rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | O33116 | 528 | SERA_MYCLE D-3-phosphoglycerate dehydrogenase... | 134 | 0.000000000004 | 69.7 | 35 | 51 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 92 | O32264 | 325 | TKRA_BACSU Probable 2-ketogluconate reductase... | 123 | 0.000000000004 | 68.9 | 33 | 52 | | | | | | | | | | | GO:0008873; F:gluconate 2-dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW. | 93 | P0A544 | 528 | SERA_MYCTU D-3-phosphoglycerate dehydrogenase... | 134 | 0.000000000007 | 68.9 | 34 | 51 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0006564; P:L-serine biosynthetic process; IDA:MTBBASE.::GO:0051289; P:protein homotetramerization; IPI:MTBBASE. | 94 | P0A545 | 528 | SERA_MYCBO D-3-phosphoglycerate dehydrogenase... | 134 | 0.000000000007 | 68.9 | 34 | 51 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 95 | Q9S7E4 | 384 | FDH_ARATH Formate dehydrogenase, mitochondria... | 96 | 0.000000000009 | 68.2 | 34 | 61 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009579; C:thylakoid; IDA:TAIR. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR. | 96 | Q5HLU4 | 317 | Y1888_STAEQ Putative 2-hydroxyacid dehydrogen... | 140 | 0.00000000001 | 67.4 | 29 | 48 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 97 | Q99RW8 | 317 | Y2305_STAAM Putative 2-hydroxyacid dehydrogen... | 114 | 0.00000000001 | 67.4 | 33 | 52 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 98 | Q7A417 | 317 | Y2098_STAAN Putative 2-hydroxyacid dehydrogen... | 114 | 0.00000000001 | 67.4 | 33 | 52 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 99 | Q49ZM5 | 318 | Y606_STAS1 Putative 2-hydroxyacid dehydrogena... | 113 | 0.00000000001 | 67.4 | 34 | 53 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 100 | Q9YHU0 | 440 | CTBP1_XENLA C-terminal-binding protein 1 OS=X... | 130 | 0.00000000001 | 67.8 | 30 | 52 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 101 | Q9UBQ7 | 328 | GRHPR_HUMAN Glyoxylate reductase/hydroxypyruv... | 143 | 0.00000000001 | 67.4 | 32 | 46 | GO:0005782; C:peroxisomal matrix; TAS:Reactome. | | | | | | | | | | GO:0008465; F:glycerate dehydrogenase activity; IDA:UniProtKB.::GO:0030267; F:glyoxylate reductase (NADP) activity; IDA:UniProtKB.::GO:0016618; F:hydroxypyruvate reductase activity; IDA:UniProtKB.::GO:0051287; F:NAD binding; TAS:UniProtKB. | | | | | | | | | | GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.::GO:0007588; P:excretion; IMP:UniProtKB.::GO:0046487; P:glyoxylate metabolic process; TAS:Reactome. | 102 | O34815 | 344 | YOAD_BACSU Putative 2-hydroxyacid dehydrogena... | 134 | 0.00000000002 | 67.4 | 34 | 54 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 103 | Q9EQH5 | 445 | CTBP2_RAT C-terminal-binding protein 2 OS=Rat... | 131 | 0.00000000002 | 67.4 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 104 | P56546 | 445 | CTBP2_MOUSE C-terminal-binding protein 2 OS=M... | 131 | 0.00000000002 | 67.4 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 105 | P56545 | 445 | CTBP2_HUMAN C-terminal-binding protein 2 OS=H... | 131 | 0.00000000002 | 67.4 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 106 | Q0VCQ1 | 445 | CTBP2_BOVIN C-terminal-binding protein 2 OS=B... | 131 | 0.00000000002 | 67.4 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 107 | P0CF35 | 236 | FDH2_YEAST Putative formate dehydrogenase 2 O... | 89 | 0.00000000002 | 65.5 | 36 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 108 | P26297 | 333 | LDHD_LACDA D-lactate dehydrogenase OS=20081).... | 145 | 0.00000000002 | 66.6 | 28 | 49 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 109 | Q47748 | 323 | VANH_ENTFA D-specific alpha-keto acid dehydro... | 135 | 0.00000000004 | 66.2 | 30 | 49 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 110 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 131 | 0.00000000004 | 66.6 | 30 | 51 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 111 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 131 | 0.00000000004 | 66.6 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 112 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 131 | 0.00000000004 | 66.2 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 113 | Q03134 | 365 | FDH_EMENI Probable formate dehydrogenase OS=1... | 116 | 0.00000000004 | 66.2 | 38 | 57 | | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 114 | Q8CNB8 | 317 | Y1879_STAES Putative 2-hydroxyacid dehydrogen... | 140 | 0.00000000005 | 65.9 | 28 | 47 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 115 | O94574 | 340 | YGDH_SCHPO Putative 2-hydroxyacid dehydrogena... | 134 | 0.00000000005 | 65.9 | 28 | 51 | GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; ISS:PomBase. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; ISS:PomBase.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0009436; P:glyoxylate catabolic process; ISS:PomBase.::GO:0006111; P:regulation of gluconeogenesis; IC:PomBase. | 116 | P0A9T3 | 410 | SERA_SHIFL D-3-phosphoglycerate dehydrogenase... | 114 | 0.00000000009 | 65.5 | 34 | 56 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 117 | P0A9T0 | 410 | SERA_ECOLI D-3-phosphoglycerate dehydrogenase... | 114 | 0.00000000009 | 65.5 | 34 | 56 | | | | | | | | | | | GO:0047545; F:2-hydroxyglutarate dehydrogenase activity; IDA:EcoCyc.::GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:EcoCyc. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IMP:EcoCyc. | 118 | P0A9T1 | 410 | SERA_ECOL6 D-3-phosphoglycerate dehydrogenase... | 114 | 0.00000000009 | 65.5 | 34 | 56 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 119 | P0A9T2 | 410 | SERA_ECO57 D-3-phosphoglycerate dehydrogenase... | 114 | 0.00000000009 | 65.5 | 34 | 56 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 120 | C8ZHD6 | 376 | FDH2_YEAS8 Formate dehydrogenase 2 OS=(Baker'... | 49 | 1.1 | 34.3 | 45 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 121 | A6ZN46 | 376 | FDH2_YEAS7 Formate dehydrogenase 2 OS=Sacchar... | 49 | 1.1 | 34.3 | 45 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | |