| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q4L7U1 | 346 | LEU3_STAHJ 3-isopropylmalate dehydrogenase OS... | 92 | 0.000000000002 | 65.9 | 43 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 242 | Q3IJS3 | 358 | LEU3_PSEHT 3-isopropylmalate dehydrogenase OS... | 64 | 0.000000000002 | 65.9 | 55 | 69 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 243 | Q55BI2 | 354 | IDHA_DICDI Isocitrate dehydrogenase [NAD] reg... | 92 | 0.000000000003 | 65.5 | 45 | 61 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 244 | Q44471 | 364 | TTUC1_AGRVI Probable tartrate dehydrogenase/d... | 104 | 0.000000000003 | 65.5 | 42 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050319; F:tartrate decarboxylase activity; IEA:EC.::GO:0009027; F:tartrate dehydrogenase activity; IEA:EC. | | | | | | | | | | | 245 | Q9D6R2 | 366 | IDH3A_MOUSE Isocitrate dehydrogenase [NAD] su... | 106 | 0.000000000005 | 65.1 | 42 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 246 | Q28480 | 347 | IDH3A_MACFA Isocitrate dehydrogenase [NAD] su... | 106 | 0.000000000005 | 64.7 | 42 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 247 | Q5R678 | 366 | IDH3A_PONAB Isocitrate dehydrogenase [NAD] su... | 106 | 0.000000000006 | 64.7 | 42 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 248 | P50213 | 366 | IDH3A_HUMAN Isocitrate dehydrogenase [NAD] su... | 106 | 0.000000000007 | 64.3 | 42 | 56 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 249 | Q945K7 | 374 | IDH5_ARATH Isocitrate dehydrogenase [NAD] cat... | 82 | 0.000000000009 | 64.3 | 46 | 61 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:TAIR.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 250 | P41563 | 366 | IDH3A_BOVIN Isocitrate dehydrogenase [NAD] su... | 106 | 0.00000000001 | 63.9 | 42 | 56 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 251 | Q5HS77 | 358 | LEU3_CAMJR 3-isopropylmalate dehydrogenase OS... | 90 | 0.00000000001 | 63.9 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 252 | P76251 | 361 | DMLA_ECOLI D-malate dehydrogenase [decarboxyl... | 108 | 0.00000000001 | 63.9 | 40 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006108; P:malate metabolic process; IDA:UniProtKB. | 253 | C4LJH3 | 342 | LEU3_CORK4 3-isopropylmalate dehydrogenase OS... | 86 | 0.00000000001 | 63.5 | 48 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 254 | Q9PLW0 | 358 | LEU3_CAMJE 3-isopropylmalate dehydrogenase OS... | 90 | 0.00000000001 | 63.5 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 255 | O14104 | 362 | LYS12_SCHPO Probable homoisocitrate dehydroge... | 84 | 0.00000000001 | 63.5 | 46 | 62 | GO:0005739; C:mitochondrion; ISS:PomBase. | | | | | | | | | | GO:0047046; F:homoisocitrate dehydrogenase activity; ISS:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0009085; P:lysine biosynthetic process; IMP:PomBase. | 256 | O27441 | 329 | LEU3_METTH 3-isopropylmalate dehydrogenase OS... | 101 | 0.00000000001 | 63.5 | 44 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 257 | Q5HMF8 | 347 | LEU3_STAEQ 3-isopropylmalate dehydrogenase OS... | 76 | 0.00000000001 | 63.5 | 43 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 258 | Q93714 | 358 | IDH3A_CAEEL Probable isocitrate dehydrogenase... | 103 | 0.00000000001 | 63.5 | 40 | 54 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 259 | Q71Y34 | 350 | LEU3_LISMF 3-isopropylmalate dehydrogenase OS... | 105 | 0.00000000002 | 63.2 | 43 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 260 | P50180 | 313 | LEU3_NEILA 3-isopropylmalate dehydrogenase OS... | 59 | 0.00000000002 | 62.8 | 58 | 71 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 261 | P28241 | 369 | IDH2_YEAST Isocitrate dehydrogenase [NAD] sub... | 100 | 0.00000000002 | 63.2 | 43 | 55 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD. | 262 | Q99NA5 | 366 | IDH3A_RAT Isocitrate dehydrogenase [NAD] subu... | 86 | 0.00000000002 | 63.2 | 43 | 59 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 263 | Q3AYS1 | 357 | LEU3_SYNS9 3-isopropylmalate dehydrogenase OS... | 85 | 0.00000000002 | 62.8 | 47 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 264 | P94631 | 340 | LEU3_CORGL 3-isopropylmalate dehydrogenase OS... | 87 | 0.00000000003 | 62.4 | 46 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 265 | A4QDP9 | 340 | LEU3_CORGB 3-isopropylmalate dehydrogenase OS... | 87 | 0.00000000003 | 62.4 | 46 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 266 | Q7V1R9 | 357 | LEU3_PROMP 3-isopropylmalate dehydrogenase OS... | 102 | 0.00000000004 | 62 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 267 | Q92A27 | 350 | LEU3_LISIN 3-isopropylmalate dehydrogenase OS... | 105 | 0.00000000005 | 62 | 43 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 268 | Q8CNL2 | 347 | LEU3_STAES 3-isopropylmalate dehydrogenase OS... | 76 | 0.00000000005 | 62 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 269 | Q5WPZ9 | 367 | LEU3_BUCCC 3-isopropylmalate dehydrogenase OS... | 105 | 0.00000000006 | 62 | 37 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 270 | P40495 | 371 | LYS12_YEAST Homoisocitrate dehydrogenase, mit... | 85 | 0.00000000006 | 61.6 | 51 | 61 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0047046; F:homoisocitrate dehydrogenase activity; IDA:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 271 | P59028 | 352 | LEU3_CHLTE 3-isopropylmalate dehydrogenase OS... | 106 | 0.00000000007 | 61.6 | 41 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. |
