| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53170 | 491 | PKP2_YEAST Pyruvate dehydrogenase kinase 2, m... | 452 | 1e-107 | 335 | 41 | 62 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD. | 2 | O14874 | 412 | BCKD_HUMAN [3-methyl-2-oxobutanoate dehydroge... | 377 | 9e-34 | 135 | 27 | 44 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 3 | Q2KJG8 | 412 | BCKD_BOVIN [3-methyl-2-oxobutanoate dehydroge... | 381 | 9e-34 | 135 | 27 | 45 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 4 | O55028 | 412 | BCKD_MOUSE [3-methyl-2-oxobutanoate dehydroge... | 377 | 2e-33 | 134 | 27 | 45 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 5 | Q00972 | 412 | BCKD_RAT [3-methyl-2-oxobutanoate dehydrogena... | 377 | 3e-33 | 134 | 27 | 44 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; IDA:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IMP:RGD.::GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; IDA:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 6 | Q1KMR4 | 412 | PDK4_RHIFE [Pyruvate dehydrogenase [lipoamide... | 414 | 4e-24 | 107 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 7 | P91622 | 413 | PDK_DROME [Pyruvate dehydrogenase [lipoamide]... | 408 | 5e-23 | 104 | 23 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 8 | O88345 | 412 | PDK4_SPETR [Pyruvate dehydrogenase [lipoamide... | 411 | 5e-23 | 104 | 22 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 9 | Q16654 | 411 | PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide... | 413 | 2e-22 | 102 | 22 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 10 | O70571 | 412 | PDK4_MOUSE [Pyruvate dehydrogenase [lipoamide... | 414 | 5e-22 | 101 | 23 | 43 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:MGI.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:MGI.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 11 | Q64536 | 407 | PDK2_RAT [Pyruvate dehydrogenase [lipoamide]]... | 413 | 1e-21 | 100 | 24 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 12 | Q9JK42 | 407 | PDK2_MOUSE [Pyruvate dehydrogenase [lipoamide... | 413 | 2e-21 | 99.8 | 24 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 13 | Q15119 | 407 | PDK2_HUMAN [Pyruvate dehydrogenase [lipoamide... | 410 | 3e-21 | 99 | 24 | 43 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 14 | O54937 | 412 | PDK4_RAT [Pyruvate dehydrogenase [lipoamide]]... | 414 | 2e-20 | 96.7 | 22 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 15 | Q8BFP9 | 434 | PDK1_MOUSE [Pyruvate dehydrogenase [lipoamide... | 410 | 1e-19 | 94.7 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 16 | O02623 | 399 | PDK_ASCSU [Pyruvate dehydrogenase [lipoamide]... | 413 | 2e-19 | 93.6 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 17 | Q63065 | 434 | PDK1_RAT [Pyruvate dehydrogenase [lipoamide]]... | 410 | 7e-19 | 92.4 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IMP:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 18 | Q922H2 | 415 | PDK3_MOUSE [Pyruvate dehydrogenase [lipoamide... | 422 | 1e-18 | 91.7 | 23 | 40 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 19 | Q15120 | 406 | PDK3_HUMAN [Pyruvate dehydrogenase [lipoamide... | 420 | 3e-18 | 90.5 | 24 | 41 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 20 | Q9P6P9 | 425 | PDK_SCHPO [Pyruvate dehydrogenase [lipoamide]... | 43 | 0.002 | 43.9 | 51 | 67 | GO:0005967; C:mitochondrial pyruvate dehydrogenase complex; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; ISS:PomBase.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; ISS:PomBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 21 | Q15118 | 436 | PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide... | 411 | 9e-18 | 89 | 23 | 43 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 22 | Q02332 | 401 | PDHK2_CAEEL Probable [pyruvate dehydrogenase ... | 418 | 0.000000000000008 | 79.7 | 22 | 41 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 23 | P40530 | 394 | PDK_YEAST [Pyruvate dehydrogenase [lipoamide]... | 400 | 0.000000000006 | 70.9 | 22 | 40 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD. | 24 | O82436 | 740 | ETR1_CUCMN Ethylene receptor 1 OS=reticulatus... | 250 | 0.27 | 37.7 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009873; P:ethylene mediated signaling pathway; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 25 | Q2G9U3 | 346 | PYRC_NOVAD Dihydroorotase OS=Novosphingobium ... | 109 | 0.81 | 35.8 | 27 | 44 | | | | | | | | | | | GO:0004151; F:dihydroorotase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019856; P:pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 26 | Q9SSY6 | 740 | ETR1_CUCSA Ethylene receptor 1 OS=Cucumis sat... | 250 | 3.4 | 33.9 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009873; P:ethylene mediated signaling pathway; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 27 | Q492W0 | 295 | ISPE_BLOPB 4-diphosphocytidyl-2-C-methyl-D-er... | 107 | 4.7 | 33.1 | 25 | 50 | | | | | | | | | | | GO:0050515; F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016114; P:terpenoid biosynthetic process; IEA:InterPro. | 28 | Q61245 | 1804 | COBA1_MOUSE Collagen alpha-1(XI) chain OS=Mus... | 71 | 4.9 | 33.5 | 34 | 49 | | | | | | | | | | | GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro. | | | | | | | | | | GO:0001502; P:cartilage condensation; IMP:MGI.::GO:0002063; P:chondrocyte development; IMP:MGI.::GO:0030199; P:collagen fibril organization; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0006029; P:proteoglycan metabolic process; IMP:MGI.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI. |
