| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P21243 | 252 | PSA6_YEAST Proteasome component C7-alpha OS=S... | 241 | 2e-135 | 388 | 78 | 88 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IC:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD. | 2 | O94517 | 244 | PSA6_SCHPO Probable proteasome subunit alpha ... | 245 | 5e-89 | 270 | 55 | 70 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:PomBase. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase. | 3 | P60901 | 246 | PSA6_RAT Proteasome subunit alpha type-6 OS=R... | 247 | 1e-86 | 264 | 53 | 70 | GO:0016363; C:nuclear matrix; ISS:BHF-UCL.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:BHF-UCL.::GO:0030017; C:sarcomere; IDA:BHF-UCL. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:BHF-UCL.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 4 | P60900 | 246 | PSA6_HUMAN Proteasome subunit alpha type-6 OS... | 247 | 1e-86 | 264 | 53 | 70 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0016363; C:nuclear matrix; ISS:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005844; C:polysome; IDA:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:BHF-UCL.::GO:0030017; C:sarcomere; ISS:BHF-UCL. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; IPI:BHF-UCL.::GO:0035639; F:purine ribonucleoside triphosphate binding; NAS:BHF-UCL.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 5 | Q2YDE4 | 246 | PSA6_BOVIN Proteasome subunit alpha type-6 OS... | 247 | 1e-86 | 264 | 53 | 70 | | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 6 | Q9QUM9 | 246 | PSA6_MOUSE Proteasome subunit alpha type-6 OS... | 247 | 2e-86 | 263 | 53 | 69 | GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:BHF-UCL.::GO:0030017; C:sarcomere; ISS:BHF-UCL. | | | | | | | | | | GO:0003723; F:RNA binding; IDA:BHF-UCL.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0007519; P:skeletal muscle tissue development; NAS:BHF-UCL.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 7 | Q9LSU3 | 246 | PSA6_ORYSJ Proteasome subunit alpha type-6 OS... | 247 | 2e-85 | 261 | 51 | 71 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 8 | Q9XG77 | 246 | PSA6_TOBAC Proteasome subunit alpha type-6 OS... | 247 | 5e-85 | 259 | 51 | 71 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 9 | O81146 | 246 | PSA6A_ARATH Proteasome subunit alpha type-6-A... | 247 | 1e-82 | 254 | 50 | 69 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010043; P:response to zinc ion; IEP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 10 | O48551 | 246 | PSA6_SOYBN Proteasome subunit alpha type-6 OS... | 247 | 4e-82 | 252 | 50 | 70 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 11 | O81147 | 246 | PSA6B_ARATH Proteasome subunit alpha type-6-B... | 247 | 1e-81 | 251 | 49 | 71 | GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 12 | O17586 | 246 | PSA6_CAEEL Proteasome subunit alpha type-6 OS... | 247 | 2e-78 | 243 | 49 | 66 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 13 | Q9XZJ4 | 244 | PSA6_DROME Proteasome subunit alpha type-6 OS... | 247 | 1e-76 | 238 | 48 | 67 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 14 | Q54XM7 | 250 | PSA6_DICDI Proteasome subunit alpha type-6 OS... | 245 | 3e-73 | 230 | 47 | 65 | GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 15 | Q9GU37 | 266 | PSA1_TRYBB Proteasome subunit alpha type-1 OS... | 251 | 5e-49 | 168 | 39 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 16 | Q8TYB7 | 246 | PSA_METKA Proteasome subunit alpha OS=100938)... | 232 | 1e-39 | 143 | 34 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 17 | C6A459 | 260 | PSA_THESM Proteasome subunit alpha OS=Thermoc... | 234 | 8e-36 | 133 | 32 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 18 | O26782 | 248 | PSA_METTH Proteasome subunit alpha OS=thermoa... | 241 | 2e-35 | 132 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 19 | Q8U0L6 | 260 | PSA_PYRFU Proteasome subunit alpha OS=Pyrococ... | 238 | 2e-35 | 132 | 33 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 20 | O59219 | 260 | PSA_PYRHO Proteasome subunit alpha OS=NBRC 10... | 238 | 5e-35 | 131 | 33 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 21 | Q469M6 | 249 | PSA_METBF Proteasome subunit alpha OS=Methano... | 243 | 8e-35 | 130 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 22 | Q8TPX5 | 247 | PSA_METAC Proteasome subunit alpha OS=C2A). G... | 243 | 1e-34 | 130 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 23 | O29760 | 246 | PSA_ARCFU Proteasome subunit alpha OS=9628 / ... | 225 | 1e-34 | 129 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 24 | O59770 | 253 | PSA3_SCHPO Probable proteasome subunit alpha ... | 183 | 2e-34 | 129 | 38 | 57 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:PomBase. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase. | 25 | P25787 | 234 | PSA2_HUMAN Proteasome subunit alpha type-2 OS... | 243 | 2e-34 | 129 | 32 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 26 | Q3T0Y5 | 234 | PSA2_BOVIN Proteasome subunit alpha type-2 OS... | 243 | 2e-34 | 129 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 27 | P49722 | 234 | PSA2_MOUSE Proteasome subunit alpha type-2 OS... | 243 | 3e-34 | 128 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 28 | P17220 | 234 | PSA2_RAT Proteasome subunit alpha type-2 OS=R... | 243 | 3e-34 | 128 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 29 | Q8PTU1 | 249 | PSA_METMA Proteasome subunit alpha OS=JCM 118... | 243 | 4e-34 | 128 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 30 | Q59565 | 247 | PSA_METTE Proteasome subunit alpha OS=Methano... | 225 | 8e-34 | 127 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 31 | Q9V122 | 260 | PSA_PYRAB Proteasome subunit alpha OS=Pyrococ... | 238 | 1e-33 | 127 | 33 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:HAMAP. | | | | | | | | | | GO:0004298; F:threonine-type endopeptidase activity; IEA:HAMAP. | | | | | | | | | | GO:0010498; P:proteasomal protein catabolic process; IEA:HAMAP.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
