rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P39956 | 796 | RPH1_YEAST DNA damage-responsive transcriptio... | 123 | 1e-21 | 105 | 39 | 60 | GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:SGD.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 2 | Q5RD88 | 1064 | KDM4A_PONAB Lysine-specific demethylase 4A OS... | 104 | 0.000000003 | 65.5 | 33 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | O75164 | 1064 | KDM4A_HUMAN Lysine-specific demethylase 4A OS... | 104 | 0.000000003 | 65.9 | 33 | 61 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q8BW72 | 1064 | KDM4A_MOUSE Lysine-specific demethylase 4A OS... | 104 | 0.000000002 | 66.2 | 33 | 61 | | | | | | | | | | | GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q9H3R0 | 1056 | KDM4C_HUMAN Lysine-specific demethylase 4C OS... | 104 | 0.000000006 | 64.7 | 32 | 61 | GO:0000790; C:nuclear chromatin; IDA:BHF-UCL. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q8VCD7 | 1054 | KDM4C_MOUSE Lysine-specific demethylase 4C OS... | 104 | 0.000000002 | 65.9 | 33 | 62 | | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q3U2K5 | 510 | KDM4D_MOUSE Lysine-specific demethylase 4D OS... | 100 | 0.0000005 | 57.8 | 27 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q6B0I6 | 523 | KDM4D_HUMAN Lysine-specific demethylase 4D OS... | 100 | 0.000005 | 54.7 | 28 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | A1A5Q5 | 510 | KDM4D_RAT Lysine-specific demethylase 4D OS=R... | 100 | 0.0000002 | 58.9 | 28 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q91VY5 | 1086 | KDM4B_MOUSE Lysine-specific demethylase 4B OS... | 104 | 0.00000000009 | 70.9 | 36 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q9V6L0 | 590 | KDM4B_DROME Probable lysine-specific demethyl... | 100 | 0.000001 | 56.6 | 31 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | O94953 | 1096 | KDM4B_HUMAN Lysine-specific demethylase 4B OS... | 104 | 0.0000000004 | 68.6 | 34 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | B2RXH2 | 506 | KDM4E_HUMAN Lysine-specific demethylase 4E OS... | 106 | 0.0000002 | 59.3 | 30 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q9V333 | 495 | KDM4A_DROME Probable lysine-specific demethyl... | 101 | 0.004 | 45.1 | 33 | 55 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IMP:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q9U297 | 922 | KDM4_CAEEL Lysine-specific demethylase 4 OS=C... | 107 | 0.0006 | 48.1 | 25 | 53 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IMP:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q03833 | 894 | GIS1_YEAST Transcriptional activator/represso... | 108 | 0.0000000000003 | 78.6 | 36 | 60 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IMP:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IC:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001300; P:chronological cell aging; IMP:SGD.::GO:0060275; P:maintenance of stationary phase in response to starvation; IMP:SGD.::GO:0071071; P:regulation of phospholipid biosynthetic process; IMP:SGD. | 17 | Q9VMJ7 | 1838 | KDM5_DROME Lysine-specific demethylase lid OS... | 39 | 0.2 | 40 | 41 | 62 | GO:0070822; C:Sin3-type complex; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0043992; F:histone acetyltransferase activity (H3-K9 specific); IMP:FlyBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IMP:FlyBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q23541 | 1477 | KDM5_CAEEL Lysine-specific demethylase rbr-2 ... | 236 | 7e-29 | 130 | 35 | 50 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:WormBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:WormBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q3UXZ9 | 1690 | KDM5A_MOUSE Lysine-specific demethylase 5A OS... | 54 | 0.042 | 42.4 | 39 | 57 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q8GUI6 | 954 | JMJ14_ARATH Probable lysine-specific demethyl... | 84 | 3.1 | 36.2 | 27 | 40 | GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:TAIR.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010216; P:maintenance of DNA methylation; IMP:TAIR.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0048573; P:photoperiodism, flowering; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | A1YVX4 | 1516 | KDM5C_PIG Lysine-specific demethylase 5C OS=S... | 74 | 0.0002 | 50.1 | 35 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | P29375 | 1690 | KDM5A_HUMAN Lysine-specific demethylase 5A OS... | 40 | 0.21 | 40 | 40 | 63 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 23 | P41229 | 1560 | KDM5C_HUMAN Lysine-specific demethylase 5C OS... | 40 | 0.003 | 46.2 | 50 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | P41230 | 1554 | KDM5C_MOUSE Lysine-specific demethylase 5C OS... | 40 | 0.003 | 45.8 | 50 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | Q38JA7 | 1556 | KDM5C_CANFA Lysine-specific demethylase 5C OS... | 40 | 0.003 | 45.8 | 50 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | Q30DN6 | 1545 | KDM5D_CANFA Lysine-specific demethylase 5D OS... | 40 | 0.004 | 45.4 | 50 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 27 | Q5XUN4 | 1535 | KDM5D_PANTR Lysine-specific demethylase 5D OS... | 40 | 0.013 | 43.9 | 48 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 28 | Q9BY66 | 1539 | KDM5D_HUMAN Lysine-specific demethylase 5D OS... | 40 | 0.013 | 43.9 | 48 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007283; P:spermatogenesis; NAS:UniProtKB. | 29 | Q61T02 | 1482 | KDM5_CAEBR Lysine-specific demethylase rbr-2 ... | 39 | 2.3 | 36.6 | 38 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q80Y84 | 1544 | KDM5B_MOUSE Lysine-specific demethylase 5B OS... | 40 | 2.8 | 36.2 | 38 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | Q9UGL1 | 1544 | KDM5B_HUMAN Lysine-specific demethylase 5B OS... | 40 | 2.9 | 36.2 | 38 | 60 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:GDB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |