rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q06409 | 1932 | YL422_YEAST DOCK-like protein YLR422W OS=Sacc... | 1729 | 0 | 692 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | | 2 | Q8CIQ7 | 2027 | DOCK3_MOUSE Dedicator of cytokinesis protein ... | 692 | 2e-39 | 165 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 3 | Q8IZD9 | 2030 | DOCK3_HUMAN Dedicator of cytokinesis protein ... | 693 | 3e-39 | 164 | 24 | 44 | GO:0005737; C:cytoplasm; IDA:HPA. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | Q8N1I0 | 1966 | DOCK4_HUMAN Dedicator of cytokinesis protein ... | 621 | 9e-32 | 140 | 23 | 43 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0032420; C:stereocilium; ISS:HGNC. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; IPI:HGNC.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0048365; F:Rac GTPase binding; IDA:HGNC.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060326; P:cell chemotaxis; IMP:UniProtKB. | 5 | P59764 | 1978 | DOCK4_MOUSE Dedicator of cytokinesis protein ... | 630 | 3e-31 | 138 | 23 | 43 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0032420; C:stereocilium; IDA:HGNC. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060326; P:cell chemotaxis; ISS:UniProtKB. | 6 | B2RY04 | 1868 | DOCK5_MOUSE Dedicator of cytokinesis protein ... | 633 | 4e-30 | 134 | 23 | 42 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | | 7 | Q14185 | 1865 | DOCK1_HUMAN Dedicator of cytokinesis protein ... | 634 | 1e-28 | 129 | 22 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.::GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 8 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 630 | 2e-28 | 129 | 22 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 9 | Q8BUR4 | 1865 | DOCK1_MOUSE Dedicator of cytokinesis protein ... | 639 | 6e-28 | 127 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 10 | Q8C3J5 | 1828 | DOCK2_MOUSE Dedicator of cytokinesis protein ... | 698 | 3e-23 | 112 | 20 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IMP:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0042608; F:T cell receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0046633; P:alpha-beta T cell proliferation; IMP:MGI.::GO:0006935; P:chemotaxis; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0001768; P:establishment of T cell polarity; IMP:MGI.::GO:0001771; P:immunological synapse formation; IMP:MGI.::GO:0001766; P:membrane raft polarization; IMP:MGI.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI. | 11 | Q92608 | 1830 | DOCK2_HUMAN Dedicator of cytokinesis protein ... | 572 | 6e-21 | 104 | 21 | 42 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0042608; F:T cell receptor binding; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 12 | Q5JSL3 | 2073 | DOC11_HUMAN Dedicator of cytokinesis protein ... | 378 | 0.00000002 | 63.5 | 24 | 38 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome. | 13 | A2AF47 | 2073 | DOC11_MOUSE Dedicator of cytokinesis protein ... | 373 | 0.00000003 | 62.8 | 23 | 39 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | | 14 | Q9BZ29 | 2069 | DOCK9_HUMAN Dedicator of cytokinesis protein ... | 368 | 0.00000008 | 61.6 | 24 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome. | 15 | Q8BIK4 | 2055 | DOCK9_MOUSE Dedicator of cytokinesis protein ... | 374 | 0.0000005 | 58.5 | 23 | 39 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 16 | Q96BY6 | 2186 | DOC10_HUMAN Dedicator of cytokinesis protein ... | 315 | 0.00001 | 54.3 | 26 | 42 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 17 | Q8BZN6 | 2150 | DOC10_MOUSE Dedicator of cytokinesis protein ... | 317 | 0.0007 | 48.5 | 24 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 18 | Q8R1A4 | 2130 | DOCK7_MOUSE Dedicator of cytokinesis protein ... | 356 | 0.001 | 47.8 | 21 | 39 | GO:0030424; C:axon; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043473; P:pigmentation; IMP:MGI. | 19 | Q96N67 | 2140 | DOCK7_HUMAN Dedicator of cytokinesis protein ... | 356 | 0.002 | 47 | 21 | 40 | GO:0030424; C:axon; TAS:BHF-UCL.::GO:0045178; C:basal part of cell; TAS:BHF-UCL.::GO:0030426; C:growth cone; TAS:BHF-UCL. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IDA:BHF-UCL.::GO:0007409; P:axonogenesis; IMP:BHF-UCL.::GO:0045200; P:establishment of neuroblast polarity; IMP:BHF-UCL.::GO:0000226; P:microtubule cytoskeleton organization; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL. | 20 | Q63603 | 720 | DOCK9_RAT Dedicator of cytokinesis protein 9 ... | 275 | 0.021 | 43.5 | 23 | 40 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q2SML5 | 150 | RIMP_HAHCH Ribosome maturation factor RimP OS... | 83 | 1.2 | 35.8 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. | 22 | Q619V5 | 385 | GPA5_CAEBR Guanine nucleotide-binding protein... | 65 | 3.4 | 35.8 | 26 | 58 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro. | 23 | P40064 | 1391 | NU157_YEAST Nucleoporin NUP157 OS=Saccharomyc... | 49 | 3.8 | 36.2 | 29 | 55 | GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IDA:SGD. | | | | | | | | | | GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro. | | | | | | | | | | GO:0006406; P:mRNA export from nucleus; TAS:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; TAS:SGD.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:SGD.::GO:0051292; P:nuclear pore complex assembly; IGI:SGD.::GO:0000973; P:posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.::GO:0006611; P:protein export from nucleus; TAS:SGD.::GO:0006610; P:ribosomal protein import into nucleus; TAS:SGD.::GO:0006407; P:rRNA export from nucleus; TAS:SGD.::GO:0006408; P:snRNA export from nucleus; TAS:SGD.::GO:0006608; P:snRNP protein import into nucleus; TAS:SGD.::GO:0006409; P:tRNA export from nucleus; TAS:SGD. | 24 | C6DA76 | 378 | PDXB_PECCP Erythronate-4-phosphate dehydrogen... | 133 | 5.6 | 35 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW. | 25 | O03685 | 831 | RPOP_GELSP Probable DNA-directed RNA polymera... | 223 | 6.3 | 35.4 | 25 | 42 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | |