| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q4FZD7 | 595 | PLK5_MOUSE Inactive serine/threonine-protein ... | 243 | 1.3 | 34.7 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0002357; P:defense response to tumor cell; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006927; P:transformed cell apoptotic process; IMP:UniProtKB. | 62 | Q5Z9J0 | 580 | MPK12_ORYSJ Mitogen-activated protein kinase ... | 28 | 1.3 | 34.7 | 50 | 71 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW. | 63 | O74304 | 1436 | WIN1_SCHPO MAP kinase kinase kinase win1 OS=S... | 205 | 1.4 | 34.7 | 27 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase. | 64 | Q9GM70 | 397 | ST17A_RABIT Serine/threonine-protein kinase 1... | 43 | 1.4 | 34.3 | 40 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; ISS:UniProtKB. | 65 | P53350 | 603 | PLK1_HUMAN Serine/threonine-protein kinase PL... | 232 | 1.4 | 34.3 | 22 | 37 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000942; C:condensed nuclear chromosome outer kinetochore; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0051233; C:spindle midzone; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:BHF-UCL. | | | | | | | | | | GO:0010997; F:anaphase-promoting complex binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0051297; P:centrosome organization; IMP:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.::GO:0007091; P:mitotic metaphase/anaphase transition; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0000088; P:mitotic prophase; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.::GO:0031648; P:protein destabilization; IDA:UniProtKB.::GO:0071168; P:protein localization to chromatin; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0090007; P:regulation of mitotic anaphase; IMP:BHF-UCL.::GO:0043393; P:regulation of protein binding; IMP:BHF-UCL. | 66 | Q5GLH2 | 343 | TRIB2_BOVIN Tribbles homolog 2 OS=Bos taurus ... | 36 | 1.4 | 34.3 | 36 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB. | 67 | P70032 | 598 | PLK1_XENLA Serine/threonine-protein kinase PL... | 45 | 1.4 | 34.3 | 36 | 56 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB. | 68 | Q5R669 | 343 | TRIB2_PONAB Tribbles homolog 2 OS=Pongo abeli... | 36 | 1.4 | 34.3 | 36 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB. | 69 | Q28283 | 343 | TRIB2_CANFA Tribbles homolog 2 OS=Canis famil... | 36 | 1.4 | 34.3 | 36 | 58 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB. | 70 | Q8K4K3 | 343 | TRIB2_MOUSE Tribbles homolog 2 OS=Mus musculu... | 36 | 1.5 | 33.9 | 36 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IDA:BHF-UCL.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.::GO:0055106; F:ubiquitin-protein ligase regulator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0045599; P:negative regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IC:BHF-UCL.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB. | 71 | Q92519 | 343 | TRIB2_HUMAN Tribbles homolog 2 OS=Homo sapien... | 36 | 1.5 | 33.9 | 36 | 58 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.::GO:0055106; F:ubiquitin-protein ligase regulator activity; ISS:BHF-UCL. | | | | | | | | | | GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.::GO:0045081; P:negative regulation of interleukin-10 biosynthetic process; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; NAS:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB. | 72 | Q8BWD8 | 501 | CDK19_MOUSE Cyclin-dependent kinase 19 OS=Mus... | 51 | 1.5 | 34.3 | 35 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 73 | Q8JH47 | 464 | CDK8_DANRE Cyclin-dependent kinase 8 OS=Danio... | 254 | 1.6 | 34.3 | 24 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 74 | Q9C5C0 | 615 | MPK18_ARATH Mitogen-activated protein kinase ... | 28 | 1.6 | 34.3 | 54 | 64 | GO:0005737; C:cytoplasm; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:TAIR. | 75 | Q9BWU1 | 502 | CDK19_HUMAN Cyclin-dependent kinase 19 OS=Hom... | 51 | 1.6 | 34.3 | 35 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 76 | Q9P7I2 | 335 | KCC1_SCHPO Calcium/calmodulin-dependent prote... | 43 | 1.7 | 33.9 | 40 | 53 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0019722; P:calcium-mediated signaling; IC:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 77 | Q8LST2 | 557 | WNK7_ARATH Probable serine/threonine-protein ... | 194 | 1.7 | 34.3 | 22 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 78 | Q6RET6 | 527 | CCAMK_PEA Calcium and calcium/calmodulin-depe... | 37 | 2 | 33.9 | 41 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0009877; P:nodulation; IEA:UniProtKB-KW. | 79 | Q0D847 | 601 | WNK3_ORYSJ Probable serine/threonine-protein ... | 117 | 2.2 | 33.9 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 80 | Q2TA25 | 602 | PLK1_BOVIN Serine/threonine-protein kinase PL... | 232 | 2.4 | 33.5 | 22 | 37 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB. | 81 | Q1KTF2 | 357 | HOG1_MYCGM Mitogen-activated protein kinase H... | 242 | 2.5 | 33.5 | 25 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 82 | Q66I46 | 466 | MKNK2_XENTR MAP kinase-interacting serine/thr... | 59 | 2.5 | 33.5 | 31 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 83 | Q58D94 | 420 | MKNK1_BOVIN MAP kinase-interacting serine/thr... | 59 | 2.6 | 33.5 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 84 | Q15772 | 3267 | SPEG_HUMAN Striated muscle preferentially exp... | 31 | 2.7 | 33.5 | 48 | 68 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 85 | Q80X41 | 440 | VRK1_MOUSE Serine/threonine-protein kinase VR... | 66 | 3 | 33.1 | 27 | 48 | GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:MGI. | 86 | Q9BUB5 | 465 | MKNK1_HUMAN MAP kinase-interacting serine/thr... | 59 | 3.2 | 33.1 | 31 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 87 | Q4G050 | 413 | MKNK1_RAT MAP kinase-interacting serine/threo... | 59 | 3.3 | 33.1 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 88 | Q9YHZ5 | 310 | PIM2_DANRE Serine/threonine-protein kinase pi... | 36 | 3.4 | 32.7 | 36 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; NAS:ZFIN. | 89 | Q6EU49 | 612 | WNK4_ORYSJ Probable serine/threonine-protein ... | 140 | 4.1 | 32.7 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | O08605 | 427 | MKNK1_MOUSE MAP kinase-interacting serine/thr... | 59 | 4.2 | 32.7 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; NAS:UniProtKB. | 91 | P84390 | 382 | US03_EHV1V Serine/threonine-protein kinase US... | 248 | 4.8 | 32.3 | 25 | 39 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. |
