| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9W4T0 | 903 | PDE4D_DROME cAMP-specific 3',5'-cyclic phosph... | 333 | 0.000000000005 | 72 | 26 | 40 | | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048675; P:axon extension; IMP:FlyBase.::GO:0048149; P:behavioral response to ethanol; NAS:FlyBase.::GO:0019933; P:cAMP-mediated signaling; NAS:FlyBase.::GO:0001661; P:conditioned taste aversion; IMP:FlyBase.::GO:0007619; P:courtship behavior; TAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0046958; P:nonassociative learning; TAS:FlyBase.::GO:0008355; P:olfactory learning; TAS:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0007268; P:synaptic transmission; IMP:FlyBase. | 32 | Q8IRU4 | 662 | PDE4E_DROME cAMP-specific 3',5'-cyclic phosph... | 332 | 0.000000000006 | 71.6 | 26 | 39 | | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048675; P:axon extension; IMP:FlyBase.::GO:0048149; P:behavioral response to ethanol; NAS:FlyBase.::GO:0019933; P:cAMP-mediated signaling; NAS:FlyBase.::GO:0001661; P:conditioned taste aversion; IMP:FlyBase.::GO:0007619; P:courtship behavior; TAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0046958; P:nonassociative learning; TAS:FlyBase.::GO:0008355; P:olfactory learning; TAS:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0007268; P:synaptic transmission; IMP:FlyBase. | 33 | Q01063 | 747 | PDE4D_MOUSE cAMP-specific 3',5'-cyclic phosph... | 292 | 0.000000000008 | 71.6 | 26 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IMP:MGI.::GO:0061028; P:establishment of endothelial barrier; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006939; P:smooth muscle contraction; IMP:MGI. | 34 | P52731 | 862 | PDE6C_CHICK Cone cGMP-specific 3',5'-cyclic p... | 346 | 0.000000000008 | 71.6 | 24 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 35 | P11541 | 859 | PDE6A_BOVIN Rod cGMP-specific 3',5'-cyclic ph... | 358 | 0.000000000008 | 71.6 | 23 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 36 | Q28263 | 861 | PDE6A_CANFA Rod cGMP-specific 3',5'-cyclic ph... | 342 | 0.000000000009 | 71.2 | 23 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 37 | Q9W4T4 | 1209 | PDE4A_DROME cAMP-specific 3',5'-cyclic phosph... | 333 | 0.00000000001 | 71.6 | 26 | 40 | | | | | | | | | | | GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048675; P:axon extension; IMP:FlyBase.::GO:0048149; P:behavioral response to ethanol; NAS:FlyBase.::GO:0019933; P:cAMP-mediated signaling; NAS:FlyBase.::GO:0001661; P:conditioned taste aversion; IMP:FlyBase.::GO:0007619; P:courtship behavior; TAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0046958; P:nonassociative learning; TAS:FlyBase.::GO:0008355; P:olfactory learning; TAS:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0007268; P:synaptic transmission; IMP:FlyBase. | 38 | Q91ZQ1 | 861 | PDE6C_MOUSE Cone cGMP-specific 3',5'-cyclic p... | 341 | 0.00000000002 | 70.5 | 23 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007603; P:phototransduction, visible light; IMP:MGI.::GO:0046549; P:retinal cone cell development; IMP:MGI.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 39 | Q9HCR9 | 933 | PDE11_HUMAN Dual 3',5'-cyclic-AMP and -GMP ph... | 276 | 0.00000000002 | 70.5 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IDA:UniProtKB.::GO:0004118; F:cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc. | 40 | P14270 | 803 | PDE4D_RAT cAMP-specific 3',5'-cyclic phosphod... | 293 | 0.00000000002 | 70.5 | 26 | 41 | GO:0000267; C:cell fraction; IDA:RGD.::GO:0005813; C:centrosome; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0030016; C:myofibril; IDA:RGD. | | | | | | | | | | GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:RGD.::GO:0030552; F:cAMP binding; IMP:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.::GO:0043623; P:cellular protein complex assembly; IDA:RGD.::GO:0061028; P:establishment of endothelial barrier; IDA:UniProtKB.::GO:0007613; P:memory; IEP:RGD.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:RGD.::GO:0010738; P:regulation of protein kinase A signaling cascade; IMP:RGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 41 | P27664 | 859 | PDE6A_MOUSE Rod cGMP-specific 3',5'-cyclic ph... | 342 | 0.00000000002 | 70.5 | 23 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 42 | Q08499 | 809 | PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosph... | 293 | 0.00000000004 | 69.3 | 26 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; TAS:ProtInc.::GO:0030552; F:cAMP binding; IDA:UniProtKB.::GO:0008144; F:drug binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IMP:UniProtKB.::GO:0061028; P:establishment of endothelial barrier; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 43 | P0C1Q2 | 933 | PDE11_MOUSE Dual 3',5'-cyclic-AMP and -GMP ph... | 276 | 0.00000000004 | 69.3 | 25 | 45 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; ISS:UniProtKB.::GO:0004118; F:cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 44 | P16499 | 860 | PDE6A_HUMAN Rod cGMP-specific 3',5'-cyclic ph... | 358 | 0.00000000005 | 68.9 | 22 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IMP:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051480; P:cytosolic calcium ion homeostasis; IMP:BHF-UCL.::GO:0046037; P:GMP metabolic process; IMP:BHF-UCL.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007601; P:visual perception; TAS:ProtInc. | 45 | B4JXX2 | 1078 | PDE6_DROGR cGMP-specific 3',5'-cyclic phospho... | 276 | 0.00000000007 | 68.6 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 46 | Q8VID6 | 935 | PDE11_RAT Dual 3',5'-cyclic-AMP and -GMP phos... | 276 | 0.00000000008 | 68.6 | 25 | 45 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030552; F:cAMP binding; IDA:RGD.::GO:0030553; F:cGMP binding; IDA:RGD.::GO:0004118; F:cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IDA:RGD.::GO:0046069; P:cGMP catabolic process; IDA:RGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 47 | Q01065 | 535 | PDE1B_MOUSE Calcium/calmodulin-dependent 3',5... | 239 | 0.00000000008 | 67.8 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0042053; P:regulation of dopamine metabolic process; IMP:MGI.::GO:0001505; P:regulation of neurotransmitter levels; IMP:MGI.::GO:0001975; P:response to amphetamine; IMP:MGI.::GO:0042428; P:serotonin metabolic process; IMP:MGI.::GO:0007165; P:signal transduction; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 48 | B3P3K2 | 1131 | PDE6_DROER cGMP-specific 3',5'-cyclic phospho... | 276 | 0.00000000008 | 68.6 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 49 | Q01066 | 535 | PDE1B_RAT Calcium/calmodulin-dependent 3',5'-... | 239 | 0.00000000008 | 67.8 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:RGD.::GO:0048101; F:calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IDA:RGD.::GO:0046069; P:cGMP catabolic process; IDA:RGD. | 50 | Q9VFI9 | 1118 | PDE6_DROME cGMP-specific 3',5'-cyclic phospho... | 276 | 0.00000000009 | 68.6 | 25 | 45 | GO:0016324; C:apical plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; IDA:UniProtKB.::GO:0032240; P:negative regulation of nucleobase-containing compound transport; IMP:FlyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 51 | B4QZU1 | 1143 | PDE6_DROSI cGMP-specific 3',5'-cyclic phospho... | 276 | 0.00000000009 | 68.2 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 52 | B4PSS5 | 1149 | PDE6_DROYA cGMP-specific 3',5'-cyclic phospho... | 276 | 0.0000000001 | 68.2 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 53 | B4LVU6 | 893 | PDE6_DROVI cGMP-specific 3',5'-cyclic phospho... | 276 | 0.0000000001 | 68.2 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 54 | B3LVW5 | 1158 | PDE6_DROAN cGMP-specific 3',5'-cyclic phospho... | 276 | 0.0000000001 | 68.2 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 55 | Q01064 | 536 | PDE1B_HUMAN Calcium/calmodulin-dependent 3',5... | 239 | 0.0000000001 | 67.4 | 29 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004117; F:calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.::GO:0097011; P:cellular response to granulocyte macrophage colony-stimulating factor stimulus; IDA:UniProtKB.::GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IDA:UniProtKB.::GO:0046069; P:cGMP catabolic process; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0030224; P:monocyte differentiation; IEP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome. | 56 | B4K9L4 | 1116 | PDE6_DROMO cGMP-specific 3',5'-cyclic phospho... | 276 | 0.0000000001 | 67.8 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 57 | B4NAL6 | 1127 | PDE6_DROWI cGMP-specific 3',5'-cyclic phospho... | 276 | 0.0000000001 | 67.8 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046068; P:cGMP metabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 58 | P16586 | 855 | PDE6C_BOVIN Cone cGMP-specific 3',5'-cyclic p... | 346 | 0.0000000002 | 67.4 | 24 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 59 | Q22000 | 674 | PDE4_CAEEL Probable 3',5'-cyclic phosphodiest... | 295 | 0.0000000003 | 66.2 | 26 | 43 | GO:0045202; C:synapse; IDA:WormBase. | | | | | | | | | | GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; ISS:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; ISS:WormBase.::GO:0043951; P:negative regulation of cAMP-mediated signaling; IGI:WormBase.::GO:0040013; P:negative regulation of locomotion; IMP:WormBase.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030431; P:sleep; IMP:WormBase. | 60 | Q1KKS3 | 903 | PDE11_TAKRU Dual 3',5'-cyclic-AMP and -GMP ph... | 273 | 0.0000000008 | 65.1 | 26 | 42 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 61 | P54748 | 844 | PDE4A_RAT cAMP-specific 3',5'-cyclic phosphod... | 299 | 0.0000000009 | 65.1 | 25 | 41 | GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0007165; P:signal transduction; IEA:InterPro. |
