| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P19835 | 753 | CEL_HUMAN Bile salt-activated lipase OS=Homo ... | 104 | 0.001 | 44.3 | 43 | 51 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome. | | | | | | | | | | GO:0047372; F:acylglycerol lipase activity; TAS:Reactome.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0008201; F:heparin binding; NAS:UniProtKB.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004771; F:sterol esterase activity; NAS:UniProtKB.::GO:0004806; F:triglyceride lipase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0009062; P:fatty acid catabolic process; NAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; NAS:UniProtKB.::GO:0044258; P:intestinal lipid catabolic process; NAS:UniProtKB.::GO:0030157; P:pancreatic juice secretion; IDA:UniProtKB.::GO:0018350; P:protein esterification; NAS:UniProtKB.::GO:0006641; P:triglyceride metabolic process; IC:UniProtKB. | 2 | Q9VDW3 | 1669 | DMDB_DROME Dystrophin, isoform B OS=Drosophil... | 125 | 0.001 | 44.7 | 28 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 3 | A2AL36 | 2334 | CNTRL_MOUSE Centriolin OS=Mus musculus (Mouse... | 132 | 0.002 | 43.5 | 29 | 36 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 4 | O75962 | 3097 | TRIO_HUMAN Triple functional domain protein O... | 95 | 0.55 | 35.8 | 29 | 39 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 5 | Q95Q95 | 2697 | TOR_CAEEL Target of rapamycin homolog OS=Caen... | 99 | 0.04 | 39.7 | 26 | 39 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0000492; P:box C/D snoRNP assembly; IMP:WormBase.::GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006629; P:lipid metabolic process; IMP:WormBase.::GO:0045727; P:positive regulation of translation; IMP:WormBase.::GO:0009408; P:response to heat; IMP:WormBase.::GO:0031929; P:TOR signaling cascade; IMP:WormBase.::GO:0006412; P:translation; IMP:WormBase. | 6 | Q9NTJ3 | 1288 | SMC4_HUMAN Structural maintenance of chromoso... | 30 | 5 | 32.7 | 40 | 50 | GO:0000796; C:condensin complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro. | 7 | Q3TKT4 | 1613 | SMCA4_MOUSE Transcription activator BRG1 OS=M... | 123 | 0.1 | 38.1 | 26 | 36 | GO:0000792; C:heterochromatin; IDA:MGI.::GO:0071565; C:nBAF complex; IDA:UniProtKB.::GO:0071564; C:npBAF complex; IDA:UniProtKB.::GO:0005719; C:nuclear euchromatin; IDA:MGI.::GO:0005726; C:perichromatin fibrils; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.::GO:0016514; C:SWI/SNF complex; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0035887; P:aortic smooth muscle cell differentiation; IMP:MGI.::GO:0001832; P:blastocyst growth; IMP:MGI.::GO:0001835; P:blastocyst hatching; IMP:MGI.::GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0006338; P:chromatin remodeling; IMP:MGI.::GO:0060318; P:definitive erythrocyte differentiation; IMP:MGI.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:MGI.::GO:0035116; P:embryonic hindlimb morphogenesis; IMP:MGI.::GO:0048562; P:embryonic organ morphogenesis; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007403; P:glial cell fate determination; IMP:MGI.::GO:0060347; P:heart trabecula formation; IGI:MGI.::GO:0030902; P:hindbrain development; IMP:MGI.::GO:0043966; P:histone H3 acetylation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0006346; P:methylation-dependent chromatin silencing; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006334; P:nucleosome assembly; TAS:MGI.::GO:0043388; P:positive regulation of DNA binding; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0019827; P:stem cell maintenance; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001570; P:vasculogenesis; IMP:MGI. | 8 | Q16U49 | 1578 | MED14_AEDAE Mediator of RNA polymerase II tra... | 170 | 5.2 | 32.7 | 22 | 34 | GO:0016592; C:mediator complex; IEA:InterPro. | | | | | | | | | | GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro. | | | | | | | | | | | 9 | Q7Z7A1 | 2325 | CNTRL_HUMAN Centriolin OS=Homo sapiens (Human... | 133 | 0.13 | 37.7 | 26 | 35 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome. | 10 | Q8K1P7 | 1613 | SMCA4_RAT Transcription activator BRG1 OS=Rat... | 123 | 0.15 | 37.7 | 26 | 36 | GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0016514; C:SWI/SNF complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0043044; P:ATP-dependent chromatin remodeling; IDA:RGD.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006337; P:nucleosome disassembly; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q2EG98 | 2201 | PK1L3_MOUSE Polycystic kidney disease protein... | 116 | 3.2 | 33.5 | 23 | 28 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006812; P:cation transport; IDA:BHF-UCL.::GO:0071468; P:cellular response to acidity; IDA:BHF-UCL.::GO:0001581; P:detection of chemical stimulus involved in sensory perception of sour taste; IDA:BHF-UCL.::GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. | 12 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 110 | 0.57 | 35.8 | 31 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 13 | Q58HI1 | 1012 | PELP1_XENLA Proline-, glutamic acid- and leuc... | 53 | 0.77 | 35.4 | 42 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | P28023 | 1280 | DCTN1_RAT Dynactin subunit 1 OS=Rattus norveg... | 45 | 0.82 | 35.4 | 40 | 56 | GO:0005868; C:cytoplasmic dynein complex; IDA:RGD.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008017; F:microtubule binding; NAS:RGD.::GO:0003777; F:microtubule motor activity; TAS:RGD. | | | | | | | | | | GO:0007017; P:microtubule-based process; TAS:RGD.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 15 | O60610 | 1272 | DIAP1_HUMAN Protein diaphanous homolog 1 OS=H... | 96 | 0.94 | 35 | 42 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0072686; C:mitotic spindle; IDA:BHF-UCL.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0005102; F:receptor binding; NAS:ProtInc.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0071420; P:cellular response to histamine; IMP:BHF-UCL.::GO:0035372; P:protein localization to microtubule; IMP:BHF-UCL.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:BHF-UCL.::GO:0007605; P:sensory perception of sound; TAS:ProtInc. | 16 | O08788 | 1281 | DCTN1_MOUSE Dynactin subunit 1 OS=Mus musculu... | 45 | 1.2 | 34.7 | 40 | 56 | GO:0031252; C:cell leading edge; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 17 | P16960 | 5035 | RYR1_PIG Ryanodine receptor 1 OS=Sus scrofa (... | 104 | 1.6 | 34.7 | 32 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 18 | E9PTG8 | 967 | STK10_RAT Serine/threonine-protein kinase 10 ... | 60 | 1.7 | 34.3 | 33 | 42 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 19 | Q14202 | 1370 | ZMYM3_HUMAN Zinc finger MYM-type protein 3 OS... | 172 | 3.3 | 33.5 | 23 | 33 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 20 | P34339 | 1076 | EIF3A_CAEEL Eukaryotic translation initiation... | 122 | 1.8 | 34.3 | 27 | 34 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 21 | Q03387 | 788 | IF41_WHEAT Eukaryotic initiation factor iso-4... | 96 | 2.7 | 33.5 | 33 | 44 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 22 | P23470 | 1445 | PTPRG_HUMAN Receptor-type tyrosine-protein ph... | 163 | 3.2 | 33.5 | 25 | 34 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 23 | O15357 | 1258 | SHIP2_HUMAN Phosphatidylinositol 3,4,5-trisph... | 65 | 3.3 | 33.5 | 31 | 38 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:UniProtKB.::GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 24 | Q9JLM4 | 1370 | ZMYM3_MOUSE Zinc finger MYM-type protein 3 OS... | 202 | 4.2 | 33.1 | 23 | 33 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 25 | Q9C093 | 1822 | SPEF2_HUMAN Sperm flagellar protein 2 OS=Homo... | 87 | 6.1 | 32.7 | 28 | 34 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0019205; F:nucleobase-containing compound kinase activity; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro. |
