rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q14432 | 1141 | PDE3A_HUMAN cGMP-inhibited 3',5'-cyclic phosp... | 192 | 0.004 | 43.9 | 26 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004119; F:cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.::GO:0071321; P:cellular response to cGMP; IDA:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0019934; P:cGMP-mediated signaling; IMP:UniProtKB.::GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0043116; P:negative regulation of vascular permeability; IMP:UniProtKB.::GO:0043117; P:positive regulation of vascular permeability; IMP:UniProtKB. | 92 | Q63085 | 1108 | PDE3B_RAT cGMP-inhibited 3',5'-cyclic phospho... | 169 | 0.009 | 42.7 | 27 | 40 | GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:RGD.::GO:0030552; F:cAMP binding; IDA:RGD.::GO:0004119; F:cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; IDA:RGD.::GO:0008144; F:drug binding; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IDA:RGD.::GO:0043422; F:protein kinase B binding; ISS:BHF-UCL. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IDA:RGD.::GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0046676; P:negative regulation of insulin secretion; IMP:RGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 93 | P91119 | 728 | PDE5_CAEEL Probable 3',5'-cyclic phosphodiest... | 137 | 0.011 | 42.4 | 28 | 45 | | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000003; P:reproduction; IMP:WormBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 94 | Q61409 | 1100 | PDE3B_MOUSE cGMP-inhibited 3',5'-cyclic phosp... | 161 | 0.012 | 42 | 27 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0043422; F:protein kinase B binding; IPI:BHF-UCL. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IEP:BHF-UCL.::GO:0031018; P:endocrine pancreas development; IDA:MGI.::GO:0042593; P:glucose homeostasis; IDA:MGI.::GO:0050796; P:regulation of insulin secretion; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 95 | P30645 | 831 | PDE2_CAEEL Probable 3',5'-cyclic phosphodiest... | 210 | 0.047 | 40 | 26 | 41 | | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 96 | A4ZUD6 | 150 | Y150A_ABVP Uncharacterized protein ORF150a OS... | 74 | 4.3 | 32.7 | 27 | 57 | | | | | | | | | | | | | | | | | | | | | | 97 | A5IJJ8 | 1367 | DPO3_THEP1 DNA polymerase III polC-type OS=Th... | 43 | 5.7 | 33.5 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 98 | Q9ZHF6 | 1367 | DPO3_THEMA DNA polymerase III polC-type OS=Th... | 43 | 6.3 | 33.5 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. |