| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | B5VMS9 | 1265 | SDC25_YEAS6 Guanine nucleotide exchange facto... | 223 | 0.000000000001 | 77 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 32 | B3LTF3 | 1252 | SDC25_YEAS1 Guanine nucleotide exchange facto... | 223 | 0.000000000001 | 76.6 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 33 | P0CF34 | 1048 | YL017_YEAST Putative guanine nucleotide excha... | 221 | 0.000000000001 | 76.6 | 29 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 34 | P0CF32 | 1253 | SDC25_YEASX Guanine nucleotide exchange facto... | 223 | 0.000000000002 | 76.3 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 35 | A2AR50 | 585 | RGPS1_MOUSE Ras-specific guanine nucleotide-r... | 115 | 0.000000000003 | 75.1 | 34 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 36 | A2CEA7 | 1244 | RGRF2_DANRE Ras-specific guanine nucleotide-r... | 244 | 0.000000000003 | 75.1 | 24 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 37 | C8ZCV7 | 1252 | SDC25_YEAS8 Guanine nucleotide exchange facto... | 223 | 0.000000000004 | 75.1 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 38 | Q8WZA2 | 1011 | RPGF4_HUMAN Rap guanine nucleotide exchange f... | 201 | 0.000000000006 | 74.3 | 25 | 50 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0030552; F:cAMP binding; ISS:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 39 | Q54TK8 | 1502 | GEFP_DICDI Ras guanine nucleotide exchange fa... | 214 | 0.00000000002 | 72.8 | 27 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 40 | Q54S40 | 1312 | GBPD_DICDI Cyclic GMP-binding protein D OS=Di... | 174 | 0.00000000004 | 71.6 | 24 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:dictyBase. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0051272; P:positive regulation of cellular component movement; TAS:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.::GO:0031275; P:regulation of lateral pseudopodium assembly; IMP:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 41 | Q8IS14 | 812 | GEFJ_DICDI Ras guanine nucleotide exchange fa... | 218 | 0.00000000005 | 70.9 | 27 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 42 | Q55GH9 | 1172 | GEFW_DICDI Ras guanine nucleotide exchange fa... | 216 | 0.00000000006 | 71.2 | 26 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 43 | Q9EQZ6 | 1011 | RPGF4_MOUSE Rap guanine nucleotide exchange f... | 201 | 0.00000000006 | 70.9 | 25 | 49 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0030552; F:cAMP binding; IDA:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 44 | Q8IS15 | 824 | GEFI_DICDI Ras guanine nucleotide exchange fa... | 253 | 0.00000000007 | 70.5 | 25 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 45 | B0M0P8 | 2356 | GEFL_DICDI Ras guanine nucleotide exchange fa... | 212 | 0.00000000008 | 70.9 | 28 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0043052; P:thermotaxis; IMP:dictyBase. | 46 | Q8IS11 | 944 | GEFO_DICDI Ras guanine nucleotide exchange fa... | 187 | 0.0000000003 | 68.9 | 29 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 47 | P26674 | 911 | STE6_SCHPO Protein ste6 OS=Schizosaccharomyce... | 179 | 0.0000000003 | 68.6 | 27 | 49 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 48 | Q03386 | 895 | GNDS_RAT Ral guanine nucleotide dissociation ... | 111 | 0.28 | 39.3 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; TAS:RGD. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:RGD. | 49 | Q8C0Q9 | 814 | RPGF5_MOUSE Rap guanine nucleotide exchange f... | 192 | 0.000000001 | 66.2 | 28 | 48 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030742; F:GTP-dependent protein binding; ISS:UniProtKB.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 50 | P83900 | 580 | RPGF5_RAT Rap guanine nucleotide exchange fac... | 190 | 0.000000004 | 64.7 | 27 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 51 | Q9Z1C7 | 436 | RPGF4_RAT Rap guanine nucleotide exchange fac... | 146 | 0.000000004 | 64.3 | 25 | 51 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0030424; C:axon; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0001917; C:photoreceptor inner segment; IDA:RGD.::GO:0001750; C:photoreceptor outer segment; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0030552; F:cAMP binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007507; P:heart development; IEP:RGD.::GO:0050805; P:negative regulation of synaptic transmission; IDA:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IDA:RGD.::GO:0050773; P:regulation of dendrite development; IMP:RGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 52 | Q9P212 | 2302 | PLCE1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 134 | 0.000000006 | 64.7 | 25 | 48 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:UniProtKB.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0017016; F:Ras GTPase binding; TAS:UniProtKB.::GO:0005057; F:receptor signaling protein activity; TAS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.::GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; IDA:UniProtKB.::GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; NAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006651; P:diacylglycerol biosynthetic process; TAS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0032835; P:glomerulus development; IMP:HGNC.::GO:0007507; P:heart development; TAS:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006644; P:phospholipid metabolic process; IC:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.::GO:0046578; P:regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB. | 53 | O77086 | 1571 | C3G_DROME Guanine nucleotide-releasing factor... | 234 | 0.000000007 | 64.3 | 23 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016203; P:muscle attachment; IMP:FlyBase.::GO:0007265; P:Ras protein signal transduction; IMP:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; IDA:FlyBase.::GO:0045214; P:sarcomere organization; IMP:FlyBase.::GO:0007525; P:somatic muscle development; IMP:FlyBase. | 54 | Q03385 | 852 | GNDS_MOUSE Ral guanine nucleotide dissociatio... | 232 | 0.000000008 | 63.9 | 22 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 55 | Q92565 | 580 | RPGF5_HUMAN Rap guanine nucleotide exchange f... | 190 | 0.000000009 | 63.5 | 27 | 49 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB. | 56 | P0C643 | 608 | GRP2_RAT RAS guanyl-releasing protein 2 OS=Ra... | 132 | 0.00000001 | 63.2 | 30 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 57 | Q9QUG9 | 608 | GRP2_MOUSE RAS guanyl-releasing protein 2 OS=... | 132 | 0.00000001 | 63.2 | 30 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 58 | Q55EC7 | 960 | GEFX_DICDI RasGEF domain-containing serine/th... | 73 | 0.26 | 39.3 | 30 | 56 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 59 | A6N9I4 | 608 | GRP2_BOVIN RAS guanyl-releasing protein 2 OS=... | 132 | 0.00000002 | 62.4 | 30 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 60 | Q3UYI5 | 709 | RGL3_MOUSE Ral guanine nucleotide dissociatio... | 269 | 0.00000003 | 62 | 21 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0017016; F:Ras GTPase binding; IDA:MGI. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:MGI. | 61 | Q7LDG7 | 609 | GRP2_HUMAN RAS guanyl-releasing protein 2 OS=... | 132 | 0.00000004 | 61.2 | 30 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. |
