rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 66 | 0.032 | 40.4 | 30 | 52 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 32 | Q5BBL4 | 581 | HSE1_EMENI Class E vacuolar protein-sorting m... | 78 | 0.041 | 40 | 31 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 33 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 100 | 0.043 | 39.3 | 26 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 34 | A1CEK6 | 599 | HSE1_ASPCL Class E vacuolar protein-sorting m... | 96 | 0.044 | 40 | 32 | 44 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 35 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 69 | 0.045 | 39.7 | 26 | 48 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 36 | Q99K30 | 729 | ES8L2_MOUSE Epidermal growth factor receptor ... | 66 | 0.046 | 40 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 37 | Q0U6X7 | 618 | HSE1_PHANO Class E vacuolar protein-sorting m... | 120 | 0.047 | 39.7 | 27 | 42 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 38 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 78 | 0.061 | 39.7 | 33 | 44 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 39 | Q9Z0R4 | 1714 | ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo... | 64 | 0.063 | 39.7 | 38 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 40 | Q3USJ8 | 740 | FCSD2_MOUSE FCH and double SH3 domains protei... | 61 | 0.065 | 39.3 | 30 | 54 | | | | | | | | | | | | | | | | | | | | | | 41 | O94868 | 740 | FCSD2_HUMAN FCH and double SH3 domains protei... | 61 | 0.068 | 39.3 | 30 | 54 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 42 | P43603 | 459 | LSB3_YEAST LAS seventeen-binding protein 3 OS... | 46 | 0.071 | 39.3 | 37 | 59 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD. | 43 | A7A261 | 459 | LSB3_YEAS7 LAS seventeen-binding protein 3 OS... | 46 | 0.071 | 39.3 | 37 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 44 | Q4WHP5 | 584 | HSE1_ASPFU Class E vacuolar protein-sorting m... | 78 | 0.077 | 39.3 | 31 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 45 | Q63768 | 304 | CRK_RAT Adapter molecule crk OS=Rattus norveg... | 63 | 0.08 | 38.5 | 27 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0051270; P:regulation of cellular component movement; TAS:RGD.::GO:0035020; P:regulation of Rac protein signal transduction; IMP:RGD.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 46 | Q4R729 | 692 | SH321_MACFA SH3 domain-containing protein 21 ... | 52 | 0.081 | 39.3 | 42 | 56 | | | | | | | | | | | | | | | | | | | | | | 47 | O74352 | 466 | HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce... | 58 | 0.081 | 38.9 | 43 | 59 | GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase. | | | | | | | | | | GO:0051020; F:GTPase binding; NAS:PomBase. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 48 | A1DFN5 | 603 | HSE1_NEOFI Class E vacuolar protein-sorting m... | 78 | 0.081 | 38.9 | 31 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 49 | Q08EC4 | 804 | CASS4_MOUSE Cas scaffolding protein family me... | 80 | 0.086 | 38.9 | 30 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 50 | P32793 | 468 | YSC84_YEAST Protein YSC84 OS=Saccharomyces ce... | 45 | 0.09 | 38.9 | 38 | 60 | GO:0030479; C:actin cortical patch; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD. | 51 | P46108 | 304 | CRK_HUMAN Adapter molecule crk OS=Homo sapien... | 63 | 0.09 | 38.5 | 27 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. | 52 | P24604 | 630 | TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus ... | 57 | 0.11 | 38.5 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 53 | Q6BNP6 | 512 | HSE1_DEBHA Class E vacuolar protein-sorting m... | 111 | 0.12 | 38.5 | 27 | 39 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 54 | A2QW93 | 611 | HSE1_ASPNC Class E vacuolar protein-sorting m... | 78 | 0.14 | 38.1 | 29 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 55 | Q5T2T1 | 576 | MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Ho... | 105 | 0.15 | 38.1 | 26 | 48 | GO:0097025; C:MPP7-DLG1-LIN7 complex; IDA:BHF-UCL.::GO:0005923; C:tight junction; IDA:BHF-UCL. | | | | | | | | | | GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0035591; F:signaling adaptor activity; NAS:BHF-UCL. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; TAS:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.::GO:0070830; P:tight junction assembly; IDA:BHF-UCL. | 56 | O55033 | 380 | NCK2_MOUSE Cytoplasmic protein NCK2 OS=Mus mu... | 70 | 0.15 | 38.1 | 30 | 50 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 57 | Q7T2V3 | 1005 | M3K10_XENLA Mitogen-activated protein kinase ... | 57 | 0.16 | 38.1 | 32 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0071570; P:cement gland development; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB. | 58 | Q0CJU8 | 597 | HSE1_ASPTN Class E vacuolar protein-sorting m... | 78 | 0.17 | 38.1 | 29 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 59 | Q07883 | 217 | GRB2_CHICK Growth factor receptor-bound prote... | 71 | 0.18 | 37 | 28 | 46 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 60 | A6QQZ7 | 576 | MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bo... | 107 | 0.18 | 37.7 | 27 | 45 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 61 | Q5U2Y3 | 576 | MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt... | 68 | 0.2 | 37.7 | 28 | 49 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | |