| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P32501 | 712 | EI2BE_YEAST Translation initiation factor eIF... | 728 | 0 | 954 | 65 | 78 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IGI:SGD. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 2 | P87163 | 732 | EI2BE_CANAL Translation initiation factor eIF... | 735 | 0 | 768 | 54 | 70 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:CGD. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:CGD. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 3 | P56287 | 678 | EI2BE_SCHPO Probable translation initiation f... | 706 | 0 | 550 | 43 | 62 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 4 | Q54RF3 | 707 | EI2BE_DICDI Translation initiation factor eIF... | 434 | 3e-107 | 349 | 41 | 63 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.::GO:0043614; C:multi-eIF complex; ISS:dictyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:dictyBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 5 | Q64350 | 716 | EI2BE_RAT Translation initiation factor eIF-2... | 722 | 6e-102 | 335 | 31 | 51 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; TAS:RGD.::GO:0031369; F:translation initiation factor binding; IDA:RGD. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 6 | P47823 | 721 | EI2BE_RABIT Translation initiation factor eIF... | 711 | 1e-97 | 324 | 30 | 51 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 7 | Q8CHW4 | 717 | EI2BE_MOUSE Translation initiation factor eIF... | 712 | 1e-97 | 323 | 29 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q13144 | 721 | EI2BE_HUMAN Translation initiation factor eIF... | 714 | 1e-95 | 318 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.::GO:0031369; F:translation initiation factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0014002; P:astrocyte development; IMP:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 9 | P37820 | 359 | MPG1_SULAC Putative mannose-1-phosphate guany... | 403 | 2e-19 | 94.4 | 24 | 44 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 10 | A3QMC8 | 365 | GMPPB_CAEEL Mannose-1-phosphate guanyltransfe... | 393 | 0.00000000000001 | 80.1 | 23 | 43 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 11 | P70541 | 452 | EI2BG_RAT Translation initiation factor eIF-2... | 451 | 0.0000000007 | 65.5 | 21 | 41 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB. | 12 | A6LJL4 | 412 | GLGC_THEM4 Glucose-1-phosphate adenylyltransf... | 430 | 0.000000001 | 64.7 | 22 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 13 | Q8BTZ7 | 360 | GMPPB_MOUSE Mannose-1-phosphate guanyltransfe... | 409 | 0.000000002 | 63.5 | 21 | 40 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 14 | Q5B1J4 | 364 | MPG1_EMENI Mannose-1-phosphate guanyltransfer... | 429 | 0.000000005 | 62.4 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 15 | O74624 | 364 | MPG1_HYPJE Mannose-1-phosphate guanyltransfer... | 415 | 0.000000006 | 62 | 21 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 16 | Q68EQ1 | 360 | GMPPB_XENTR Mannose-1-phosphate guanyltransfe... | 407 | 0.000000006 | 62 | 21 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 17 | P80361 | 404 | EI2BG_CAEEL Probable translation initiation f... | 425 | 0.000000007 | 62.4 | 20 | 41 | GO:0005737; C:cytoplasm; IDA:WormBase. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase. | 18 | A2VD83 | 360 | GMPBB_XENLA Mannose-1-phosphate guanyltransfe... | 413 | 0.000000007 | 62 | 20 | 39 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 19 | P0C5I2 | 360 | GMPPB_PIG Mannose-1-phosphate guanyltransfera... | 407 | 0.000000008 | 61.6 | 21 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IDA:MGI. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 20 | B7IFV2 | 412 | GLGC_THEAB Glucose-1-phosphate adenylyltransf... | 302 | 0.000000009 | 62 | 24 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 21 | Q4U3E8 | 364 | MPG1_ASPFU Mannose-1-phosphate guanyltransfer... | 430 | 0.00000001 | 61.6 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 22 | Q4I1Y5 | 364 | MPG1_GIBZE Mannose-1-phosphate guanyltransfer... | 421 | 0.00000002 | 60.8 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 23 | Q68EY9 | 360 | GMPBA_XENLA Mannose-1-phosphate guanyltransfe... | 407 | 0.00000002 | 60.5 | 20 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 24 | Q8DT53 | 379 | GLGC_STRMU Glucose-1-phosphate adenylyltransf... | 416 | 0.00000002 | 60.5 | 21 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 25 | Q2UJU5 | 364 | MPG1_ASPOR Mannose-1-phosphate guanyltransfer... | 434 | 0.00000002 | 60.5 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 26 | Q6DBU5 | 360 | GMPPB_DANRE Mannose-1-phosphate guanyltransfe... | 408 | 0.00000003 | 60.1 | 22 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 27 | A5PJI7 | 452 | EI2BG_BOVIN Translation initiation factor eIF... | 439 | 0.00000003 | 60.5 | 21 | 40 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 28 | Q9P8N0 | 364 | MPG1_PICAN Mannose-1-phosphate guanyltransfer... | 409 | 0.00000003 | 60.1 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 29 | Q96IJ6 | 420 | GMPPA_HUMAN Mannose-1-phosphate guanyltransfe... | 399 | 0.00000007 | 58.9 | 21 | 43 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 30 | Q86HG0 | 412 | GMPPA_DICDI Mannose-1-phosphate guanyltransfe... | 390 | 0.00000008 | 58.9 | 23 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; ISS:dictyBase. | | | | | | | | | | GO:0009298; P:GDP-mannose biosynthetic process; ISS:dictyBase. | 31 | Q6CCU3 | 363 | MPG1_YARLI Mannose-1-phosphate guanyltransfer... | 400 | 0.00000008 | 58.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. |
