rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | F7DKV7 | 309 | SIR5_XENTR NAD-dependent protein deacylase si... | 80 | 0.00000000000002 | 72 | 43 | 63 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 32 | Q9YB13 | 245 | NPD_AERPE NAD-dependent protein deacylase OS=... | 70 | 0.00000000000002 | 71.2 | 50 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | Q5HZN8 | 309 | SIR5A_XENLA NAD-dependent protein deacylase s... | 80 | 0.00000000000002 | 72 | 43 | 63 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 34 | Q8ZT00 | 249 | NPD2_PYRAE NAD-dependent protein deacylase 2 ... | 54 | 0.00000000000002 | 71.2 | 56 | 74 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 35 | E1BRE2 | 309 | SIR5_CHICK NAD-dependent protein deacylase si... | 80 | 0.00000000000003 | 72 | 43 | 64 | | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 36 | Q9NXA8 | 310 | SIR5_HUMAN NAD-dependent protein deacylase si... | 75 | 0.00000000000003 | 71.6 | 45 | 63 | GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; IDA:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.::GO:0006476; P:protein deacetylation; IDA:UniProtKB. | 37 | Q8K2C6 | 310 | SIR5_MOUSE NAD-dependent protein deacylase si... | 82 | 0.00000000000004 | 71.2 | 43 | 60 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 38 | F7EZ75 | 310 | SIR5_MACMU NAD-dependent protein deacylase si... | 75 | 0.00000000000004 | 71.2 | 45 | 63 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 39 | Q9CM50 | 234 | NPD_PASMU NAD-dependent protein deacylase OS=... | 63 | 0.00000000000004 | 70.5 | 51 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 40 | Q7UFQ9 | 239 | NPD_RHOBA NAD-dependent protein deacylase OS=... | 64 | 0.00000000000009 | 69.7 | 52 | 66 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 41 | Q584D5 | 244 | SIR5_TRYB2 NAD-dependent protein deacetylase ... | 65 | 0.00000000000009 | 69.7 | 51 | 65 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 42 | Q4Q2Y6 | 243 | SIR5_LEIMA NAD-dependent protein deacetylase ... | 58 | 0.0000000000003 | 68.2 | 53 | 67 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 43 | Q5SIH7 | 254 | NPD_THET8 NAD-dependent protein deacylase OS=... | 73 | 0.0000000000004 | 67.8 | 45 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 44 | Q72IV5 | 254 | NPD_THET2 NAD-dependent protein deacylase OS=... | 73 | 0.0000000000009 | 67 | 44 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 45 | Q669P6 | 243 | NPD_YERPS NAD-dependent protein deacylase OS=... | 54 | 0.000000000002 | 65.9 | 54 | 70 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 46 | Q8ZFR1 | 243 | NPD_YERPE NAD-dependent protein deacylase OS=... | 54 | 0.000000000002 | 65.9 | 54 | 70 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 47 | Q68FX9 | 310 | SIR5_RAT NAD-dependent protein deacylase sirt... | 75 | 0.000000000002 | 66.6 | 43 | 60 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 48 | Q8R9N6 | 242 | NPD1_THETN NAD-dependent protein deacylase 1 ... | 53 | 0.000000000003 | 65.1 | 53 | 72 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 49 | Q607X6 | 255 | NPD_METCA NAD-dependent protein deacylase OS=... | 77 | 0.000000000003 | 65.1 | 44 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 50 | Q68F47 | 309 | SIR5B_XENLA NAD-dependent protein deacylase s... | 80 | 0.000000000009 | 64.7 | 39 | 59 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 51 | Q8A3H9 | 234 | NPD_BACTN NAD-dependent protein deacylase OS=... | 61 | 0.00000000003 | 62.4 | 46 | 66 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 52 | Q9A2S6 | 238 | NPD_CAUCR NAD-dependent protein deacylase OS=... | 55 | 0.00000000007 | 61.2 | 53 | 69 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 53 | Q8EFN2 | 243 | NPD_SHEON NAD-dependent protein deacylase OS=... | 54 | 0.0000000001 | 60.8 | 52 | 67 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 54 | Q88BY5 | 262 | NPD_PSEPK NAD-dependent protein deacylase OS=... | 122 | 0.0000000002 | 60.5 | 33 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 55 | Q9ZJW8 | 234 | NPD_HELPJ NAD-dependent protein deacylase OS=... | 68 | 0.0000000005 | 58.9 | 43 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 56 | Q9ZAB8 | 208 | NPD_AGGAC NAD-dependent protein deacylase OS=... | 53 | 0.000000002 | 56.6 | 47 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 57 | O25849 | 229 | NPD_HELPY NAD-dependent protein deacylase OS=... | 68 | 0.000000005 | 56.2 | 41 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 58 | Q8Y015 | 246 | NPD_RALSO NAD-dependent protein deacylase OS=... | 68 | 0.00000005 | 53.5 | 44 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 59 | Q9JN05 | 233 | NPD_CAMJE NAD-dependent protein deacylase OS=... | 62 | 0.00000005 | 53.5 | 42 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 60 | Q5HU51 | 233 | NPD_CAMJR NAD-dependent protein deacylase OS=... | 62 | 0.00000007 | 53.1 | 42 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 61 | Q9RYD4 | 246 | NPD_DEIRA NAD-dependent protein deacylase OS=... | 59 | 0.0000001 | 52.4 | 44 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |