rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q95SP2 | 626 | HRD1_DROME E3 ubiquitin-protein ligase HRD1 O... | 436 | 8e-64 | 230 | 33 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB. | 2 | Q5XHH7 | 595 | SYVNB_XENLA E3 ubiquitin-protein ligase synov... | 403 | 6e-62 | 224 | 34 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 3 | Q9DBY1 | 612 | SYVN1_MOUSE E3 ubiquitin-protein ligase synov... | 411 | 7e-62 | 224 | 33 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI. | 4 | Q86TM6 | 617 | SYVN1_HUMAN E3 ubiquitin-protein ligase synov... | 411 | 9e-62 | 224 | 33 | 49 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB. | 5 | Q6NRL6 | 605 | SYVNA_XENLA E3 ubiquitin-protein ligase synov... | 404 | 2e-61 | 223 | 34 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 6 | Q803I8 | 625 | SYVN1_DANRE E3 ubiquitin-protein ligase synov... | 411 | 2e-60 | 220 | 32 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 7 | Q20798 | 610 | HRD1_CAEEL E3 ubiquitin-protein ligase hrd-1 ... | 401 | 1e-52 | 197 | 30 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 8 | A8Y4B2 | 622 | HRD1_CAEBR E3 ubiquitin-protein ligase hrd-1 ... | 398 | 2e-52 | 197 | 30 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 9 | O74757 | 677 | HRD1_SCHPO ERAD-associated E3 ubiquitin-prote... | 409 | 3e-51 | 194 | 31 | 47 | GO:0005938; C:cell cortex; IDA:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:PomBase.::GO:0010620; P:negative regulation of transcription by transcription factor catabolism; IMP:PomBase. | 10 | Q08109 | 551 | HRD1_YEAST ERAD-associated E3 ubiquitin-prote... | 420 | 1e-21 | 103 | 24 | 45 | GO:0000839; C:Hrd1p ubiquitin ligase ERAD-L complex; IDA:SGD.::GO:0000838; C:Hrd1p ubiquitin ligase ERAD-M complex; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD. | 11 | Q75CC8 | 575 | HRD1_ASHGO ERAD-associated E3 ubiquitin-prote... | 405 | 2e-20 | 99.8 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q8VYC8 | 578 | RIN2_ARATH E3 ubiquitin protein ligase RIN2 O... | 410 | 2e-18 | 93.2 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0034052; P:positive regulation of plant-type hypersensitive response; IGI:TAIR. | 13 | Q9R049 | 643 | AMFR_MOUSE E3 ubiquitin-protein ligase AMFR O... | 198 | 0.0000000000001 | 78.2 | 30 | 45 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 14 | Q9UKV5 | 643 | AMFR2_HUMAN E3 ubiquitin-protein ligase AMFR ... | 198 | 0.0000000000003 | 77 | 30 | 45 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 15 | Q8W4Q5 | 577 | RIN3_ARATH E3 ubiquitin protein ligase RIN3 O... | 418 | 0.000000000001 | 74.7 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0034052; P:positive regulation of plant-type hypersensitive response; IGI:TAIR. | 16 | P30631 | 161 | YOUD_CAEEL Uncharacterized RING finger protei... | 29 | 0.00003 | 48.5 | 59 | 69 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 17 | Q9SYU4 | 381 | PEX10_ARATH Peroxisome biogenesis factor 10 O... | 67 | 0.00004 | 50.4 | 34 | 46 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010381; P:attachment of peroxisome to chloroplast; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0009853; P:photorespiration; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IMP:TAIR. | 18 | A8WWR3 | 578 | HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-l... | 148 | 0.00006 | 50.1 | 26 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043526; P:neuroprotection; ISS:UniProtKB. | 19 | P90859 | 564 | HRDL1_CAEEL E3 ubiquitin-protein ligase hrd-l... | 148 | 0.0001 | 48.9 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043526; P:neuroprotection; IMP:UniProtKB. | 20 | Q7TPV2 | 1204 | DZIP3_MOUSE E3 ubiquitin-protein ligase DZIP3... | 80 | 0.0002 | 48.9 | 33 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | Q9BV68 | 326 | RN126_HUMAN RING finger protein 126 OS=Homo s... | 67 | 0.0002 | 47.8 | 37 | 51 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 22 | Q91YL2 | 313 | RN126_MOUSE RING finger protein 126 OS=Mus mu... | 67 | 0.0002 | 47.8 | 37 | 51 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 23 | Q09251 | 409 | RN121_CAEEL RING finger protein 121 OS=Caenor... | 132 | 0.0003 | 47.8 | 27 | 43 | GO:0000139; C:Golgi membrane; IDA:WormBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:WormBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:WormBase.::GO:0030433; P:ER-associated protein catabolic process; IMP:WormBase. | 24 | Q7T037 | 757 | RF12B_XENLA E3 ubiquitin-protein ligase RNF12... | 35 | 0.0005 | 47.4 | 46 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 25 | Q7KRW1 | 809 | TRC8_DROME Protein TRC8 homolog OS=Drosophila... | 102 | 0.0008 | 46.6 | 27 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0007418; P:ventral midline development; IMP:UniProtKB. | 26 | Q0II22 | 313 | RN126_BOVIN RING finger protein 126 OS=Bos ta... | 67 | 0.0008 | 45.8 | 36 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 27 | Q9NVW2 | 624 | RNF12_HUMAN E3 ubiquitin-protein ligase RLIM ... | 35 | 0.0009 | 46.6 | 46 | 54 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; NAS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 28 | Q86Y13 | 1208 | DZIP3_HUMAN E3 ubiquitin-protein ligase DZIP3... | 77 | 0.0009 | 46.6 | 32 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019902; F:phosphatase binding; IDA:UniProtKB.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 29 | Q07G42 | 639 | RNF12_XENTR E3 ubiquitin-protein ligase RNF12... | 35 | 0.0009 | 46.6 | 46 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 30 | Q9WTV7 | 600 | RNF12_MOUSE E3 ubiquitin-protein ligase RLIM ... | 35 | 0.001 | 46.2 | 46 | 54 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 31 | Q9ULK6 | 438 | RN150_HUMAN RING finger protein 150 OS=Homo s... | 147 | 0.001 | 45.8 | 28 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |