| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q8K348 | 493 | ACV1C_MOUSE Activin receptor type-1C OS=Mus m... | 288 | 0.0002 | 46.6 | 25 | 40 | GO:0048179; C:activin receptor complex; ISS:UniProtKB. | | | | | | | | | | GO:0016361; F:activin receptor activity, type I; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0019915; P:lipid storage; IMP:MGI.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0002021; P:response to dietary excess; IMP:MGI.::GO:0009749; P:response to glucose stimulus; IMP:MGI.::GO:0032868; P:response to insulin stimulus; IMP:MGI. | 2 | P70539 | 493 | ACV1C_RAT Activin receptor type-1C OS=Rattus ... | 288 | 0.0003 | 46.2 | 25 | 40 | GO:0048179; C:activin receptor complex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD. | | | | | | | | | | GO:0048185; F:activin binding; IDA:MGI.::GO:0016361; F:activin receptor activity, type I; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:HGNC.::GO:0070700; F:BMP receptor binding; IDA:RGD.::GO:0046872; F:metal ion binding; IC:UniProtKB.::GO:0046332; F:SMAD binding; IDA:HGNC.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0021549; P:cerebellum development; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0030901; P:midbrain development; IEP:RGD.::GO:0001541; P:ovarian follicle development; IEP:RGD.::GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0007181; P:transforming growth factor beta receptor complex assembly; IDA:RGD. | 3 | Q8NER5 | 493 | ACV1C_HUMAN Activin receptor type-1C OS=Homo ... | 288 | 0.0007 | 45.1 | 24 | 40 | GO:0048179; C:activin receptor complex; IDA:UniProtKB. | | | | | | | | | | GO:0016361; F:activin receptor activity, type I; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IC:UniProtKB.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB. | 4 | Q91286 | 824 | FGFR2_PLEWA Fibroblast growth factor receptor... | 220 | 0.002 | 43.9 | 24 | 37 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.::GO:0045165; P:cell fate commitment; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0048730; P:epidermis morphogenesis; ISS:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0032808; P:lacrimal gland development; ISS:UniProtKB.::GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0048286; P:lung alveolus development; ISS:UniProtKB.::GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.::GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.::GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.::GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0016331; P:morphogenesis of embryonic epithelium; ISS:UniProtKB.::GO:0035264; P:multicellular organism growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0035265; P:organ growth; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.::GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.::GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB. | 5 | P18461 | 823 | FGFR2_CHICK Fibroblast growth factor receptor... | 291 | 0.003 | 43.1 | 22 | 36 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 6 | P21802 | 821 | FGFR2_HUMAN Fibroblast growth factor receptor... | 291 | 0.004 | 42.7 | 22 | 36 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.::GO:0045165; P:cell fate commitment; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; ISS:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; ISS:UniProtKB.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; ISS:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; ISS:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; ISS:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0032808; P:lacrimal gland development; ISS:UniProtKB.::GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0048286; P:lung alveolus development; ISS:UniProtKB.::GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.::GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.::GO:0060615; P:mammary gland bud formation; ISS:UniProtKB.::GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.::GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0035264; P:multicellular organism growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0035265; P:organ growth; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.::GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0021860; P:pyramidal neuron development; ISS:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.::GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; TAS:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; TAS:UniProtKB.::GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB.::GO:0021847; P:ventricular zone neuroblast division; ISS:UniProtKB. | 7 | Q91287 | 796 | FGFR3_PLEWA Fibroblast growth factor receptor... | 291 | 0.004 | 42.4 | 23 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 8 | Q91147 | 729 | FGFR2_NOTVI Fibroblast growth factor receptor... | 220 | 0.005 | 42.4 | 23 | 37 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 9 | P21803 | 821 | FGFR2_MOUSE Fibroblast growth factor receptor... | 291 | 0.006 | 42 | 22 | 36 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IMP:UniProtKB.::GO:0005576; C:extracellular region; TAS:MGI.