rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q55CS8 | 695 | MPL2_DICDI MAP kinase phosphatase with leucin... | 68 | 0.14 | 39.7 | 37 | 57 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 92 | P0C598 | 217 | DUPD1_ANOCA Dual specificity phosphatase DUPD... | 69 | 0.14 | 38.5 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 93 | D1J722 | 661 | FTSH_ECTSI ATP-dependent zinc metalloprotease... | 65 | 0.16 | 39.3 | 28 | 52 | GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 94 | Q9UNI6 | 340 | DUS12_HUMAN Dual specificity protein phosphat... | 61 | 0.17 | 38.9 | 36 | 49 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0033133; P:positive regulation of glucokinase activity; IBA:RefGenome. | 95 | P0C5A2 | 211 | DUPD1_CALMI Dual specificity phosphatase DUPD... | 66 | 0.18 | 38.1 | 41 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 96 | Q54Y32 | 856 | MPL3_DICDI MAP kinase phosphatase with leucin... | 52 | 0.19 | 39.3 | 42 | 60 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 97 | Q1LWL2 | 208 | DS22A_DANRE Dual specificity protein phosphat... | 65 | 0.21 | 38.1 | 35 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 98 | Q9D7X3 | 185 | DUS3_MOUSE Dual specificity protein phosphata... | 47 | 0.25 | 37.4 | 43 | 66 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; IBA:RefGenome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0050868; P:negative regulation of T cell activation; IBA:RefGenome.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IBA:RefGenome.::GO:0045931; P:positive regulation of mitotic cell cycle; IBA:RefGenome. | 99 | Q66GT5 | 193 | PTPM1_MOUSE Protein-tyrosine phosphatase mito... | 66 | 0.26 | 37.4 | 35 | 53 | | | | | | | | | | | | | | | | | | | | | | 100 | P0C5A0 | 206 | DUPD1_GASAC Dual specificity phosphatase DUPD... | 66 | 0.28 | 37.7 | 38 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 101 | Q4RQD3 | 211 | DUPD1_TETNG Dual specificity phosphatase DUPD... | 65 | 0.31 | 37.4 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 102 | Q54T76 | 394 | DUSP4_DICDI Probable dual specificity protein... | 110 | 0.32 | 38.1 | 30 | 47 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 103 | Q9QYJ7 | 198 | DUS13_MOUSE Dual specificity protein phosphat... | 64 | 0.32 | 37.4 | 38 | 58 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | | 104 | P0C089 | 193 | PTPM1_RAT Protein-tyrosine phosphatase mitoch... | 66 | 0.32 | 37.4 | 35 | 53 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IBA:RefGenome. | 105 | P97924 | 2959 | KALRN_RAT Kalirin OS=Rattus norvegicus (Rat).... | 230 | 0.43 | 38.1 | 24 | 36 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007409; P:axonogenesis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:HGNC.::GO:0050773; P:regulation of dendrite development; IDA:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 106 | Q5R6H6 | 211 | DUS26_PONAB Dual specificity protein phosphat... | 27 | 0.46 | 37 | 56 | 78 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 107 | Q9BV47 | 211 | DUS26_HUMAN Dual specificity protein phosphat... | 27 | 0.48 | 37 | 56 | 78 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 108 | Q39491 | 276 | PTP3_CHLMO Dual specificity protein phosphata... | 44 | 0.49 | 37.4 | 41 | 57 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 109 | P0C5A1 | 203 | DUPD1_ORYLA Dual specificity phosphatase DUPD... | 46 | 0.51 | 36.6 | 50 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 110 | Q5FVI9 | 211 | DUS26_RAT Dual specificity protein phosphatas... | 27 | 0.53 | 36.6 | 56 | 78 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 111 | Q5RD73 | 185 | DUS3_PONAB Dual specificity protein phosphata... | 50 | 0.59 | 36.2 | 40 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 112 | P51452 | 185 | DUS3_HUMAN Dual specificity protein phosphata... | 50 | 0.59 | 36.2 | 40 | 54 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 113 | A2CG49 | 2964 | KALRN_MOUSE Kalirin OS=Mus musculus (Mouse). ... | 108 | 0.67 | 37.7 | 30 | 40 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 114 | Q9D700 | 211 | DUS26_MOUSE Dual specificity protein phosphat... | 27 | 0.83 | 36.2 | 56 | 78 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; ISS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 115 | Q9UII6 | 198 | DUS13_HUMAN Dual specificity protein phosphat... | 63 | 0.9 | 35.8 | 37 | 54 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0007126; P:meiosis; TAS:ProtInc.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 116 | Q54R42 | 230 | DUSP2_DICDI Probable dual specificity protein... | 64 | 0.9 | 36.2 | 30 | 56 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 117 | Q6CL17 | 603 | VPS27_KLULA Vacuolar protein sorting-associat... | 94 | 1.2 | 36.6 | 27 | 35 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 118 | Q8WUK0 | 201 | PTPM1_HUMAN Protein-tyrosine phosphatase mito... | 66 | 1.2 | 35.4 | 32 | 55 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IBA:RefGenome. | 119 | Q55E39 | 212 | DUSP1_DICDI Probable dual specificity protein... | 100 | 1.4 | 35.4 | 26 | 45 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 120 | O60229 | 2985 | KALRN_HUMAN Kalirin OS=Homo sapiens (Human). ... | 226 | 2 | 35.8 | 23 | 35 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; ISS:HGNC.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc. | 121 | Q17QJ3 | 211 | DUS26_BOVIN Dual specificity protein phosphat... | 27 | 2.1 | 35 | 52 | 78 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | |