| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12324 | 675 | YVC1_YEAST Calcium channel YVC1 OS=Saccharomy... | 377 | 8e-18 | 91.7 | 26 | 45 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005227; F:calcium activated cation channel activity; IDA:SGD.::GO:0005262; F:calcium channel activity; IDA:SGD.::GO:0005267; F:potassium channel activity; IDA:SGD.::GO:0005272; F:sodium channel activity; IDA:SGD.::GO:0005244; F:voltage-gated ion channel activity; IDA:SGD. | | | | | | | | | | GO:0030003; P:cellular cation homeostasis; IDA:SGD. | 2 | P34586 | 1027 | TRPL_CAEEL Transient-receptor-potential-like ... | 443 | 0.000000000002 | 74.3 | 24 | 41 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:InterPro. | | | | | | | | | | | 3 | Q9QX29 | 975 | TRPC5_MOUSE Short transient receptor potentia... | 405 | 0.0000000004 | 67 | 23 | 39 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL. | | | | | | | | | | | 4 | O62852 | 974 | TRPC5_RABIT Short transient receptor potentia... | 405 | 0.0000000004 | 67 | 23 | 39 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q9UL62 | 973 | TRPC5_HUMAN Short transient receptor potentia... | 405 | 0.0000000005 | 66.6 | 23 | 39 | GO:0034704; C:calcium channel complex; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. | 6 | Q9R283 | 1170 | TRPC2_RAT Short transient receptor potential ... | 423 | 0.000000006 | 63.5 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro. | | | | | | | | | | GO:0000012; P:single strand break repair; IEA:InterPro. | 7 | Q9R244 | 1172 | TRPC2_MOUSE Short transient receptor potentia... | 423 | 0.00000005 | 60.5 | 22 | 40 | GO:0032590; C:dendrite membrane; IMP:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IDA:MGI.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:MGI.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019992; F:diacylglycerol binding; IMP:MGI.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IPI:MGI.::GO:0008050; P:female courtship behavior; IMP:MGI.::GO:0002121; P:inter-male aggressive behavior; IMP:MGI.::GO:0048047; P:mating behavior, sex discrimination; IMP:MGI.::GO:0019236; P:response to pheromone; IMP:MGI.::GO:0000012; P:single strand break repair; IEA:InterPro.::GO:0002124; P:territorial aggressive behavior; IMP:MGI. | 8 | P79100 | 979 | TRPC4_BOVIN Short transient receptor potentia... | 238 | 0.0000002 | 58.5 | 24 | 40 | | | | | | | | | | | | | | | | | | | | | | 9 | Q9QUQ5 | 974 | TRPC4_MOUSE Short transient receptor potentia... | 238 | 0.0000002 | 58.5 | 24 | 40 | GO:0005901; C:caveola; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IMP:MGI. | | | | | | | | | | GO:0014051; P:gamma-aminobutyric acid secretion; IMP:MGI. | 10 | Q9UBN4 | 977 | TRPC4_HUMAN Short transient receptor potentia... | 238 | 0.0000002 | 58.5 | 24 | 40 | GO:0016323; C:basolateral plasma membrane; IDA:BHF-UCL.::GO:0034704; C:calcium channel complex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0030863; C:cortical cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0045296; F:cadherin binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IMP:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0070509; P:calcium ion import; IDA:BHF-UCL. | 11 | O35119 | 977 | TRPC4_RAT Short transient receptor potential ... | 238 | 0.0000006 | 57 | 23 | 40 | GO:0005887; C:integral to plasma membrane; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0051924; P:regulation of calcium ion transport; IMP:RGD. | 12 | Q9VJJ7 | 1128 | TRPG_DROME Transient receptor potential-gamma... | 429 | 0.000005 | 53.9 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016028; C:rhabdomere; IDA:UniProtKB. | | | | | | | | | | GO:0005262; F:calcium channel activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050908; P:detection of light stimulus involved in visual perception; ISS:UniProtKB. | 13 | A8DYE2 | 2023 | TRPCG_DROME Transient receptor potential cati... | 235 | 0.00006 | 50.4 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.::GO:0046873; F:metal ion transmembrane transporter activity; IDA:FlyBase. | | | | | | | | | | GO:0016049; P:cell growth; IMP:FlyBase.::GO:0070838; P:divalent metal ion transport; IDA:FlyBase.::GO:0010960; P:magnesium ion homeostasis; IMP:FlyBase.::GO:0007005; P:mitochondrion organization; IMP:FlyBase.::GO:0055069; P:zinc ion homeostasis; IMP:FlyBase. | 14 | Q8R4D5 | 1104 | TRPM8_MOUSE Transient receptor potential cati... | 200 | 0.0006 | 47 | 30 | 45 | GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.::GO:0051289; P:protein homotetramerization; IDA:MGI.::GO:0070207; P:protein homotrimerization; IDA:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI. | 15 | Q8R455 | 1104 | TRPM8_RAT Transient receptor potential cation... | 372 | 0.0008 | 46.6 | 24 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0009409; P:response to cold; IDA:RGD. | 16 | O94759 | 1503 | TRPM2_HUMAN Transient receptor potential cati... | 262 | 0.001 | 46.2 | 21 | 40 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047631; F:ADP-ribose diphosphatase activity; IEA:EC.::GO:0005262; F:calcium channel activity; TAS:ProtInc.