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:MGI.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IGI:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0030282; P:bone mineralization; IMP:MGI.::GO:0060349; P:bone morphogenesis; IMP:MGI.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; IMP:MGI.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; IMP:MGI.::GO:0048755; P:branching morphogenesis of a nerve; IMP:MGI.::GO:0060449; P:bud elongation involved in lung branching; IMP:MGI.::GO:0045165; P:cell fate commitment; IDA:MGI.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0009880; P:embryonic pattern specification; IMP:MGI.::GO:0061031; P:endodermal digestive tract morphogenesis; IMP:MGI.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IMP:MGI.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; IMP:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; IMP:MGI.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; IMP:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; IMP:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; IMP:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0032808; P:lacrimal gland development; IMP:MGI.::GO:0060601; P:lateral sprouting from an epithelium; IMP:MGI.::GO:0070307; P:lens fiber cell development; IGI:MGI.::GO:0060174; P:limb bud formation; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0060463; P:lung lobe morphogenesis; IMP:MGI.::GO:0060484; P:lung-associated mesenchyme development; IMP:MGI.::GO:0060615; P:mammary gland bud formation; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; IGI:MGI.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; IMP:MGI.::GO:0030901; P:midbrain development; IGI:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0045839; P:negative regulation of mitosis; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0042476; P:odontogenesis; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0030916; P:otic vesicle formation; IMP:MGI.::GO:0003148; P:outflow tract septum morphogenesis; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051781; P:positive regulation of cell division; IMP:MGI.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IMP:MGI.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IGI:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IMP:MGI.::GO:0060523; P:prostate epithelial cord elongation; IMP:MGI.::GO:0021860; P:pyramidal neuron development; IMP:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IMP:MGI.::GO:0010453; P:regulation of cell fate commitment; IMP:MGI.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IMP:MGI.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0051150; P:regulation of smooth muscle cell differentiation; IMP:MGI.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; IMP:MGI.::GO:0048489; P:synaptic vesicle transport; IMP:MGI.::GO:0001657; P:ureteric bud development; IGI:MGI.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI.::GO:0021847; P:ventricular zone neuroblast division; IMP:UniProtKB. | 10 | P18460 | 806 | FGFR3_CHICK Fibroblast growth factor receptor... | 290 | 0.008 | 41.6 | 23 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 11 | Q03364 | 813 | FGFR2_XENLA Fibroblast growth factor receptor... | 289 | 0.008 | 41.6 | 21 | 36 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 12 | O42127 | 802 | FGFR3_XENLA Fibroblast growth factor receptor... | 118 | 0.012 | 41.2 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 13 | P22607 | 806 | FGFR3_HUMAN Fibroblast growth factor receptor... | 290 | 0.012 | 41.2 | 22 | 36 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070977; P:bone maturation; ISS:BHF-UCL.::GO:0002062; P:chondrocyte differentiation; TAS:UniProtKB.::GO:0035988; P:chondrocyte proliferation; TAS:UniProtKB.::GO:0003416; P:endochondral bone growth; TAS:UniProtKB.::GO:0001958; P:endochondral ossification; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0000165; P:MAPK cascade; TAS:ProtInc.::GO:0048640; P:negative regulation of developmental growth; ISS:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.::GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB. | 14 | Q552C6 | 635 | ZAK2_DICDI Dual specificity protein kinase za... | 204 | 0.016 | 40.8 | 21 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0045860; P:positive regulation of protein kinase activity; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0010468; P:regulation of gene expression; IDA:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 15 | Q8JG38 | 817 | FGFR2_DANRE Fibroblast growth factor receptor... | 291 | 0.016 | 40.8 | 22 | 36 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 16 | Q09147 | 1052 | FGFR2_DROME Fibroblast growth factor receptor... | 297 | 0.019 | 40.4 | 21 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IC:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:FlyBase. