Arabidop... | 112 | 0.32 | 37.4 | 28 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 270 | Q9FMY1 | 559 | C86B1_ARATH Cytochrome P450 86B1 OS=Arabidops... | 324 | 0.33 | 37.4 | 20 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0010345; P:suberin biosynthetic process; IMP:TAIR.::GO:0042761; P:very long-chain fatty acid biosynthetic process; IMP:TAIR. | 271 | P30099 | 510 | C11B2_RAT Cytochrome P450 11B2, mitochondrial... | 256 | 0.35 | 37 | 21 | 41 | GO:0030425; C:dendrite; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:RGD. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IDA:RGD.::GO:0071260; P:cellular response to mechanical stimulus; IEP:RGD.::GO:0031670; P:cellular response to nutrient; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IEP:RGD.::GO:0051365; P:cellular response to potassium ion starvation; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD. |