rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
481 | Q2HWF0 | 605 | FBP1L_RAT Formin-binding protein 1-like OS=Ra... | 53 | 0.39 | 36.6 | 36 | 55 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 482 | Q6GUF4 | 550 | FBP1L_XENTR Formin-binding protein 1-like OS=... | 53 | 0.39 | 36.6 | 36 | 57 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 483 | Q9XVN3 | 769 | IASPP_CAEEL Apoptotic enhancer 1 protein OS=C... | 53 | 0.4 | 36.6 | 30 | 51 | GO:0005634; C:nucleus; ISS:WormBase. | | | | | | | | | | GO:0002039; F:p53 binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase. | 484 | D4DA58 | 285 | SHO1_TRIVH High osmolarity signaling protein ... | 67 | 0.42 | 36.2 | 27 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 485 | D4ARB8 | 285 | SHO1_ARTBC High osmolarity signaling protein ... | 67 | 0.42 | 36.2 | 27 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 486 | Q62077 | 1302 | PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 67 | 0.42 | 37 | 34 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI. | 487 | P10686 | 1290 | PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 67 | 0.42 | 36.6 | 34 | 49 | GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD. | 488 | Q92608 | 1830 | DOCK2_HUMAN Dedicator of cytokinesis protein ... | 58 | 0.43 | 37 | 29 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0042608; F:T cell receptor binding; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 489 | Q96KQ4 | 1090 | ASPP1_HUMAN Apoptosis-stimulating of p53 prot... | 55 | 0.43 | 36.6 | 31 | 53 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB. | 490 | Q91WL0 | 600 | ES8L3_MOUSE Epidermal growth factor receptor ... | 67 | 0.46 | 36.6 | 27 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 491 | Q09014 | 390 | NCF1_MOUSE Neutrophil cytosol factor 1 OS=Mus... | 66 | 0.46 | 36.2 | 23 | 48 | GO:0005829; C:cytosol; TAS:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006968; P:cellular defense response; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0006691; P:leukotriene metabolic process; IMP:MGI.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:MGI.::GO:0070947; P:neutrophil mediated killing of fungus; IMP:MGI.::GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IMP:MGI.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; IMP:MGI.::GO:0001878; P:response to yeast; IMP:MGI.::GO:0042554; P:superoxide anion generation; IMP:MGI. | 492 | C5FH98 | 284 | SHO1_ARTOC High osmolarity signaling protein ... | 67 | 0.46 | 36.2 | 27 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 493 | Q9PAP4 | 302 | SCPA_XYLFA Segregation and condensation prote... | 95 | 0.47 | 36.2 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 494 | P42686 | 505 | SRK1_SPOLA Tyrosine-protein kinase isoform SR... | 51 | 0.52 | 36.2 | 39 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 495 | P51451 | 505 | BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo... | 95 | 0.54 | 36.2 | 28 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB. | 496 | C0S7Q7 | 309 | SHO1_PARBP High osmolarity signaling protein ... | 101 | 0.57 | 35.8 | 27 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 497 | P34092 | 1111 | MYOB_DICDI Myosin IB heavy chain OS=Dictyoste... | 72 | 0.57 | 36.2 | 33 | 50 | GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0032031; F:myosin I head/neck binding; IDA:dictyBase. | | | | | | | | | | GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051707; P:response to other organism; TAS:dictyBase. | 498 | P42690 | 506 | SRK4_SPOLA Tyrosine-protein kinase isoform SR... | 51 | 0.58 | 36.2 | 39 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 499 | P15891 | 592 | ABP1_YEAST Actin-binding protein OS=Saccharom... | 56 | 0.58 | 36.2 | 38 | 54 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD. | 500 | C4JLG3 | 283 | SHO1_UNCRE High osmolarity signaling protein ... | 71 | 0.61 | 35.8 | 27 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 501 | Q8BUR4 | 1865 | DOCK1_MOUSE Dedicator of cytokinesis protein ... | 63 | 0.62 | 36.2 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 502 | Q14185 | 1865 | DOCK1_HUMAN Dedicator of cytokinesis protein ... | 63 | 0.62 | 36.2 | 30 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.::GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 503 | Q5U3Q6 | 542 | CIP4_DANRE Cdc42-interacting protein 4 homolo... | 56 | 0.64 | 35.8 | 34 | 54 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 504 | C1GJ63 | 302 | SHO1_PARBD High osmolarity signaling protein ... | 101 | 0.64 | 35.8 | 27 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 505 | P38479 | 617 | ABP1_SACEX Actin-binding protein OS=Saccharom... | 56 | 0.66 | 35.8 | 38 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 506 | A8N2Y6 | 1277 | MYO1_COPC7 Myosin-1 OS=9003) (Inky cap fungus... | 53 | 0.69 | 36.2 | 32 | 58 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 507 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 64 | 0.73 | 36.2 | 28 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 508 | Q6FTC4 | 353 | SHO1_CANGA High osmolarity signaling protein ... | 56 | 0.73 | 35.4 | 34 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 509 | Q87BI4 | 302 | SCPA_XYLFT Segregation and condensation prote... | 102 | 0.74 | 35.4 | 30 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 510 | P42685 | 505 | FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo... | 89 | 0.77 | 35.8 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 511 | C4QVD6 | 273 | SHO1_PICPG High osmolarity signaling protein ... | 56 | 0.77 | 35.4 | 38 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. |