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IEP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0035153; P:epithelial cell type specification, open tracheal system; IMP:FlyBase.::GO:0046847; P:filopodium assembly; IMP:FlyBase.::GO:0035215; P:genital disc development; IEP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0030517; P:negative regulation of axon extension; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; NAS:FlyBase.::GO:0007429; P:secondary branching, open tracheal system; IMP:FlyBase.::GO:0007430; P:terminal branching, open tracheal system; IMP:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; IMP:FlyBase. | 17 | Q54RJ4 | 979 | IKSA_DICDI Probable serine/threonine-protein ... | 104 | 0.02 | 40.4 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q8R9T6 | 625 | PKN1_THETN Probable serine/threonine-protein ... | 241 | 0.025 | 40 | 21 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | Q9FMY3 | 341 | STPKL_ARATH Serine/threonine-protein kinase-l... | 189 | 0.032 | 39.3 | 22 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | P34265 | 437 | KIN31_CAEEL Probable tyrosine-protein kinase ... | 100 | 0.037 | 39.3 | 37 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 21 | Q04589 | 822 | FGFR1_RAT Fibroblast growth factor receptor 1... | 291 | 0.041 | 39.3 | 21 | 37 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050839; F:cell adhesion molecule binding; IPI:RGD.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0008201; F:heparin binding; ISS:UniProtKB. | | | | | | | | | | GO:0021954; P:central nervous system neuron development; IMP:RGD.::GO:0021837; P:motogenic signaling involved in postnatal olfactory bulb interneuron migration; IMP:RGD.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:RGD.::GO:0031175; P:neuron projection development; IDA:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:RGD.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IDA:RGD.::GO:0010863; P:positive regulation of phospholipase C activity; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051930; P:regulation of sensory perception of pain; IMP:RGD.::GO:0072091; P:regulation of stem cell proliferation; IMP:RGD.::GO:0019827; P:stem cell maintenance; IMP:RGD. | 22 | Q86PM4 | 816 | FGFR_HYDVU Fibroblast growth factor receptor ... | 113 | 0.044 | 39.3 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 23 | Q61851 | 801 | FGFR3_MOUSE Fibroblast growth factor receptor... | 118 | 0.05 | 39.3 | 27 | 42 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070977; P:bone maturation; IMP:BHF-UCL.::GO:0048640; P:negative regulation of developmental growth; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; ISS:UniProtKB.::GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; ISS:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0035121; P:tail morphogenesis; IMP:BHF-UCL. | 24 | Q5XJV6 | 1424 | LMTK3_MOUSE Serine/threonine-protein kinase L... | 59 | 0.052 | 39.3 | 37 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 25 | Q91285 | 816 | FGFR1_PLEWA Fibroblast growth factor receptor... | 118 | 0.053 | 38.9 | 28 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 26 | Q96Q04 | 1460 | LMTK3_HUMAN Serine/threonine-protein kinase L... | 59 | 0.054 | 39.3 | 37 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 27 | Q552C1 | 1555 | Y9957_DICDI Probable serine/threonine-protein... | 87 | 0.058 | 38.9 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q91743 | 828 | FGFR4_XENLA Fibroblast growth factor receptor... | 118 | 0.074 | 38.5 | 26 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 29 | Q2MHE4 | 390 | HT1_ARATH Serine/threonine-protein kinase HT1... | 242 | 0.076 | 38.1 | 23 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010119; P:regulation of stomatal movement; IMP:TAIR. | 30 | Q75JK0 | 781 | ZAK1_DICDI Dual specificity protein kinase za... | 183 | 0.081 | 38.5 | 21 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.::GO:0001708; P:cell fate specification; IMP:UniProtKB.::GO:0033674; P:positive regulation of kinase activity; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0061118; P:regulation of positive chemotaxis to cAMP; IMP:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 31 | Q90330 | 713 | FGFR4_COTCO Fibroblast growth factor receptor... | 118 | 0.086 | 38.5 | 30 | 42 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. |
