rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9SRR0 | 304 | PEX13_ARATH Peroxisomal membrane protein 13 O... | 107 | 0.034 | 39.7 | 37 | 46 | GO:0005778; C:peroxisomal membrane; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IDA:TAIR. | 32 | Q8I1A6 | 366 | SH3G3_DROWI Endophilin-A OS=Drosophila willis... | 65 | 0.036 | 39.7 | 34 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 33 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 171 | 0.037 | 39.7 | 23 | 38 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 34 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 81 | 0.038 | 40 | 28 | 46 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 35 | Q5RC07 | 716 | ES8L2_PONAB Epidermal growth factor receptor ... | 74 | 0.043 | 40 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 36 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 74 | 0.045 | 40 | 32 | 50 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 37 | Q99K30 | 729 | ES8L2_MOUSE Epidermal growth factor receptor ... | 74 | 0.047 | 39.7 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 38 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 91 | 0.05 | 38.9 | 26 | 52 | | | | | | | | | | | | | | | | | | | | | | 39 | O55033 | 380 | NCK2_MOUSE Cytoplasmic protein NCK2 OS=Mus mu... | 65 | 6.3 | 32.7 | 26 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 40 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 144 | 0.066 | 38.9 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 41 | P43603 | 459 | LSB3_YEAST LAS seventeen-binding protein 3 OS... | 46 | 0.067 | 39.3 | 35 | 65 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD. | 42 | A7A261 | 459 | LSB3_YEAS7 LAS seventeen-binding protein 3 OS... | 46 | 0.067 | 39.3 | 35 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 43 | Q13588 | 217 | GRAP_HUMAN GRB2-related adapter protein OS=Ho... | 43 | 0.069 | 38.5 | 40 | 65 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 44 | P29355 | 228 | SEM5_CAEEL Sex muscle abnormal protein 5 OS=C... | 70 | 0.075 | 38.5 | 29 | 54 | | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase. | 45 | Q63768 | 304 | CRK_RAT Adapter molecule crk OS=Rattus norveg... | 171 | 0.077 | 38.5 | 23 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0051270; P:regulation of cellular component movement; TAS:RGD.::GO:0035020; P:regulation of Rac protein signal transduction; IMP:RGD.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 46 | Q4P5J4 | 593 | HSE1_USTMA Class E vacuolar protein-sorting m... | 69 | 0.078 | 38.9 | 33 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 47 | O43639 | 380 | NCK2_HUMAN Cytoplasmic protein NCK2 OS=Homo s... | 65 | 2.7 | 33.9 | 28 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB. | 48 | P46108 | 304 | CRK_HUMAN Adapter molecule crk OS=Homo sapien... | 171 | 0.088 | 38.5 | 23 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. | 49 | O35180 | 347 | SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ... | 75 | 0.1 | 38.5 | 31 | 45 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 50 | O35413 | 1196 | SRBS2_RAT Sorbin and SH3 domain-containing pr... | 90 | 0.11 | 38.9 | 27 | 48 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 51 | Q66II3 | 229 | GRB2_XENTR Growth factor receptor-bound prote... | 74 | 0.11 | 37.7 | 31 | 50 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 52 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 135 | 0.11 | 38.1 | 25 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 53 | Q8T390 | 369 | SH3G3_DROME Endophilin-A OS=Drosophila melano... | 65 | 0.12 | 38.1 | 32 | 51 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:FlyBase. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 54 | Q8I1I3 | 369 | SH3G3_DROER Endophilin-A OS=Drosophila erecta... | 65 | 0.12 | 38.1 | 32 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 55 | Q3UTJ2 | 1180 | SRBS2_MOUSE Sorbin and SH3 domain-containing ... | 90 | 0.13 | 38.5 | 27 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 56 | Q62421 | 347 | SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo... | 69 | 0.13 | 38.1 | 30 | 46 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 57 | P42680 | 631 | TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo... | 96 | 0.15 | 38.1 | 26 | 45 | GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0010543; P:regulation of platelet activation; IDA:UniProtKB. | 58 | O13736 | 1420 | SLA1_SCHPO Actin cytoskeleton-regulatory comp... | 65 | 0.16 | 38.1 | 35 | 52 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; ISS:PomBase. | 59 | O94875 | 1100 | SRBS2_HUMAN Sorbin and SH3 domain-containing ... | 90 | 0.16 | 38.1 | 27 | 47 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 60 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 74 | 0.17 | 38.1 | 27 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 61 | Q8AXU9 | 353 | SH3G3_CHICK Endophilin-A3 OS=Gallus gallus (C... | 69 | 0.19 | 37.7 | 29 | 45 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |