| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q98SW2 | 766 | HIF1A_ONCMY Hypoxia-inducible factor 1-alpha ... | 120 | 0.00008 | 47 | 23 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q9YIB9 | 811 | HIF1A_CHICK Hypoxia-inducible factor 1-alpha ... | 173 | 0.00008 | 47 | 20 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q0PGG7 | 823 | HIF1A_BOSMU Hypoxia-inducible factor 1-alpha ... | 109 | 0.0003 | 45.4 | 21 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q61221 | 836 | HIF1A_MOUSE Hypoxia-inducible factor 1-alpha ... | 109 | 0.0003 | 45.4 | 21 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009434; C:microtubule-based flagellum; IDA:MGI. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0001922; P:B-1 B cell homeostasis; IMP:MGI.::GO:0003208; P:cardiac ventricle morphogenesis; IMP:MGI.::GO:0051216; P:cartilage development; IMP:MGI.::GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0032963; P:collagen metabolic process; IMP:BHF-UCL.::GO:0002248; P:connective tissue replacement involved in inflammatory response wound healing; IMP:BHF-UCL.::GO:0048546; P:digestive tract morphogenesis; IMP:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0051541; P:elastin metabolic process; IMP:BHF-UCL.::GO:0035162; P:embryonic hemopoiesis; IMP:MGI.::GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0061030; P:epithelial cell differentiation involved in mammary gland alveolus development; IMP:MGI.::GO:0001837; P:epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0001947; P:heart looping; IMP:MGI.::GO:0042541; P:hemoglobin biosynthetic process; IMP:MGI.::GO:0060574; P:intestinal epithelial cell maturation; IMP:MGI.::GO:0006089; P:lactate metabolic process; IMP:MGI.::GO:0007595; P:lactation; IMP:MGI.::GO:0046716; P:muscle cell homeostasis; IMP:MGI.::GO:0030502; P:negative regulation of bone mineralization; IMP:MGI.::GO:0045926; P:negative regulation of growth; IMP:MGI.::GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:MGI.::GO:0001755; P:neural crest cell migration; IMP:MGI.::GO:0021502; P:neural fold elevation formation; IMP:MGI.::GO:0003151; P:outflow tract morphogenesis; IMP:MGI.::GO:0032364; P:oxygen homeostasis; IMP:MGI.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:BHF-UCL.::GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:MGI.::GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IGI:MGI.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IMP:MGI.::GO:0050790; P:regulation of catalytic activity; IMP:MGI.::GO:0006110; P:regulation of glycolysis; IGI:MGI.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:MGI.::GO:0014850; P:response to muscle activity; IMP:MGI.::GO:0061298; P:retina vasculature development in camera-type eye; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 5 | O35800 | 825 | HIF1A_RAT Hypoxia-inducible factor 1-alpha OS... | 109 | 0.0004 | 45.1 | 21 | 48 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; TAS:RGD.::GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0060135; P:maternal process involved in female pregnancy; IEP:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:RGD.::GO:0045906; P:negative regulation of vasoconstriction; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q16665 | 826 | HIF1A_HUMAN Hypoxia-inducible factor 1-alpha ... | 109 | 0.0004 | 45.1 | 21 | 48 | GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005667; C:transcription factor complex; IPI:MGI. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.::GO:0032963; P:collagen metabolic process; ISS:BHF-UCL.::GO:0002248; P:connective tissue replacement involved in inflammatory response wound healing; ISS:BHF-UCL.::GO:0051541; P:elastin metabolic process; ISS:BHF-UCL.::GO:0001837; P:epithelial to mesenchymal transition; ISS:BHF-UCL.::GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IC:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0032364; P:oxygen homeostasis; IDA:HGNC.::GO:0045766; P:positive regulation of angiogenesis; IC:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; TAS:BHF-UCL.::GO:0070101; P:positive regulation of chemokine-mediated signaling pathway; IC:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IC:BHF-UCL.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:BHF-UCL.::GO:0045648; P:positive regulation of erythrocyte differentiation; IC:BHF-UCL.::GO:0045821; P:positive regulation of glycolysis; IC:BHF-UCL.::GO:0046886; P:positive regulation of hormone biosynthetic process; IDA:BHF-UCL.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; TAS:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IC:BHF-UCL.::GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:BHF-UCL.::GO:0032909; P:regulation of transforming growth factor beta2 production; IMP:BHF-UCL.::GO:0010573; P:vascular endothelial growth factor production; IDA:BHF-UCL. | 7 | Q309Z6 | 819 | HIF1A_EOSBA Hypoxia-inducible factor 1-alpha ... | 109 | 0.0004 | 45.1 | 21 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q9XTA5 | 823 | HIF1A_BOVIN Hypoxia-inducible factor 1-alpha ... | 109 | 0.0004 | 45.1 | 21 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q9Y2N7 | 669 | HIF3A_HUMAN Hypoxia-inducible factor 3-alpha ... | 88 | 0.001 | 43.9 | 31 | 52 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 10 | P97481 | 874 | EPAS1_MOUSE Endothelial PAS domain-containing... | 90 | 0.001 | 43.5 | 22 | 52 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:MGI. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0048625; P:myoblast cell fate commitment; IMP:BHF-UCL.::GO:0042415; P:norepinephrine metabolic process; IMP:MGI.::GO:0002027; P:regulation of heart rate; IMP:MGI.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:MGI.::GO:0001666; P:response to hypoxia; IMP:MGI.::GO:0043129; P:surfactant homeostasis; IMP:MGI.::GO:0007601; P:visual perception; IMP:MGI. | 11 | P05709 | 697 | SIM_DROME Protein single-minded OS=Drosophila... | 80 | 0.001 | 43.1 | 26 | 49 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; IPI:FlyBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:FlyBase.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007420; P:brain development; IMP:FlyBase.::GO:0035225; P:determination of genital disc primordium; IMP:FlyBase.::GO:0007398; P:ectoderm development; TAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0007419; P:ventral cord development; IMP:FlyBase.::GO:0007418; P:ventral midline development; IMP:UniProtKB. | 12 | Q99814 | 870 | EPAS1_HUMAN Endothelial PAS domain-containing... | 90 | 0.001 | 43.1 | 22 | 51 | GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0048625; P:myoblast cell fate commitment; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0001666; P:response to hypoxia; IDA:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 13 | Q9JHS2 | 662 | HIF3A_RAT Hypoxia-inducible factor 3-alpha OS... | 88 | 0.002 | 43.1 | 31 | 52 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0001666; P:response to hypoxia; TAS:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q0VBL6 | 662 | HIF3A_MOUSE Hypoxia-inducible factor 3-alpha ... | 88 | 0.002 | 43.1 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IPI:MGI.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001666; P:response to hypoxia; IDA:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IPI:MGI. | 15 | O15945 | 642 | ARNT_DROME Aryl hydrocarbon receptor nuclear ... | 32 | 0.95 | 34.3 | 34 | 66 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; IPI:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:FlyBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IMP:FlyBase.::GO:0071456; P:cellular response to hypoxia; IDA:FlyBase.::GO:0032869; P:cellular response to insulin stimulus; IDA:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0007425; P:epithelial cell fate determination, open tracheal system; NAS:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; TAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q14190 | 667 | SIM2_HUMAN Single-minded homolog 2 OS=Homo sa... | 80 | 0.003 | 42 | 26 | 51 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q61324 | 712 | ARNT2_MOUSE Aryl hydrocarbon receptor nuclear... | 77 | 0.004 | 42 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0017162; F:aryl hydrocarbon receptor binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IEP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0001666; P:response to hypoxia; TAS:UniProtKB.::GO:0009636; P:response to toxin; TAS:UniProtKB.::GO:0009410; P:response to xenobiotic stimulus; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q78E60 | 712 | ARNT2_RAT Aryl hydrocarbon receptor nuclear t... | 77 | 0.004 | 42 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q9HBZ2 | 717 | ARNT2_HUMAN Aryl hydrocarbon receptor nuclear... | 77 | 0.004 | 42 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0017162; F:aryl hydrocarbon receptor binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q9DG12 | 737 | ARNT2_DANRE Aryl hydrocarbon receptor nuclear... | 73 | 7.4 | 31.6 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q98SJ5 | 745 | SIM1A_DANRE Single-minded homolog 1-A OS=Dani... | 49 | 4.4 | 32.3 | 33 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0071542; P:dopaminergic neuron differentiation; IMP:ZFIN.::GO:0021979; P:hypothalamus cell differentiation; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q9JHS1 | 874 | EPAS1_RAT Endothelial PAS domain-containing p... | 43 | 0.007 | 41.2 | 33 | 72 | GO:0005737; C:cytoplasm; IDA:RGD. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | O70361 | 1113 | PER3_MOUSE Period circadian protein homolog 3... | 57 | 0.007 | 41.2 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007623; P:circadian rhythm; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q61045 | 765 | SIM1_MOUSE Single-minded homolog 1 OS=Mus mus... | 80 | 0.008 | 40.8 | 26 | 49 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001657; P:ureteric bud development; IEP:UniProtKB. | 25 | Q9EPW1 | 626 | BMAL1_RAT Aryl hydrocarbon receptor nuclear t... | 69 | 0.1 | 37.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0042752; P:regulation of circadian rhythm; NAS:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | O88529 | 626 | BMAL1_MESAU Aryl hydrocarbon receptor nuclear... | 69 | 0.099 | 37.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q91YA9 | 626 | BMAL1_NANGA Aryl hydrocarbon receptor nuclear... | 69 | 0.1 | 37.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | O00327 | 626 | BMAL1_HUMAN Aryl hydrocarbon receptor nuclear... | 69 | 0.1 | 37.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IPI:MGI. | | | | | | | | | | GO:0017162; F:aryl hydrocarbon receptor binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IGI:MGI.::GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007623; P:circadian rhythm; TAS:ProtInc.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL. | 29 | A0MLS5 | 626 | BMAL1_HORSE Aryl hydrocarbon receptor nuclear... | 69 | 0.1 | 37.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q8CJE2 | 1119 | PER3_RAT Period circadian protein homolog 3 O... | 57 | 0.008 | 40.8 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | Q6YGZ5 | 633 | BMAL1_TYTAL Aryl hydrocarbon receptor nuclear... | 69 | 0.1 | 37.4 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
