| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9Y0H4 | 949 | SUDX_DROME E3 ubiquitin-protein ligase Su(dx)... | 31 | 0.015 | 40 | 45 | 71 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0016348; P:imaginal disc-derived leg joint morphogenesis; IMP:UniProtKB.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IGI:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:UniProtKB.::GO:0019915; P:lipid storage; IDA:FlyBase.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.::GO:0007219; P:Notch signaling pathway; IGI:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0035209; P:pupal development; IMP:UniProtKB.::GO:0031623; P:receptor internalization; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:FlyBase.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IMP:UniProtKB. | 32 | Q45VV3 | 418 | YORKI_DROME Protein yorkie OS=Drosophila mela... | 38 | 0.005 | 41.2 | 47 | 63 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:FlyBase. | | | | | | | | | | GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:FlyBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | A2QQ28 | 821 | RSP5_ASPNC Probable E3 ubiquitin-protein liga... | 30 | 0.015 | 40 | 50 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB. | 34 | Q4L1J4 | 1255 | MAGI1_RAT Membrane-associated guanylate kinas... | 56 | 0.061 | 38.1 | 38 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 35 | Q2TAS2 | 751 | SMUF2_XENLA E3 ubiquitin-protein ligase SMURF... | 92 | 0.036 | 38.5 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 36 | Q9HAU4 | 748 | SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF... | 92 | 0.18 | 36.6 | 30 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046332; F:SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; NAS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL. | 37 | A2A5Z6 | 748 | SMUF2_MOUSE E3 ubiquitin-protein ligase SMURF... | 92 | 0.19 | 36.6 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 38 | Q3UIL6 | 1118 | PKHA7_MOUSE Pleckstrin homology domain-contai... | 83 | 0.007 | 40.8 | 31 | 43 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB. | 39 | A4IIJ3 | 1108 | KIBRA_XENTR Protein KIBRA OS=Xenopus tropical... | 99 | 0.017 | 39.7 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 40 | Q6IQ23 | 1121 | PKHA7_HUMAN Pleckstrin homology domain-contai... | 82 | 0.012 | 40 | 32 | 44 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005915; C:zonula adherens; IDA:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.::GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB. | 41 | A9JRZ0 | 765 | SMUF2_DANRE E3 ubiquitin-protein ligase SMURF... | 139 | 0.079 | 37.7 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 42 | Q5F488 | 1128 | MAGI3_CHICK Membrane-associated guanylate kin... | 122 | 0.014 | 40 | 25 | 43 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 43 | Q8IX03 | 1113 | KIBRA_HUMAN Protein KIBRA OS=Homo sapiens (Hu... | 105 | 0.019 | 39.7 | 30 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:Reactome.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0035330; P:regulation of hippo signaling cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | O88382 | 1277 | MAGI2_RAT Membrane-associated guanylate kinas... | 118 | 0.21 | 36.2 | 28 | 42 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0036057; C:slit diaphragm; IDA:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0003094; P:glomerular filtration; IC:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0043113; P:receptor clustering; IDA:RGD.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB. | 45 | Q9WVQ1 | 1275 | MAGI2_MOUSE Membrane-associated guanylate kin... | 118 | 0.47 | 35.4 | 27 | 42 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IPI:MGI.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0070699; F:type II activin receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB. | 46 | Q5SXA9 | 1104 | KIBRA_MOUSE Protein KIBRA OS=Mus musculus (Mo... | 105 | 0.022 | 39.3 | 30 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 47 | Q76N89 | 1606 | HECW1_HUMAN E3 ubiquitin-protein ligase HECW1... | 31 | 0.037 | 38.9 | 45 | 65 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 48 | Q5BIN5 | 163 | PIN1_BOVIN Peptidyl-prolyl cis-trans isomeras... | 55 | 0.039 | 37.4 | 38 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; ISS:AgBase. | 49 | Q8K4P8 | 1604 | HECW1_MOUSE E3 ubiquitin-protein ligase HECW1... | 31 | 0.04 | 38.5 | 45 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 50 | Q13526 | 163 | PIN1_HUMAN Peptidyl-prolyl cis-trans isomeras... | 55 | 0.041 | 37.4 | 38 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:MGI.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IPI:BHF-UCL.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:BHF-UCL.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.::GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2000146; P:negative regulation of cell motility; IDA:BHF-UCL.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:MGI.::GO:0032321; P:positive regulation of Rho GTPase activity; IMP:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0032465; P:regulation of cytokinesis; IMP:MGI.::GO:0007088; P:regulation of mitosis; TAS:ProtInc.::GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL. | 51 | Q803A8 | 412 | WWOX_DANRE WW domain-containing oxidoreductas... | 104 | 1.9 | 33.1 | 24 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 52 | Q9H4B6 | 383 | SAV1_HUMAN Protein salvador homolog 1 OS=Homo... | 97 | 1.2 | 33.9 | 27 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 53 | Q9VCR6 | 608 | SAV_DROME Scaffold protein salvador OS=Drosop... | 77 | 0.058 | 38.1 | 29 | 42 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0051726; P:regulation of cell cycle; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IGI:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; TAS:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0046666; P:retinal cell programmed cell death; IMP:FlyBase.::GO:0048863; P:stem cell differentiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase. | 54 | P46936 | 448 | YAP1_CHICK Yorkie homolog OS=Gallus gallus (C... | 34 | 0.064 | 37.7 | 41 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0071480; P:cellular response to gamma radiation; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | Q54T86 | 568 | DWWA_DICDI WW domain-containing protein A OS=... | 30 | 0.53 | 35 | 40 | 63 | GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IDA:dictyBase.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 56 | Q86UL8 | 1455 | MAGI2_HUMAN Membrane-associated guanylate kin... | 96 | 0.62 | 35 | 27 | 44 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0003402; P:planar cell polarity pathway involved in axis elongation; NAS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB. | 57 | Q8VEB2 | 386 | SAV1_MOUSE Protein salvador homolog 1 OS=Mus ... | 97 | 1.5 | 33.5 | 27 | 38 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0001942; P:hair follicle development; IMP:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0060575; P:intestinal epithelial cell differentiation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060487; P:lung epithelial cell differentiation; IMP:MGI.::GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:2000036; P:regulation of stem cell maintenance; IMP:MGI.::GO:0060412; P:ventricular septum morphogenesis; IMP:MGI. | 58 | A4V8B4 | 387 | SAV1_RAT Protein salvador homolog 1 OS=Rattus... | 97 | 1.5 | 33.5 | 27 | 38 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 59 | Q9HCE7 | 757 | SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF... | 111 | 0.16 | 36.6 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0048185; F:activin binding; IPI:BHF-UCL.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.::GO:0034394; P:protein localization at cell surface; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0032801; P:receptor catabolic process; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL. | 60 | Q6NXJ0 | 1187 | WWC2_MOUSE Protein WWC2 OS=Mus musculus (Mous... | 94 | 0.69 | 34.7 | 30 | 43 | | | | | | | | | | | | | | | | | | | | | | 61 | Q9QUR7 | 165 | PIN1_MOUSE Peptidyl-prolyl cis-trans isomeras... | 55 | 0.17 | 35.4 | 36 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0032465; P:regulation of cytokinesis; IMP:MGI. |
