| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P97489 | 404 | GATA5_MOUSE Transcription factor GATA-5 OS=Mu... | 39 | 0.000000002 | 64.3 | 62 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071773; P:cellular response to BMP stimulus; IDA:MGI. | 32 | P46152 | 440 | GATA4_RAT Transcription factor GATA-4 OS=Ratt... | 39 | 0.000000003 | 63.5 | 59 | 74 | GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0051525; F:NFAT protein binding; IPI:RGD.::GO:0008270; F:zinc ion binding; TAS:RGD. | | | | | | | | | | GO:0061049; P:cell growth involved in cardiac muscle cell development; IDA:RGD.::GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.::GO:0010507; P:negative regulation of autophagy; IMP:RGD.::GO:0030513; P:positive regulation of BMP signaling pathway; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0009612; P:response to mechanical stimulus; IDA:RGD. | 33 | P23773 | 435 | GATA3_XENLA GATA-binding factor 3 OS=Xenopus ... | 101 | 0.00000000003 | 69.7 | 38 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | P23772 | 443 | GATA3_MOUSE Trans-acting T-cell-specific tran... | 91 | 0.000000007 | 62.4 | 41 | 52 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0005134; F:interleukin-2 receptor binding; IPI:MGI.::GO:0046983; F:protein dimerization activity; IDA:MGI.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003180; P:aortic valve morphogenesis; IMP:UniProtKB.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; IMP:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:UniProtKB.::GO:0001709; P:cell fate determination; IDA:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0071773; P:cellular response to BMP stimulus; IDA:MGI.::GO:0071353; P:cellular response to interleukin-4; IEP:UniProtKB.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0035162; P:embryonic hemopoiesis; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IDA:MGI.::GO:0006959; P:humoral immune response; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0072643; P:interferon-gamma secretion; IMP:MGI.::GO:0072602; P:interleukin-4 secretion; IMP:MGI.::GO:0002088; P:lens development in camera-type eye; IMP:MGI.::GO:0072676; P:lymphocyte migration; ISS:UniProtKB.::GO:0008584; P:male gonad development; IMP:UniProtKB.::GO:0060374; P:mast cell differentiation; IDA:MGI.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0001823; P:mesonephros development; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; IMP:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; IMP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; IDA:MGI.::GO:0032703; P:negative regulation of interleukin-2 production; IDA:MGI.::GO:0072179; P:nephric duct formation; IMP:UniProtKB.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0042421; P:norepinephrine biosynthetic process; IMP:MGI.::GO:0071599; P:otic vesicle development; IMP:MGI.::GO:0060017; P:parathyroid gland development; IMP:MGI.::GO:0035898; P:parathyroid hormone secretion; IMP:MGI.::GO:0060037; P:pharyngeal system development; IMP:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0032736; P:positive regulation of interleukin-13 production; IMP:MGI.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; IDA:MGI.::GO:0032754; P:positive regulation of interleukin-5 production; IMP:MGI.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; IDA:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IMP:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; IMP:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0002572; P:pro-T cell differentiation; IMP:MGI.::GO:0043370; P:regulation of CD4-positive, alpha-beta T cell differentiation; IMP:MGI.::GO:2000683; P:regulation of cellular response to X-ray; ISS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; IDA:MGI.::GO:2000114; P:regulation of establishment of cell polarity; IDA:MGI.::GO:0061085; P:regulation of histone H3-K27 methylation; IDA:MGI.::GO:0051569; P:regulation of histone H3-K4 methylation; IDA:MGI.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; IMP:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; IMP:MGI.::GO:0048485; P:sympathetic nervous system development; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.::GO:0045064; P:T-helper 2 cell differentiation; IDA:MGI.::GO:0045061; P:thymic T cell selection; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.::GO:0035799; P:ureter maturation; IMP:MGI.::GO:0060676; P:ureteric bud formation; IMP:UniProtKB.::GO:0060065; P:uterus development; IMP:UniProtKB.::GO:0003281; P:ventricular septum development; IMP:UniProtKB. | 35 | Q92908 | 595 | GATA6_HUMAN Transcription factor GATA-6 OS=Ho... | 39 | 0.000000004 | 63.9 | 59 | 79 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0060947; P:cardiac vascular smooth muscle cell differentiation; IMP:UniProtKB.::GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0060575; P:intestinal epithelial cell differentiation; IDA:MGI.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:UniProtKB.::GO:0032912; P:negative regulation of transforming growth factor beta2 production; IMP:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; IMP:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB. | 36 | P23825 | 444 | GATA3_CHICK GATA-binding factor 3 OS=Gallus g... | 85 | 0.00000001 | 61.6 | 41 | 52 | GO:0000790; C:nuclear chromatin; ISS:UniProtKB. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.::GO:0042491; P:auditory receptor cell differentiation; IEP:UniProtKB.::GO:0007411; P:axon guidance; NAS:UniProtKB.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; ISS:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.::GO:0001709; P:cell fate determination; ISS:UniProtKB.::GO:0072676; P:lymphocyte migration; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0072179; P:nephric duct formation; ISS:UniProtKB.::GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.::GO:0060037; P:pharyngeal system development; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.::GO:2000683; P:regulation of cellular response to X-ray; ISS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0031929; P:TOR signaling cascade; ISS:UniProtKB.::GO:0060676; P:ureteric bud formation; ISS:UniProtKB.::GO:0060065; P:uterus development; ISS:UniProtKB.::GO:0003281; P:ventricular septum development; ISS:UniProtKB. | 37 | Q08369 | 440 | GATA4_MOUSE Transcription factor GATA-4 OS=Mu... | 39 | 0.000000005 | 62.8 | 59 | 74 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:MGI.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.::GO:0003181; P:atrioventricular valve morphogenesis; TAS:BHF-UCL.::GO:0030509; P:BMP signaling pathway; IDA:MGI.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:MGI.::GO:0055007; P:cardiac muscle cell differentiation; IEP:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:BHF-UCL.::GO:0007267; P:cell-cell signaling; IMP:MGI.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IDA:MGI.::GO:0060540; P:diaphragm morphogenesis; TAS:BHF-UCL.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0048617; P:embryonic foregut morphogenesis; IMP:MGI.::GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IMP:MGI.::GO:0003197; P:endocardial cushion development; IMP:BHF-UCL.::GO:0001706; P:endoderm formation; IMP:MGI.::GO:0072148; P:epithelial cell fate commitment; IMP:MGI.::GO:0001702; P:gastrulation with mouth forming second; IMP:MGI.::GO:0001947; P:heart looping; IMP:BHF-UCL.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0060464; P:lung lobe formation; IMP:MGI.::GO:0003192; P:mitral valve formation; TAS:BHF-UCL.::GO:0003151; P:outflow tract morphogenesis; TAS:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IDA:BHF-UCL.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0051891; P:positive regulation of cardioblast differentiation; IEP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:MGI.::GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.::GO:0072520; P:seminiferous tubule development; IMP:MGI.::GO:0060008; P:Sertoli cell differentiation; IMP:MGI.::GO:0023019; P:signal transduction involved in regulation of gene expression; IDA:MGI.::GO:0035914; P:skeletal muscle cell differentiation; IEP:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0003195; P:tricuspid valve formation; TAS:BHF-UCL.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.::GO:0003229; P:ventricular cardiac muscle tissue development; IGI:MGI.::GO:0003281; P:ventricular septum development; IMP:BHF-UCL. | 38 | P23771 | 443 | GATA3_HUMAN Trans-acting T-cell-specific tran... | 90 | 0.000000008 | 62.4 | 41 | 52 | GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; ISS:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.::GO:0001709; P:cell fate determination; ISS:UniProtKB.::GO:0035457; P:cellular response to interferon-alpha; IEP:UniProtKB.::GO:0071353; P:cellular response to interleukin-4; IEP:UniProtKB.