| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9XTI0 | 299 | 3HIDH_CAEEL Probable 3-hydroxyisobutyrate deh... | 182 | 8e-19 | 86.3 | 36 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 2 | Q9SUC0 | 347 | 3HIDH_ARATH Probable 3-hydroxyisobutyrate deh... | 183 | 1e-18 | 85.9 | 38 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 3 | Q54CX6 | 321 | 3HIDH_DICDI Probable 3-hydroxyisobutyrate deh... | 184 | 7e-16 | 78.2 | 35 | 53 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 4 | Q99L13 | 335 | 3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenas... | 169 | 0.00000000000002 | 73.9 | 34 | 49 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 5 | P28811 | 298 | MMSB_PSEAE 3-hydroxyisobutyrate dehydrogenase... | 177 | 0.00000000000008 | 72 | 33 | 49 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 6 | Q9V8M5 | 324 | 3HIDH_DROME Probable 3-hydroxyisobutyrate deh... | 181 | 0.0000000000001 | 71.6 | 36 | 48 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 7 | P29266 | 335 | 3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase,... | 173 | 0.0000000000002 | 71.2 | 34 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 8 | Q5R5E7 | 336 | 3HIDH_PONAB 3-hydroxyisobutyrate dehydrogenas... | 168 | 0.0000000000004 | 70.1 | 33 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 9 | P31937 | 336 | 3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenas... | 168 | 0.0000000000005 | 70.1 | 33 | 48 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; NAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; NAS:UniProtKB. | 10 | Q2HJD7 | 336 | 3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenas... | 168 | 0.000000000006 | 67 | 32 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 11 | P0ABQ2 | 294 | GARR_ECOLI 2-hydroxy-3-oxopropionate reductas... | 182 | 0.0000000002 | 62.4 | 33 | 46 | | | | | | | | | | | GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0019582; P:D-galactarate catabolic process; IDA:EcoCyc.::GO:0042838; P:D-glucarate catabolic process; IDA:EcoCyc.::GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 12 | P0ABQ3 | 294 | GARR_ECOL6 2-hydroxy-3-oxopropionate reductas... | 182 | 0.0000000002 | 62.4 | 33 | 46 | | | | | | | | | | | GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IEA:EC.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 13 | P63935 | 294 | MMSB_MYCTU Probable 3-hydroxyisobutyrate dehy... | 171 | 0.000000001 | 60.1 | 35 | 43 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 14 | P63936 | 294 | MMSB_MYCBO Probable 3-hydroxyisobutyrate dehy... | 171 | 0.000000001 | 60.1 | 35 | 43 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 15 | Q0QLF5 | 301 | HMGD_EUBBA 2-(hydroxymethyl)glutarate dehydro... | 171 | 0.0000003 | 53.1 | 32 | 44 | | | | | | | | | | | GO:0043718; F:2-hydroxymethylglutarate dehydrogenase activity; IDA:UniProtKB.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 16 | Q9L7S0 | 298 | YIHU_SALTY Uncharacterized oxidoreductase yih... | 176 | 0.000004 | 50.1 | 30 | 40 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 17 | O34948 | 288 | YKWC_BACSU Uncharacterized oxidoreductase ykw... | 171 | 0.00001 | 48.5 | 30 | 42 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 18 | P77161 | 292 | GLXR_ECOLI 2-hydroxy-3-oxopropionate reductas... | 170 | 0.00001 | 48.1 | 29 | 42 | | | | | | | | | | | GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0009442; P:allantoin assimilation pathway; IEP:EcoCyc.::GO:0009436; P:glyoxylate catabolic process; IMP:EcoCyc.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 19 | Q55702 | 290 | Y229_SYNY3 Uncharacterized oxidoreductase slr... | 197 | 0.00003 | 47.4 | 28 | 44 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 20 | P0A9V9 | 298 | YIHU_SHIFL Uncharacterized oxidoreductase yih... | 176 | 0.00004 | 47 | 28 | 41 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 21 | P0A9V8 | 298 | YIHU_ECOLI Uncharacterized oxidoreductase yih... | 176 | 0.00004 | 47 | 28 | 41 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0047577; F:4-hydroxybutyrate dehydrogenase activity; IDA:EcoCyc.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0009407; P:toxin catabolic process; IMP:EcoCyc.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 22 | O33730 | 291 | Y1503_SHEFN Uncharacterized oxidoreductase Sf... | 169 | 0.02 | 38.9 | 28 | 43 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 23 | Q58505 | 218 | TRKA_METJA Trk system potassium uptake protei... | 68 | 1.1 | 33.1 | 29 | 54 | | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW. | 24 | Q5R7T2 | 553 | GLYR1_PONAB Putative oxidoreductase GLYR1 OS=... | 165 | 1.2 | 33.5 | 23 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 25 | Q562D5 | 534 | GLYR1_XENTR Putative oxidoreductase GLYR1 OS=... | 165 | 1.3 | 33.5 | 24 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 26 | P97014 | 379 | DHPH_SPOUR Phenylalanine dehydrogenase OS=Spo... | 88 | 5.2 | 31.6 | 28 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050175; F:phenylalanine dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 27 | P40332 | 342 | YISS_BACSU Uncharacterized oxidoreductase Yis... | 82 | 5.8 | 31.2 | 26 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q175F8 | 559 | GLYR1_AEDAE Putative oxidoreductase GLYR1 hom... | 167 | 8.9 | 30.8 | 22 | 43 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. |
