rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | O35180 | 347 | SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ... | 83 | 0.000002 | 53.1 | 37 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 92 | P38753 | 452 | HSE1_YEAST Class E vacuolar protein-sorting m... | 53 | 0.000002 | 53.1 | 47 | 58 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD. | 93 | Q99963 | 347 | SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu... | 52 | 0.000002 | 52.8 | 46 | 67 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 94 | O93436 | 468 | STAM2_CHICK Signal transducing adapter molecu... | 50 | 0.000002 | 53.1 | 46 | 66 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 95 | A4FU49 | 640 | SH321_HUMAN SH3 domain-containing protein 21 ... | 91 | 0.000002 | 53.1 | 29 | 46 | | | | | | | | | | | | | | | | | | | | | | 96 | Q7ZYG4 | 214 | OSTF1_XENLA Osteoclast-stimulating factor 1 O... | 50 | 0.000002 | 51.6 | 46 | 66 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 97 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 89 | 0.000003 | 52.4 | 39 | 53 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 98 | Q91X43 | 789 | SH319_MOUSE SH3 domain-containing protein 19 ... | 60 | 0.025 | 40.4 | 33 | 57 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 99 | O43295 | 1099 | SRGP3_HUMAN SLIT-ROBO Rho GTPase-activating p... | 53 | 0.000003 | 53.1 | 40 | 64 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 100 | Q13588 | 217 | GRAP_HUMAN GRB2-related adapter protein OS=Ho... | 56 | 0.0003 | 45.4 | 34 | 55 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 101 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 96 | 0.000003 | 52.4 | 34 | 53 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 102 | Q99M51 | 377 | NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu... | 52 | 0.058 | 38.9 | 35 | 54 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 103 | Q62421 | 347 | SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo... | 52 | 0.000004 | 52.4 | 46 | 65 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 104 | Q9QY53 | 687 | NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M... | 66 | 0.000004 | 52.8 | 42 | 58 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB. | 105 | Q6YKA8 | 211 | DRK_DROSI Protein E(sev)2B OS=Drosophila simu... | 56 | 0.033 | 39.3 | 30 | 55 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 106 | Q08012 | 211 | DRK_DROME Protein enhancer of sevenless 2B OS... | 56 | 0.033 | 39.3 | 30 | 55 | GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase. | 107 | O88811 | 523 | STAM2_MOUSE Signal transducing adapter molecu... | 78 | 0.000004 | 52.4 | 36 | 54 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 108 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 52 | 0.066 | 38.9 | 35 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 109 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 56 | 0.0006 | 44.3 | 34 | 54 | | | | | | | | | | | | | | | | | | | | | | 110 | Q812A2 | 1099 | SRGP3_MOUSE SLIT-ROBO Rho GTPase-activating p... | 53 | 0.000005 | 52.8 | 40 | 64 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 111 | Q5I0D6 | 502 | NOSTN_RAT Nostrin OS=Rattus norvegicus (Rat).... | 51 | 0.000005 | 52.4 | 47 | 63 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 112 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 75 | 0.000005 | 51.6 | 40 | 56 | | | | | | | | | | | | | | | | | | | | | | 113 | P46109 | 303 | CRKL_HUMAN Crk-like protein OS=Homo sapiens (... | 51 | 0.000006 | 51.6 | 47 | 65 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 114 | Q07883 | 217 | GRB2_CHICK Growth factor receptor-bound prote... | 56 | 0.0003 | 45.4 | 36 | 57 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 115 | P14317 | 486 | HCLS1_HUMAN Hematopoietic lineage cell-specif... | 55 | 0.000006 | 52 | 44 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB. | 116 | Q7TSG5 | 549 | SH321_MOUSE SH3 domain-containing protein 21 ... | 91 | 0.000006 | 52 | 30 | 46 | | | | | | | | | | | | | | | | | | | | | | 117 | P34109 | 1109 | MYOD_DICDI Myosin ID heavy chain OS=Dictyoste... | 92 | 0.000008 | 52 | 35 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 118 | A7E3N2 | 527 | NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu... | 72 | 0.058 | 39.3 | 32 | 50 | GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD. | 119 | Q99469 | 402 | STAC_HUMAN SH3 and cysteine-rich domain-conta... | 54 | 0.00001 | 50.8 | 39 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 120 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 57 | 0.00001 | 51.6 | 32 | 61 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 121 | Q2KJB5 | 505 | NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G... | 51 | 0.00001 | 50.8 | 47 | 59 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |