| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P80667 | 386 | PEX13_YEAST Peroxisomal membrane protein PAS2... | 414 | 3e-65 | 221 | 38 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IGI:SGD. | 2 | Q92266 | 380 | PEX13_PICPA Peroxisomal membrane protein PEX1... | 264 | 5e-58 | 201 | 41 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 3 | O14136 | 288 | PEX13_SCHPO Peroxisomal membrane protein pex1... | 235 | 9e-31 | 124 | 31 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 4 | Q92968 | 403 | PEX13_HUMAN Peroxisomal membrane protein PEX1... | 330 | 4e-23 | 103 | 28 | 45 | GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB.::GO:0001561; P:fatty acid alpha-oxidation; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0060152; P:microtubule-based peroxisome localization; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:UniProtKB.::GO:0001967; P:suckling behavior; ISS:UniProtKB. | 5 | Q9D0K1 | 405 | PEX13_MOUSE Peroxisomal membrane protein PEX1... | 297 | 7e-21 | 97.4 | 27 | 44 | | | | | | | | | | | GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI. | 6 | Q0P5B1 | 403 | PEX13_BOVIN Peroxisomal membrane protein PEX1... | 296 | 2e-20 | 96.3 | 27 | 45 | GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; ISS:UniProtKB. | 7 | Q19951 | 330 | PEX13_CAEEL Probable peroxisomal membrane pro... | 268 | 0.000000000002 | 71.2 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 8 | P46109 | 303 | CRKL_HUMAN Crk-like protein OS=Homo sapiens (... | 74 | 0.0000003 | 55.5 | 35 | 55 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 9 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 74 | 0.0000006 | 54.7 | 34 | 55 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 10 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 68 | 0.0000007 | 54.3 | 35 | 59 | | | | | | | | | | | | | | | | | | | | | | 11 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 131 | 0.0001 | 48.1 | 27 | 41 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q9CX99 | 217 | GRAP_MOUSE GRB2-related adapter protein OS=Mu... | 72 | 0.0004 | 45.4 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 13 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 50 | 0.0006 | 45.4 | 40 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 14 | Q99M51 | 377 | NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu... | 50 | 0.0007 | 45.4 | 40 | 58 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 15 | Q557J6 | 481 | DBNL_DICDI Drebrin-like protein OS=Dictyostel... | 63 | 0.004 | 43.1 | 32 | 51 | GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:dictyBase.::GO:0032037; F:myosin I heavy chain binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0031269; P:pseudopodium assembly; IMP:dictyBase. | 16 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 125 | 0.005 | 42.7 | 26 | 41 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q6P0D7 | 576 | MPP7_DANRE MAGUK p55 subfamily member 7 OS=Da... | 105 | 0.007 | 42.4 | 30 | 50 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 18 | Q13588 | 217 | GRAP_HUMAN GRB2-related adapter protein OS=Ho... | 46 | 0.007 | 41.2 | 41 | 59 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 19 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 46 | 0.009 | 41.2 | 39 | 57 | | | | | | | | | | | | | | | | | | | | | | 20 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 112 | 0.01 | 41.6 | 23 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 21 | P42680 | 631 | TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo... | 57 | 0.011 | 42 | 37 | 53 | GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0010543; P:regulation of platelet activation; IDA:UniProtKB. | 22 | Q7TSG5 | 549 | SH321_MOUSE SH3 domain-containing protein 21 ... | 74 | 0.012 | 41.6 | 36 | 49 | | | | | | | | | | | | | | | | | | | | | | 23 | Q08881 | 620 | ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=... | 114 | 0.014 | 41.6 | 27 | 40 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 24 | Q9WVE9 | 1217 | ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ... | 64 | 0.015 | 41.6 | 39 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD. | 25 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 69 | 0.016 | 40.8 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 26 | Q1E878 | 612 | HSE1_COCIM Class E vacuolar protein-sorting m... | 91 | 0.019 | 41.2 | 30 | 41 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 27 | A4FU49 | 640 | SH321_HUMAN SH3 domain-containing protein 21 ... | 55 | 0.022 | 40.8 | 42 | 56 | | | | | | | | | | | | | | | | | | | | | | 28 | P97814 | 415 | PPIP1_MOUSE Proline-serine-threonine phosphat... | 73 | 0.023 | 40.4 | 34 | 52 | GO:0005826; C:actomyosin contractile ring; IDA:MGI.::GO:0032154; C:cleavage furrow; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IC:MGI. | 29 | Q9XYM0 | 271 | CRK_DROME Adapter molecule Crk OS=Drosophila ... | 103 | 0.028 | 40 | 24 | 45 | | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase. | | | | | | | | | | GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 30 | Q5RC07 | 716 | ES8L2_PONAB Epidermal growth factor receptor ... | 66 | 0.03 | 40.4 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 31 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 66 | 0.032 | 40.4 | 30 | 52 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | |
