rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O14346 | 208 | HACD_SCHPO Probable 3-hydroxyacyl-CoA dehydra... | 196 | 5e-38 | 137 | 45 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase. | 2 | Q5ZEJ0 | 221 | PAS2B_ORYSJ 3-hydroxyacyl-CoA dehydratase PAS... | 206 | 2e-30 | 117 | 40 | 54 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 3 | Q7XSZ4 | 221 | PAS2A_ORYSJ 3-hydroxyacyl-CoA dehydratase PAS... | 206 | 2e-30 | 117 | 39 | 54 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 4 | Q8VZB2 | 221 | PAS2_ARATH 3-hydroxyacyl-CoA dehydratase PAST... | 213 | 4e-30 | 116 | 37 | 54 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0009923; C:fatty acid elongase complex; IPI:TAIR.::GO:0016021; C:integral to membrane; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0080023; F:3R-hydroxyacyl-CoA dehydratase activity; IGI:TAIR. | | | | | | | | | | GO:0030154; P:cell differentiation; IMP:TAIR.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048640; P:negative regulation of developmental growth; IMP:TAIR.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:TAIR.::GO:0051302; P:regulation of cell division; IMP:TAIR.::GO:0042761; P:very long-chain fatty acid biosynthetic process; IMP:TAIR. | 5 | P40857 | 217 | PHS1_YEAST 3-hydroxyacyl-CoA dehydratase PHS1... | 206 | 4e-23 | 97.8 | 36 | 52 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD. | | | | | | | | | | GO:0004300; F:enoyl-CoA hydratase activity; IDA:SGD. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0030148; P:sphingolipid biosynthetic process; IMP:SGD.::GO:0007034; P:vacuolar transport; IMP:SGD. | 6 | Q9D3B1 | 254 | HACD2_MOUSE 3-hydroxyacyl-CoA dehydratase 2 O... | 228 | 6e-21 | 92 | 33 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 7 | Q2KIP8 | 254 | HACD2_BOVIN 3-hydroxyacyl-CoA dehydratase 2 O... | 226 | 2e-20 | 90.5 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 8 | Q6Y1H2 | 254 | HACD2_HUMAN 3-hydroxyacyl-CoA dehydratase 2 O... | 227 | 4e-20 | 90.1 | 32 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 9 | Q5RBK3 | 255 | HACD2_PONAB 3-hydroxyacyl-CoA dehydratase 2 O... | 227 | 4e-20 | 90.1 | 32 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 10 | Q4W1W1 | 249 | HACD1_CANFA 3-hydroxyacyl-CoA dehydratase 1 O... | 224 | 7e-20 | 89 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 11 | B0YJ81 | 288 | HACD1_HUMAN 3-hydroxyacyl-CoA dehydratase 1 O... | 224 | 3e-19 | 87.8 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0007165; P:signal transduction; NAS:ProtInc. | 12 | Q9QY80 | 281 | HACD1_MOUSE 3-hydroxyacyl-CoA dehydratase 1 O... | 225 | 1e-18 | 85.9 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 13 | Q9N1R5 | 288 | HACD1_SHEEP 3-hydroxyacyl-CoA dehydratase 1 O... | 166 | 7e-18 | 83.6 | 33 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 14 | Q5ZM57 | 362 | HACD_CHICK 3-hydroxyacyl-CoA dehydratase OS=G... | 228 | 0.000000000000002 | 77.4 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 15 | Q6GNB5 | 218 | HACD_XENLA 3-hydroxyacyl-CoA dehydratase OS=X... | 167 | 0.000000000007 | 65.5 | 27 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 16 | A2AKM2 | 232 | HACD4_MOUSE 3-hydroxyacyl-CoA dehydratase 4 O... | 165 | 0.0000000001 | 62 | 24 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 17 | Q8K2C9 | 362 | HACD3_MOUSE 3-hydroxyacyl-CoA dehydratase 3 O... | 229 | 0.0000000005 | 61.6 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IDA:MGI.::GO:0007254; P:JNK cascade; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 18 | Q7SY06 | 359 | HADC_DANRE 3-hydroxyacyl-CoA dehydratase OS=D... | 160 | 0.0000000008 | 61.2 | 25 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 19 | A7YY55 | 362 | HACD3_BOVIN 3-hydroxyacyl-CoA dehydratase 3 O... | 156 | 0.000000001 | 60.5 | 24 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 20 | Q5VWC8 | 232 | HACD4_HUMAN 3-hydroxyacyl-CoA dehydratase 4 O... | 165 | 0.000000002 | 59.3 | 24 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 21 | Q5NVQ2 | 364 | PTAD1_PONAB 3-hydroxyacyl-CoA dehydratase 3 O... | 159 | 0.000000002 | 59.7 | 24 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 22 | Q9P035 | 362 | HACD3_HUMAN 3-hydroxyacyl-CoA dehydratase 3 O... | 159 | 0.00000001 | 57.8 | 23 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:ProtInc.::GO:0016601; P:Rac protein signal transduction; NAS:UniProtKB. | 23 | Q0P5C7 | 231 | HACD4_BOVIN 3-hydroxyacyl-CoA dehydratase 4 O... | 164 | 0.0000005 | 52.4 | 23 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 24 | Q54YG8 | 1117 | RLIB_DICDI Protein rliB OS=Dictyostelium disc... | 47 | 0.67 | 34.7 | 38 | 51 | GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | | | | | | | | | | | | 25 | B3Q8B1 | 279 | PDRP_RHOPT Putative pyruvate, phosphate dikin... | 88 | 3.6 | 32 | 32 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q6ND11 | 279 | PDRP_RHOPA Putative pyruvate, phosphate dikin... | 88 | 3.6 | 32 | 32 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | Q1QRY4 | 280 | PDRP_NITHX Putative pyruvate, phosphate dikin... | 84 | 4.2 | 32 | 32 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q3ZXD7 | 357 | MNMA_DEHSC tRNA-specific 2-thiouridylase MnmA... | 40 | 6.2 | 31.6 | 48 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 29 | A5FR85 | 357 | MNMA_DEHSB tRNA-specific 2-thiouridylase MnmA... | 40 | 6.2 | 31.6 | 48 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 30 | Q3Z8D8 | 357 | MNMA_DEHE1 tRNA-specific 2-thiouridylase MnmA... | 40 | 7.6 | 31.2 | 48 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. |