rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q7M4T0 | 480 | NEG1_NEUCR Endo-1,6-beta-D-glucanase OS=1257 ... | 481 | 2e-154 | 455 | 48 | 66 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:InterPro. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0046557; F:glucan endo-1,6-beta-glucosidase activity; IEA:EC.::GO:0004348; F:glucosylceramidase activity; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro. | 2 | Q8J0I9 | 490 | GUN16_TRIHA Endo-1,6-beta-D-glucanase BGN16.3... | 505 | 6e-133 | 400 | 42 | 62 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:InterPro. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0046557; F:glucan endo-1,6-beta-glucosidase activity; IEA:EC.::GO:0004348; F:glucosylceramidase activity; IEA:InterPro. | | | | | | | | | | GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0005976; P:polysaccharide metabolic process; IDA:UniProtKB.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro. | 3 | P17439 | 515 | GLCM_MOUSE Glucosylceramidase OS=Mus musculus... | 425 | 8e-23 | 104 | 27 | 44 | GO:0043202; C:lysosomal lumen; IDA:BHF-UCL.::GO:0005765; C:lysosomal membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:EC.::GO:0005102; F:receptor binding; IPI:BHF-UCL. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0007040; P:lysosome organization; IEA:InterPro. | 4 | Q70KH2 | 536 | GLCM_PIG Glucosylceramidase OS=Sus scrofa (Pi... | 407 | 2e-21 | 100 | 27 | 43 | GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW. | 5 | Q2KHZ8 | 536 | GLCM_BOVIN Glucosylceramidase OS=Bos taurus (... | 405 | 7e-21 | 99.4 | 27 | 42 | GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW. | 6 | Q9BDT0 | 536 | GLCM_PANTR Glucosylceramidase OS=Pan troglody... | 418 | 1e-20 | 98.6 | 26 | 43 | GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW. | 7 | P04062 | 536 | GLCM_HUMAN Glucosylceramidase OS=Homo sapiens... | 418 | 1e-20 | 98.2 | 26 | 43 | GO:0043202; C:lysosomal lumen; ISS:BHF-UCL.::GO:0005765; C:lysosomal membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IDA:BHF-UCL.::GO:0005102; F:receptor binding; ISS:BHF-UCL. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.::GO:0046513; P:ceramide biosynthetic process; IMP:BHF-UCL.::GO:0006680; P:glucosylceramide catabolic process; IMP:BHF-UCL.::GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.::GO:0032715; P:negative regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.::GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.::GO:0046512; P:sphingosine biosynthetic process; IMP:BHF-UCL.::GO:0023021; P:termination of signal transduction; IMP:BHF-UCL. | 8 | Q5R8E3 | 536 | GLCM_PONAB Glucosylceramidase OS=Pongo abelii... | 418 | 4e-20 | 96.7 | 26 | 43 | GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0007040; P:lysosome organization; IEA:InterPro. | 9 | P54803 | 685 | GALC_HUMAN Galactocerebrosidase OS=Homo sapie... | 178 | 0.029 | 40.8 | 22 | 40 | GO:0043202; C:lysosomal lumen; TAS:Reactome. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 10 | O02791 | 685 | GALC_MACMU Galactocerebrosidase OS=Macaca mul... | 178 | 0.031 | 40.4 | 22 | 40 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 11 | Q45070 | 422 | XYNC_BACSU Glucuronoxylanase xynC OS=Bacillus... | 63 | 0.032 | 40.4 | 35 | 51 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:InterPro. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:InterPro.::GO:0033940; F:glucuronoarabinoxylan endo-1,4-beta-xylanase activity; IEA:EC. | | | | | | | | | | GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.::GO:0045493; P:xylan catabolic process; IEA:UniProtKB-KW. | 12 | P54818 | 684 | GALC_MOUSE Galactocerebrosidase OS=Mus muscul... | 176 | 0.048 | 40 | 22 | 39 | GO:0005764; C:lysosome; TAS:MGI.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IMP:MGI. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 13 | Q0VA39 | 678 | GALC_XENTR Galactocerebrosidase OS=Xenopus tr... | 142 | 0.094 | 38.9 | 25 | 42 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 14 | Q498K0 | 677 | GALC_XENLA Galactocerebrosidase OS=Xenopus la... | 182 | 0.11 | 38.9 | 20 | 37 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 15 | B5X3C1 | 666 | GALC_SALSA Galactocerebrosidase OS=Salmo sala... | 168 | 0.14 | 38.5 | 23 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 16 | Q6YK37 | 423 | XYNC_BACIU Glucuronoxylanase xynC OS=Bacillus... | 68 | 0.47 | 36.6 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:InterPro. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004348; F:glucosylceramidase activity; IEA:InterPro.::GO:0033940; F:glucuronoarabinoxylan endo-1,4-beta-xylanase activity; IEA:EC. | | | | | | | | | | GO:0007040; P:lysosome organization; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.::GO:0045493; P:xylan catabolic process; IEA:UniProtKB-KW. | 17 | P54804 | 669 | GALC_CANFA Galactocerebrosidase OS=Canis fami... | 139 | 0.84 | 35.8 | 22 | 44 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 18 | Q5SNX7 | 660 | GALC_DANRE Galactocerebrosidase OS=Danio reri... | 138 | 2.4 | 34.7 | 25 | 45 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043169; F:cation binding; IEA:InterPro.::GO:0004336; F:galactosylceramidase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro. | 19 | A9B1D4 | 255 | SURE_HERA2 5'-nucleotidase surE OS=Herpetosip... | 107 | 7.2 | 32.3 | 29 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008253; F:5'-nucleotidase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | |