rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | Q9HB55 | 503 | CP343_HUMAN Cytochrome P450 3A43 OS=Homo sapi... | 100 | 0.76 | 33.5 | 28 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 332 | P79153 | 520 | CP11A_CAPHI Cholesterol side-chain cleavage e... | 103 | 0.78 | 33.5 | 23 | 39 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 333 | Q9UVC3 | 512 | CP51_CUNEL Lanosterol 14-alpha demethylase OS... | 84 | 0.79 | 33.5 | 23 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 334 | Q92045 | 514 | CP11A_DASAM Cholesterol side-chain cleavage e... | 98 | 0.85 | 33.5 | 22 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 335 | Q59990 | 444 | CP120_SYNY3 Putative cytochrome P450 120 OS=S... | 78 | 0.87 | 33.1 | 27 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 336 | P11511 | 503 | CP19A_HUMAN Cytochrome P450 19A1 OS=Homo sapi... | 37 | 0.9 | 33.1 | 35 | 57 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 337 | O70537 | 501 | CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice... | 107 | 1.1 | 33.1 | 25 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 338 | Q9VE01 | 536 | C12A5_DROME Probable cytochrome P450 12a5, mi... | 93 | 1.1 | 33.1 | 25 | 45 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 339 | P50859 | 533 | CP51_CANGA Lanosterol 14-alpha demethylase OS... | 133 | 1.1 | 33.1 | 25 | 38 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 340 | P17666 | 490 | CP2CE_RABIT Cytochrome P450 2C14 OS=Oryctolag... | 54 | 1.2 | 33.1 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 341 | P11712 | 490 | CP2C9_HUMAN Cytochrome P450 2C9 OS=Homo sapie... | 54 | 1.2 | 32.7 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0052741; F:(R)-limonene 6-monooxygenase activity; IEA:EC.::GO:0018675; F:(S)-limonene 6-monooxygenase activity; IEA:EC.::GO:0018676; F:(S)-limonene 7-monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IMP:BHF-UCL. | | | | | | | | | | GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0032787; P:monocarboxylic acid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0019627; P:urea metabolic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 342 | Q9VGB4 | 493 | CP132_DROME Probable cytochrome P450 313a2 OS... | 98 | 1.2 | 32.7 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 343 | P00182 | 489 | CP2C3_RABIT Cytochrome P450 2C3 OS=Oryctolagu... | 54 | 1.2 | 32.7 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 344 | P33264 | 490 | CP2CR_MESAU Cytochrome P450 2C27 OS=Mesocrice... | 70 | 1.3 | 32.7 | 29 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 345 | P37120 | 513 | C75A2_SOLME Flavonoid 3',5'-hydroxylase OS=So... | 107 | 1.3 | 32.7 | 28 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 346 | P15123 | 487 | CP2CG_RABIT Cytochrome P450 2C16 OS=Oryctolag... | 54 | 1.3 | 32.7 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 347 | P00181 | 490 | CP2C2_RABIT Cytochrome P450 2C2 OS=Oryctolagu... | 49 | 1.4 | 32.7 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 348 | P13527 | 509 | CP6A1_MUSDO Cytochrome P450 6A1 OS=Musca dome... | 97 | 1.4 | 32.7 | 26 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 349 | P79430 | 503 | CP192_PIG Cytochrome P450 19 type II OS=Sus s... | 40 | 1.5 | 32.7 | 33 | 55 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 350 | Q29624 | 503 | CP191_PIG Cytochrome P450 19 type I OS=Sus sc... | 40 | 1.5 | 32.7 | 33 | 55 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 351 | Q01361 | 500 | CP2DE_BOVIN Cytochrome P450 2D14 OS=Bos tauru... | 49 | 1.5 | 32.7 | 29 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 352 | Q9VYQ7 | 483 | CP311_DROME Probable cytochrome P450 311a1 OS... | 98 | 1.5 | 32.7 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 353 | P0A512 | 451 | CP51_MYCTU Lanosterol 14-alpha demethylase OS... | 53 | 1.6 | 32.3 | 26 | 45 | GO:0005829; C:cytosol; IDA:MTBBASE. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:MTBBASE.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0008398; F:sterol 14-demethylase activity; IDA:MTBBASE. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 354 | P0A513 | 451 | CP51_MYCBO Lanosterol 14-alpha demethylase OS... | 53 | 1.6 | 32.3 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 355 | P51589 | 502 | CP2J2_HUMAN Cytochrome P450 2J2 OS=Homo sapie... | 43 | 1.6 | 32.7 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0008405; F:arachidonic acid 11,12-epoxygenase activity; IDA:BHF-UCL.::GO:0008404; F:arachidonic acid 14,15-epoxygenase activity; IDA:BHF-UCL.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0071614; F:linoleic acid epoxygenase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:BHF-UCL.::GO:0043651; P:linoleic acid metabolic process; IDA:BHF-UCL.::GO:0008016; P:regulation of heart contraction; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL. | 356 | P79202 | 520 | CP11A_SHEEP Cholesterol side-chain cleavage e... | 103 | 1.6 | 32.3 | 23 | 39 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 357 | P29980 | 459 | CPXN_NOSS1 Probable cytochrome P450 110 OS=No... | 36 | 1.6 | 32.3 | 36 | 58 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW. | 358 | P11371 | 487 | CP2C4_RABIT Cytochrome P450 2C4 OS=Oryctolagu... | 54 | 1.8 | 32.3 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 359 | P00179 | 487 | CP2C5_RABIT Cytochrome P450 2C5 OS=Oryctolagu... | 54 | 1.8 | 32.3 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 360 | P14263 | 528 | CP51_CANTR Lanosterol 14-alpha demethylase OS... | 87 | 1.9 | 32.3 | 28 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 361 | O46658 | 500 | CP2DP_PIG Vitamin D(3) 25-hydroxylase OS=Sus ... | 49 | 1.9 | 32.3 | 29 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | |