| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q10362 | 859 | SET3_SCHPO SET domain-containing protein 3 OS... | 387 | 8e-22 | 105 | 26 | 43 | GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0034967; C:Set3 complex; IDA:PomBase. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; TAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q3UG20 | 1868 | MLL5_MOUSE Histone-lysine N-methyltransferase... | 77 | 0.000000003 | 65.1 | 38 | 56 | GO:0070688; C:MLL5-L complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; ISS:BHF-UCL.::GO:0006306; P:DNA methylation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0042119; P:neutrophil activation; IMP:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q8IZD2 | 1858 | MLL5_HUMAN Histone-lysine N-methyltransferase... | 77 | 0.000000004 | 64.7 | 38 | 56 | GO:0070688; C:MLL5-L complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IDA:BHF-UCL.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0042119; P:neutrophil activation; ISS:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; ISS:UniProtKB.::GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | P42948 | 560 | SET4_YEAST SET domain-containing protein 4 OS... | 107 | 0.000000001 | 65.5 | 38 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 5 | P36124 | 751 | SET3_YEAST SET domain-containing protein 3 OS... | 73 | 0.0000004 | 57.8 | 37 | 55 | GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0034967; C:Set3 complex; IDA:SGD. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0045835; P:negative regulation of meiosis; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q9C0A6 | 1442 | SETD5_HUMAN SET domain-containing protein 5 O... | 101 | 0.00000003 | 61.6 | 28 | 53 | | | | | | | | | | | | | | | | | | | | | | 7 | Q5XJV7 | 1441 | SETD5_MOUSE SET domain-containing protein 5 O... | 101 | 0.00000003 | 61.6 | 28 | 53 | | | | | | | | | | | | | | | | | | | | | | 8 | Q9NR48 | 2969 | ASH1L_HUMAN Histone-lysine N-methyltransferas... | 64 | 0.0000005 | 57.8 | 38 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005923; C:tight junction; TAS:ProtInc. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006323; P:DNA packaging; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 9 | Q99MY8 | 2958 | ASH1L_MOUSE Histone-lysine N-methyltransferas... | 64 | 0.0000005 | 57.8 | 38 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q9VW15 | 2226 | ASH1_DROME Histone-lysine N-methyltransferase... | 62 | 0.00002 | 52.4 | 35 | 47 | GO:0005634; C:nucleus; IC:FlyBase.::GO:0035327; C:transcriptionally active chromatin; IMP:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); NAS:FlyBase.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); NAS:FlyBase.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0018991; P:oviposition; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q4V9H5 | 1015 | P20L1_RAT PHD finger protein 20-like protein ... | 147 | 0.001 | 46.6 | 25 | 40 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q6BM04 | 731 | SET2_DEBHA Histone-lysine N-methyltransferase... | 67 | 0.003 | 45.4 | 31 | 54 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q8CCJ9 | 1013 | P20L1_MOUSE PHD finger protein 20-like protei... | 147 | 0.004 | 44.7 | 24 | 40 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 14 | Q9UMN6 | 2715 | MLL4_HUMAN Histone-lysine N-methyltransferase... | 133 | 0.009 | 43.9 | 21 | 46 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | O08550 | 2713 | MLL4_MOUSE Histone-lysine N-methyltransferase... | 133 | 0.011 | 43.5 | 21 | 46 | GO:0035097; C:histone methyltransferase complex; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016458; P:gene silencing; IMP:MGI.::GO:0080182; P:histone H3-K4 trimethylation; IMP:MGI.::GO:0009994; P:oocyte differentiation; IMP:MGI.::GO:0001541; P:ovarian follicle development; IMP:MGI.::GO:0030728; P:ovulation; IMP:MGI.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q1L8U8 | 1436 | STB1A_DANRE Histone-lysine N-methyltransferas... | 60 | 0.013 | 43.1 | 32 | 50 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | P36106 | 594 | BYE1_YEAST Transcription factor BYE1 OS=Sacch... | 61 | 0.019 | 42.4 | 26 | 51 | GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | A6ZZW1 | 594 | BYE1_YEAS7 Transcription factor BYE1 OS=Sacch... | 61 | 0.02 | 42.4 | 26 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q5F3P8 | 2008 | SET1B_CHICK Histone-lysine N-methyltransferas... | 58 | 0.022 | 42.4 | 36 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q09698 | 607 | YA27_SCHPO Uncharacterized protein C2F7.07c O... | 141 | 0.025 | 42 | 30 | 41 | GO:0032221; C:Rpd3S complex; IDA:PomBase.::GO:0005819; C:spindle; IDA:PomBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016575; P:histone deacetylation; ISS:PomBase. | 21 | O14026 | 798 | SET2_SCHPO Histone-lysine N-methyltransferase... | 65 | 0.028 | 42 | 29 | 48 | GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:PomBase. | | | | | | | | | | GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:PomBase. | 22 | Q9UPS6 | 1923 | SET1B_HUMAN Histone-lysine N-methyltransferas... | 58 | 0.033 | 42 | 36 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q5ASA5 | 980 | SET2_EMENI Histone-lysine N-methyltransferase... | 65 | 0.034 | 42 | 25 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | P34544 | 1300 | MET2_CAEEL Probable histone-lysine N-methyltr... | 85 | 0.035 | 42 | 25 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007276; P:gamete generation; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0010452; P:histone H3-K36 methylation; IMP:WormBase.::GO:0051567; P:histone H3-K9 methylation; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase. | 25 | Q8CFT2 | 1985 | SET1B_MOUSE Histone-lysine N-methyltransferas... | 58 | 0.037 | 42 | 36 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | Q6CXP5 | 702 | SET2_KLULA Histone-lysine N-methyltransferase... | 65 | 0.037 | 41.6 | 28 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q6C5G5 | 768 | SET2_YARLI Histone-lysine N-methyltransferase... | 65 | 0.065 | 40.8 | 25 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q8BRH4 | 4903 | MLL3_MOUSE Histone-lysine N-methyltransferase... | 135 | 0.072 | 40.8 | 24 | 46 | GO:0035097; C:histone methyltransferase complex; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q1DU03 | 1003 | SET2_COCIM Histone-lysine N-methyltransferase... | 65 | 0.074 | 40.8 | 25 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q59XV0 | 844 | SET2_CANAL Histone-lysine N-methyltransferase... | 65 | 0.097 | 40.4 | 31 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | A8MW92 | 1017 | P20L1_HUMAN PHD finger protein 20-like protei... | 151 | 0.11 | 40 | 23 | 38 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