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | Q7Z2W7 | 1104 | TRPM8_HUMAN Transient receptor potential cati... | 221 | 0.001 | 46.2 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 18 | Q9WVC5 | 862 | TRPC7_MOUSE Short transient receptor potentia... | 287 | 0.002 | 45.4 | 21 | 38 | GO:0016021; C:integral to membrane; IC:MGI.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0006828; P:manganese ion transport; IDA:MGI. | 19 | Q91YD4 | 1507 | TRPM2_MOUSE Transient receptor potential cati... | 250 | 0.003 | 45.1 | 21 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0047631; F:ADP-ribose diphosphatase activity; IEA:EC.::GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0005384; F:manganese ion transmembrane transporter activity; IDA:MGI.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033194; P:response to hydroperoxide; IDA:MGI. | 20 | O62826 | 432 | TRPC2_BOVIN Short transient receptor potentia... | 157 | 0.005 | 43.5 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q9Y210 | 931 | TRPC6_HUMAN Short transient receptor potentia... | 389 | 0.016 | 42.4 | 21 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IDA:MGI. | 22 | Q61143 | 930 | TRPC6_MOUSE Short transient receptor potentia... | 264 | 0.02 | 42 | 21 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0036057; C:slit diaphragm; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0015279; F:store-operated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:MGI. | 23 | Q9HCX4 | 862 | TRPC7_HUMAN Short transient receptor potentia... | 287 | 0.026 | 41.6 | 20 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome. | 24 | P48994 | 1124 | TRPL_DROME Transient-receptor-potential-like ... | 290 | 0.033 | 41.2 | 20 | 39 | GO:0016027; C:inaD signaling complex; IPI:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0007589; P:body fluid secretion; IMP:FlyBase.::GO:0019722; P:calcium-mediated signaling; IMP:FlyBase.::GO:0071454; P:cellular response to anoxia; IGI:FlyBase.::GO:0050908; P:detection of light stimulus involved in visual perception; ISS:UniProtKB. | 25 | Q9JMI9 | 836 | TRPC3_RAT Short transient receptor potential ... | 171 | 0.046 | 40.8 | 21 | 37 | | | | | | | | | | | GO:0005227; F:calcium activated cation channel activity; IDA:RGD.::GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q9QZC1 | 836 | TRPC3_MOUSE Short transient receptor potentia... | 171 | 0.046 | 40.8 | 21 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | Q13507 | 836 | TRPC3_HUMAN Short transient receptor potentia... | 291 | 0.047 | 40.8 | 21 | 37 | GO:0005887; C:integral to plasma membrane; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007602; P:phototransduction; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:UniProtKB.::GO:0033198; P:response to ATP; IDA:UniProtKB.::GO:0051592; P:response to calcium ion; IDA:UniProtKB. | 28 | Q24270 | 2516 | CAC1D_DROME Voltage-dependent calcium channel... | 148 | 0.075 | 40.4 | 28 | 47 | GO:0016324; C:apical plasma membrane; IDA:FlyBase.::GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005891; C:voltage-gated calcium channel complex; NAS:FlyBase. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0042045; P:epithelial fluid transport; IDA:FlyBase.::GO:0006936; P:muscle contraction; TAS:FlyBase. | 29 | P15381 | 2171 | CAC1C_RABIT Voltage-dependent L-type calcium ... | 167 | 0.33 | 38.1 | 26 | 45 | GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; ISS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB. | 30 | Q13936 | 2221 | CAC1C_HUMAN Voltage-dependent L-type calcium ... | 167 | 0.34 | 38.1 | 26 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 31 | Q01815 | 2139 | CAC1C_MOUSE Voltage-dependent L-type calcium ... | 167 | 0.37 | 38.1 | 26 | 45 | GO:0002095; C:caveolar macromolecular signaling complex; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0030315; C:T-tubule; TAS:MGI.::GO:0005891; C:voltage-gated calcium channel complex; TAS:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005245; F:voltage-gated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007628; P:adult walking behavior; IGI:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IMP:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0030252; P:growth hormone secretion; IDA:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0046620; P:regulation of organ growth; IMP:MGI.::GO:0019229; P:regulation of vasoconstriction; IMP:MGI.::GO:0060083; P:smooth muscle contraction involved in micturition; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. |
