rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | C4QVD6 | 273 | SHO1_PICPG High osmolarity signaling protein ... | 56 | 0.77 | 35.4 | 38 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 512 | Q95UN8 | 1161 | M3KSL_DROME Mitogen-activated protein kinase ... | 53 | 0.78 | 35.8 | 28 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0071361; P:cellular response to ethanol; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048804; P:imaginal disc-derived female genitalia morphogenesis; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 513 | A1C4A5 | 1253 | MYO1_ASPCL Myosin-1 OS=3887 / NRRL 1). GN=myo... | 52 | 0.8 | 35.8 | 35 | 50 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 514 | P42679 | 507 | MATK_HUMAN Megakaryocyte-associated tyrosine-... | 71 | 0.82 | 35.4 | 32 | 52 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc. | 515 | Q62415 | 1087 | ASPP1_MOUSE Apoptosis-stimulating of p53 prot... | 53 | 0.83 | 35.8 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 516 | B2RY04 | 1868 | DOCK5_MOUSE Dedicator of cytokinesis protein ... | 64 | 0.86 | 35.8 | 28 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | | 517 | Q66L42 | 940 | M3K10_MOUSE Mitogen-activated protein kinase ... | 67 | 0.87 | 35.8 | 28 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 518 | A1A4S6 | 786 | RHG10_HUMAN Rho GTPase-activating protein 10 ... | 103 | 0.88 | 35.8 | 27 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 519 | D1ZRK4 | 320 | SHO1_SORMK High osmolarity signaling protein ... | 65 | 0.89 | 35 | 29 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 520 | Q28GP7 | 549 | SNX33_XENTR Sorting nexin-33 OS=Xenopus tropi... | 60 | 0.9 | 35.4 | 37 | 63 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 521 | A7F1F4 | 317 | SHO1_SCLS1 High osmolarity signaling protein ... | 65 | 0.91 | 35 | 28 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 522 | Q02779 | 954 | M3K10_HUMAN Mitogen-activated protein kinase ... | 68 | 1 | 35.4 | 28 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB. | 523 | Q9QYH1 | 441 | MPP4_RAT MAGUK p55 subfamily member 4 OS=Ratt... | 42 | 1 | 35.4 | 36 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005102; F:receptor binding; IPI:UniProtKB. | | | | | | | | | | | 524 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 56 | 1.1 | 35.4 | 32 | 54 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 525 | Q5I1X5 | 824 | IASPP_MOUSE RelA-associated inhibitor OS=Mus ... | 54 | 1.2 | 35.4 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:MGI.::GO:0031076; P:embryonic camera-type eye development; IMP:MGI.::GO:0042633; P:hair cycle; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0048871; P:multicellular organismal homeostasis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003229; P:ventricular cardiac muscle tissue development; IMP:MGI. | 526 | Q07840 | 426 | EM13_ECHMU Antigen EM13 OS=Echinococcus multi... | 46 | 1.3 | 35 | 35 | 54 | | | | | | | | | | | | | | | | | | | | | | 527 | O76041 | 1014 | NEBL_HUMAN Nebulette OS=Homo sapiens (Human).... | 55 | 1.3 | 35 | 31 | 55 | GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB. | | | | | | | | | | GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB. | 528 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 46 | 1.3 | 35 | 35 | 54 | | | | | | | | | | | | | | | | | | | | | | 529 | O77506 | 263 | LASP1_RABIT LIM and SH3 domain protein 1 OS=O... | 80 | 1.3 | 34.7 | 30 | 48 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 530 | Q75JD4 | 533 | Y1676_DICDI SH3 and FCH domain-containing pro... | 55 | 1.4 | 35 | 35 | 60 | | | | | | | | | | | | | | | | | | | | | | 531 | Q8WUF5 | 828 | IASPP_HUMAN RelA-associated inhibitor OS=Homo... | 54 | 1.4 | 35 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 532 | B3DLB3 | 433 | ANM2_XENTR Protein arginine N-methyltransfera... | 28 | 1.5 | 34.7 | 43 | 64 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB. | 533 | Q08DP6 | 785 | RHG10_BOVIN Rho GTPase-activating protein 10 ... | 56 | 1.5 | 35 | 32 | 54 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 534 | Q1DLP2 | 1251 | MYO1_COCIM Myosin-1 OS=Coccidioides immitis (... | 57 | 1.6 | 35 | 32 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 535 | C5MB30 | 340 | SHO1_CANTT High osmolarity signaling protein ... | 59 | 1.6 | 34.7 | 32 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 536 | Q9JJS5 | 961 | SH3B4_RAT SH3 domain-binding protein 4 OS=Rat... | 93 | 1.6 | 34.7 | 30 | 46 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 537 | Q921I6 | 962 | SH3B4_MOUSE SH3 domain-binding protein 4 OS=M... | 93 | 1.6 | 34.7 | 30 | 46 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 538 | O42854 | 1611 | YFHH_SCHPO SH3 domain-containing protein C23A... | 60 | 1.7 | 35 | 33 | 50 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0017024; F:myosin I binding; ISS:PomBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 539 | O89032 | 1124 | SPD2A_MOUSE SH3 and PX domain-containing prot... | 54 | 1.7 | 34.7 | 26 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 540 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 54 | 1.8 | 34.7 | 26 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 541 | Q96JP2 | 1530 | MY15B_HUMAN Putative unconventional myosin-XV... | 59 | 1.9 | 34.7 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | |