| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12514 | 560 | NOT5_YEAST General negative regulator of tran... | 591 | 2e-69 | 238 | 32 | 49 | GO:0030015; C:CCR4-NOT core complex; IPI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IMP:SGD.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IDA:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0016567; P:protein ubiquitination; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:SGD. | 2 | O13870 | 640 | NOT3_SCHPO General negative regulator of tran... | 132 | 6e-17 | 87.8 | 33 | 54 | GO:0030015; C:CCR4-NOT core complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; ISS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | O75175 | 753 | CNOT3_HUMAN CCR4-NOT transcription complex su... | 127 | 0.00000000001 | 70.9 | 35 | 50 | GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q8K0V4 | 751 | CNOT3_MOUSE CCR4-NOT transcription complex su... | 127 | 0.00000000001 | 70.9 | 35 | 50 | GO:0000932; C:cytoplasmic mRNA processing body; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | P06102 | 836 | NOT3_YEAST General negative regulator of tran... | 283 | 4e-36 | 147 | 36 | 59 | GO:0030015; C:CCR4-NOT core complex; IPI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IDA:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0016567; P:protein ubiquitination; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q52JK6 | 603 | VIP2_NICBE Probable NOT transcription complex... | 44 | 0.0003 | 47.4 | 52 | 64 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0015074; P:DNA integration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q94547 | 585 | RGA_DROME Regulator of gene activity OS=Droso... | 79 | 0.0006 | 46.2 | 37 | 52 | GO:0030014; C:CCR4-NOT complex; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB. | 8 | Q9FPW4 | 614 | VIP2_ARATH Probable NOT transcription complex... | 46 | 0.039 | 40.4 | 41 | 61 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0015074; P:DNA integration; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q8C5L3 | 540 | CNOT2_MOUSE CCR4-NOT transcription complex su... | 111 | 0.052 | 40 | 27 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q9NZN8 | 540 | CNOT2_HUMAN CCR4-NOT transcription complex su... | 111 | 0.057 | 39.7 | 27 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0001104; F:RNA polymerase II transcription cofactor activity; TAS:UniProtKB. | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome. | 11 | P87240 | 306 | NOT2_SCHPO General negative regulator of tran... | 78 | 0.16 | 38.1 | 31 | 50 | GO:0030015; C:CCR4-NOT core complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; ISS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0006354; P:transcription elongation, DNA-dependent; IC:PomBase. | 12 | Q21313 | 3672 | EPI1_CAEEL Laminin-like protein epi-1 OS=Caen... | 332 | 1.4 | 35.4 | 21 | 41 | GO:0005604; C:basement membrane; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:InterPro. | 13 | Q7TT49 | 1713 | MRCKB_RAT Serine/threonine-protein kinase MRC... | 97 | 2.1 | 35 | 31 | 53 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017048; F:Rho GTPase binding; IDA:RGD.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 14 | B8J1Q5 | 260 | GCH4_DESDA GTP cyclohydrolase folE2 OS=Desulf... | 69 | 2.4 | 34.3 | 35 | 51 | | | | | | | | | | | GO:0003934; F:GTP cyclohydrolase I activity; IEA:EC. | | | | | | | | | | | 15 | Q7TT50 | 1713 | MRCKB_MOUSE Serine/threonine-protein kinase M... | 97 | 2.9 | 34.7 | 31 | 52 | GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 16 | Q7T005 | 1183 | RFIP3_DANRE Rab11 family-interacting protein ... | 187 | 3.3 | 34.3 | 27 | 49 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030306; F:ADP-ribosylation factor binding; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0032456; P:endocytic recycling; ISS:UniProtKB. | 17 | Q9Y5S2 | 1711 | MRCKB_HUMAN Serine/threonine-protein kinase M... | 97 | 3.5 | 34.3 | 31 | 53 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 18 | Q9N4M4 | 8545 | ANC1_CAEEL Nuclear anchorage protein 1 OS=Cae... | 185 | 4 | 34.3 | 27 | 45 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0051179; P:localization; TAS:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase. | 19 | Q93833 | 412 | CHE13_CAEEL Intraflagellar transport protein ... | 153 | 4.1 | 33.9 | 26 | 46 | GO:0035085; C:cilium axoneme; IDA:WormBase.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0031513; C:nonmotile primary cilium; IDA:WormBase. | | | | | | | | | | GO:0005198; F:structural molecule activity; IMP:WormBase. | | | | | | | | | | GO:0007635; P:chemosensory behavior; IMP:WormBase.::GO:0042384; P:cilium assembly; IMP:WormBase.::GO:0008104; P:protein localization; IMP:WormBase. | 20 | Q09472 | 2414 | EP300_HUMAN Histone acetyltransferase p300 OS... | 91 | 4.8 | 33.9 | 25 | 49 | GO:0005813; C:centrosome; IDA:HPA. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043923; P:positive regulation by host of viral transcription; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q5V1F7 | 508 | RFCL_HALMA Replication factor C large subunit... | 109 | 6 | 33.1 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 22 | Q91YL3 | 548 | UCKL1_MOUSE Uridine-cytidine kinase-like 1 OS... | 73 | 7.6 | 33.1 | 36 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | | 23 | P45481 | 2441 | CBP_MOUSE CREB-binding protein OS=Mus musculu... | 103 | 8.7 | 33.1 | 26 | 44 | GO:0000940; C:condensed chromosome outer kinetochore; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0043426; F:MRF binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030718; P:germ-line stem cell maintenance; IMP:MGI.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