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.::GO:0006952; P:defense response; TAS:ProtInc.::GO:0043583; P:ear development; IMP:UniProtKB.::GO:0072676; P:lymphocyte migration; IDA:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; IDA:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.::GO:2000146; P:negative regulation of cell motility; IMP:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IMP:UniProtKB.::GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IDA:UniProtKB.::GO:0072179; P:nephric duct formation; ISS:UniProtKB.::GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.::GO:0060037; P:pharyngeal system development; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; IDA:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IMP:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.::GO:2000683; P:regulation of cellular response to X-ray; IMP:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IEP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0031929; P:TOR signaling cascade; ISS:UniProtKB.::GO:0060676; P:ureteric bud formation; ISS:UniProtKB.::GO:0060065; P:uterus development; ISS:UniProtKB.::GO:0003281; P:ventricular septum development; ISS:UniProtKB. | 39 | P23824 | 466 | GATA2_CHICK GATA-binding factor 2 OS=Gallus g... | 39 | 0.00000003 | 60.8 | 59 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 40 | P17678 | 304 | GATA1_CHICK Erythroid transcription factor OS... | 51 | 0.00000007 | 58.5 | 51 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 41 | Q61169 | 589 | GATA6_MOUSE Transcription factor GATA-6 OS=Mu... | 63 | 0.00000000007 | 69.3 | 46 | 60 | GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0055007; P:cardiac muscle cell differentiation; IEP:BHF-UCL.::GO:0071773; P:cellular response to BMP stimulus; IDA:MGI.::GO:0071371; P:cellular response to gonadotropin stimulus; IDA:MGI.::GO:0060486; P:Clara cell differentiation; IGI:MGI.::GO:0007493; P:endodermal cell fate determination; IDA:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0060430; P:lung saccule development; IGI:MGI.::GO:0048645; P:organ formation; IMP:MGI.::GO:0003310; P:pancreatic A cell differentiation; IMP:MGI.::GO:0006644; P:phospholipid metabolic process; IGI:MGI.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0051891; P:positive regulation of cardioblast differentiation; IEP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:MGI.::GO:0035239; P:tube morphogenesis; IGI:MGI.::GO:0003309; P:type B pancreatic cell differentiation; IMP:MGI.::GO:0060510; P:Type II pneumocyte differentiation; IGI:MGI. | 42 | P70005 | 391 | GAT6B_XENLA GATA-binding factor 6-B OS=Xenopu... | 39 | 0.000000003 | 63.5 | 59 | 79 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035051; P:cardiac cell differentiation; IMP:UniProtKB.::GO:0048738; P:cardiac muscle tissue development; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | P43696 | 388 | GAT5B_XENLA GATA-binding factor 5-B OS=Xenopu... | 39 | 0.000000003 | 63.2 | 59 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | P43695 | 390 | GAT5A_XENLA GATA-binding factor 5-A OS=Xenopu... | 39 | 0.000000004 | 63.2 | 59 | 74 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 45 | P91623 | 486 | GATAC_DROME GATA-binding factor C OS=Drosophi... | 56 | 0.00000000008 | 68.9 | 52 | 66 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009887; P:organ morphogenesis; IMP:FlyBase.::GO:0009888; P:tissue development; IMP:FlyBase. | 46 | P46153 | 587 | GATA6_RAT Transcription factor GATA-6 OS=Ratt... | 39 | 0.000000005 | 63.2 | 59 | 79 | | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042475; P:odontogenesis of dentin-containing tooth; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0030513; P:positive regulation of BMP signaling pathway; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 47 | P23770 | 452 | GATA2_XENLA GATA-binding factor 2 OS=Xenopus ... | 39 | 0.00000004 | 60.1 | 59 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 48 | Q08DV0 | 443 | GATA3_BOVIN Trans-acting T-cell-specific tran... | 84 | 0.00000001 | 61.6 | 42 | 52 | GO:0000790; C:nuclear chromatin; ISS:UniProtKB. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; ISS:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.::GO:0001709; P:cell fate determination; ISS:UniProtKB.::GO:0072676; P:lymphocyte migration; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0072179; P:nephric duct formation; ISS:UniProtKB.::GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.::GO:0060037; P:pharyngeal system development; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.::GO:2000683; P:regulation of cellular response to X-ray; ISS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0031929; P:TOR signaling cascade; ISS:UniProtKB.::GO:0060676; P:ureteric bud formation; ISS:UniProtKB.::GO:0060065; P:uterus development; ISS:UniProtKB.::GO:0003281; P:ventricular septum development; ISS:UniProtKB. | 49 | P23768 | 364 | GAT1B_XENLA GATA-binding factor 1-B OS=Xenopu... | 107 | 0.0000000001 | 67.4 | 36 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 50 | P23767 | 359 | GAT1A_XENLA GATA-binding factor 1-A OS=Xenopu... | 107 | 0.0000000002 | 67.4 | 36 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q924Y4 | 480 | GATA2_RAT Endothelial transcription factor GA... | 39 | 0.00000004 | 60.5 | 59 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006909; P:phagocytosis; IDA:RGD.::GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB. | 52 | P23769 | 480 | GATA2_HUMAN Endothelial transcription factor ... | 39 | 0.00000005 | 60.1 | 59 | 72 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0070742; F:C2H2 zinc finger domain binding; IPI:BHF-UCL.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0035854; P:eosinophil fate commitment; IDA:BHF-UCL.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.::GO:0070345; P:negative regulation of fat cell proliferation; IMP:UniProtKB.::GO:2000178; P:negative regulation of neural precursor cell proliferation; IDA:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0045766; P:positive regulation of angiogenesis; IDA:MGI.::GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB. | 53 | O09100 | 480 | GATA2_MOUSE Endothelial transcription factor ... | 39 | 0.00000005 | 60.1 | 59 | 72 | GO:0005634; C:nucleus; IDA:MGI.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021533; P:cell differentiation in hindbrain; IMP:MGI.::GO:0001709; P:cell fate determination; IDA:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IMP:MGI.::GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:MGI.::GO:0045650; P:negative regulation of macrophage differentiation; IDA:MGI.::GO:2000178; P:negative regulation of neural precursor cell proliferation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0048663; P:neuron fate commitment; IMP:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045766; P:positive regulation of angiogenesis; IMP:MGI.::GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0045654; P:positive regulation of megakaryocyte differentiation; IDA:MGI.::GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB.::GO:0035065; P:regulation of histone acetylation; IDA:MGI.::GO:0060872; P:semicircular canal development; IMP:MGI.::GO:0035019; P:somatic stem cell maintenance; IMP:MGI.::GO:0001655; P:urogenital system development; IMP:MGI.::GO:0021514; P:ventral spinal cord interneuron differentiation; IMP:MGI. | 54 | Q9UHF7 | 1281 | TRPS1_HUMAN Zinc finger transcription factor ... | 82 | 0.0000000003 | 67.8 | 45 | 61 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0032330; P:regulation of chondrocyte differentiation; ISS:UniProtKB.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 55 | Q925H1 | 1281 | TRPS1_MOUSE Zinc finger transcription factor ... | 82 | 0.0000000003 | 67.4 | 45 | 61 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032330; P:regulation of chondrocyte differentiation; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 56 | Q90ZS6 | 1271 | TRPS1_XENLA Zinc finger transcription factor ... | 57 | 0.000000001 | 65.9 | 51 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | Q9BWX5 | 397 | GATA5_HUMAN Transcription factor GATA-5 OS=Ho... | 44 | 0.00000001 | 61.2 | 52 | 73 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0060575; P:intestinal epithelial cell differentiation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 58 | Q3SZJ5 | 403 | GATA5_BOVIN Transcription factor GATA-5 OS=Bo... | 64 | 0.00000001 | 61.6 | 44 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 59 | O94720 | 557 | YCF8_SCHPO GATA zinc finger domain-containing... | 59 | 0.000000002 | 64.3 | 47 | 61 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 60 | P43692 | 391 | GATA5_CHICK Transcription factor GATA-5 OS=Ga... | 43 | 0.00000002 | 60.8 | 51 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 61 | P43429 | 413 | GATA1_RAT Erythroid transcription factor OS=R... | 54 | 0.00000004 | 59.7 | 46 | 65 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:RGD.::GO:0031100; P:organ regeneration; IDA:RGD.::GO:0060009; P:Sertoli cell development; IEP:RGD. |
