rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P25340 | 473 | ERG4_YEAST Delta(24(24(1)))-sterol reductase ... | 471 | 0 | 729 | 75 | 86 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000246; F:delta24(24-1) sterol reductase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 2 | P36209 | 453 | STS1_SCHPO Delta(24(24(1)))-sterol reductase ... | 442 | 1e-169 | 492 | 54 | 68 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000246; F:delta24(24-1) sterol reductase activity; ISS:PomBase. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0071473; P:cellular response to cation stress; IMP:PomBase.::GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.::GO:0090002; P:establishment of protein localization in plasma membrane; IMP:PomBase.::GO:0071210; P:protein insertion into membrane raft; IMP:PomBase.::GO:0042493; P:response to drug; IMP:PomBase. | 3 | Q54PP1 | 462 | ERG24_DICDI Delta(14)-sterol reductase OS=Dic... | 436 | 7e-60 | 209 | 32 | 49 | GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; ISS:dictyBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IC:dictyBase. | 4 | Q5R7H4 | 615 | LBR_PONAB Lamin-B receptor OS=Pongo abelii (S... | 473 | 9e-60 | 212 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q14739 | 615 | LBR_HUMAN Lamin-B receptor OS=Homo sapiens (H... | 473 | 1e-58 | 209 | 31 | 48 | GO:0005639; C:integral to nuclear inner membrane; TAS:ProtInc. | | | | | | | | | | GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005521; F:lamin binding; TAS:ProtInc.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 6 | O08984 | 620 | LBR_RAT Lamin-B receptor OS=Rattus norvegicus... | 450 | 2e-56 | 202 | 31 | 48 | GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IDA:RGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q3U9G9 | 626 | LBR_MOUSE Lamin-B receptor OS=Mus musculus (M... | 450 | 1e-53 | 195 | 29 | 47 | GO:0005637; C:nuclear inner membrane; TAS:MGI.::GO:0005652; C:nuclear lamina; TAS:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q09195 | 424 | ERG24_SCHPO Delta(14)-sterol reductase OS=Sch... | 452 | 9e-53 | 189 | 31 | 48 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; ISS:PomBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase. | 9 | P23913 | 637 | LBR_CHICK Lamin-B receptor OS=Gallus gallus (... | 467 | 2e-52 | 192 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q71KT5 | 418 | ERG24_MOUSE Delta(14)-sterol reductase OS=Mus... | 453 | 2e-50 | 182 | 30 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 11 | P38670 | 490 | ERG24_NEUCR Delta(14)-sterol reductase OS=125... | 515 | 4e-50 | 183 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 12 | P78575 | 430 | ERG24_ASCIM Delta(14)-sterol reductase OS=Asc... | 452 | 6e-48 | 176 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 13 | O76062 | 418 | ERG24_HUMAN Delta(14)-sterol reductase OS=Hom... | 334 | 7e-47 | 172 | 31 | 49 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 14 | Q8WMV1 | 418 | ERG24_BOVIN Delta(14)-sterol reductase OS=Bos... | 347 | 1e-44 | 166 | 31 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 15 | P32462 | 438 | ERG24_YEAST Delta(14)-sterol reductase OS=Sac... | 467 | 6e-44 | 165 | 28 | 46 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 16 | Q01447 | 485 | ERG24_FUSSO Delta(14)-sterol reductase OS=Fus... | 505 | 8e-42 | 159 | 29 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 17 | Q5UQI4 | 447 | DHCR7_MIMIV Probable 7-dehydrocholesterol red... | 342 | 1e-37 | 147 | 31 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 18 | Q6P4M0 | 473 | DHCR7_XENTR 7-dehydrocholesterol reductase OS... | 481 | 8e-37 | 145 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 19 | Q7ZXH1 | 473 | DHCR7_XENLA 7-dehydrocholesterol reductase OS... | 454 | 1e-36 | 144 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 20 | Q7SXF1 | 478 | DHCR7_DANRE 7-dehydrocholesterol reductase OS... | 309 | 9e-36 | 142 | 30 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 21 | O88455 | 471 | DHCR7_MOUSE 7-dehydrocholesterol reductase OS... | 344 | 1e-34 | 139 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:MGI. | | | | | | | | | | GO:0001568; P:blood vessel development; IMP:MGI.::GO:0030154; P:cell differentiation; IMP:MGI.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0030324; P:lung development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IMP:MGI. | 22 | Q5E9J5 | 475 | DHCR7_BOVIN 7-dehydrocholesterol reductase OS... | 326 | 1e-34 | 139 | 31 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 23 | Q9Z2Z8 | 471 | DHCR7_RAT 7-dehydrocholesterol reductase OS=R... | 327 | 2e-34 | 138 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IMP:RGD. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IDA:RGD.::GO:0045540; P:regulation of cholesterol biosynthetic process; IDA:RGD. | 24 | Q9UBM7 | 475 | DHCR7_HUMAN 7-dehydrocholesterol reductase OS... | 464 | 7e-33 | 133 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005640; C:nuclear outer membrane; IDA:UniProtKB. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IMP:UniProtKB. | 25 | O13597 | 512 | ERG24_SEPLY Delta(14)-sterol reductase OS=Sep... | 367 | 3e-32 | 132 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 26 | Q9LDU6 | 432 | ST7R_ARATH 7-dehydrocholesterol reductase OS=... | 405 | 6e-32 | 130 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0009918; F:sterol delta7 reductase activity; IMP:TAIR. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IMP:TAIR.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 27 | Q9LDR4 | 369 | ERG24_ARATH Delta(14)-sterol reductase OS=Ara... | 388 | 1e-31 | 128 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IMP:TAIR. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 28 | Q8MLV1 | 741 | LBR_DROME Lamin-B receptor OS=Drosophila mela... | 311 | 0.45 | 37 | 21 | 36 | GO:0005639; C:integral to nuclear inner membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005521; F:lamin binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006997; P:nucleus organization; IC:UniProtKB. |