| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P43069 | 1333 | CDC25_CANAL Cell division control protein 25 ... | 64 | 0.00005 | 49.3 | 45 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:CGD. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IMP:CGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071333; P:cellular response to glucose stimulus; IMP:CGD.::GO:0030447; P:filamentous growth; IMP:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IGI:CGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 152 | Q09822 | 927 | CDC15_SCHPO Cell division control protein 15 ... | 59 | 0.00005 | 49.3 | 34 | 59 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032178; C:medial membrane band; IDA:PomBase. | | | | | | | | | | GO:0043495; F:protein anchor; TAS:PomBase. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0061166; P:establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051125; P:regulation of actin nucleation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 153 | P15498 | 845 | VAV_HUMAN Proto-oncogene vav OS=Homo sapiens ... | 73 | 5.5 | 33.1 | 34 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 154 | O75886 | 525 | STAM2_HUMAN Signal transducing adapter molecu... | 50 | 0.00005 | 48.9 | 42 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 155 | Q3UUV5 | 355 | SKAP1_MOUSE Src kinase-associated phosphoprot... | 49 | 0.00006 | 48.5 | 43 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 156 | P41239 | 450 | CSK_CHICK Tyrosine-protein kinase CSK OS=Gall... | 57 | 0.00006 | 48.9 | 47 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 157 | Q5XHY7 | 523 | STAM2_RAT Signal transducing adapter molecule... | 50 | 0.00006 | 48.9 | 40 | 66 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 158 | P41241 | 450 | CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ... | 57 | 0.00006 | 48.5 | 47 | 61 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC. | 159 | Q0VBZ0 | 450 | CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ... | 57 | 0.00006 | 48.5 | 47 | 61 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 160 | Q66II3 | 229 | GRB2_XENTR Growth factor receptor-bound prote... | 56 | 0.0004 | 45.1 | 34 | 57 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 161 | P41240 | 450 | CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo... | 57 | 0.00006 | 48.5 | 47 | 61 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005886; C:plasma membrane; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 162 | Q8VCZ6 | 750 | SGSM3_MOUSE Small G protein signaling modulat... | 67 | 0.00006 | 48.9 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 163 | P32577 | 450 | CSK_RAT Tyrosine-protein kinase CSK OS=Rattus... | 57 | 0.00006 | 48.5 | 47 | 61 | GO:0045121; C:membrane raft; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0034332; P:adherens junction organization; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IDA:RGD.::GO:0045779; P:negative regulation of bone resorption; IDA:RGD.::GO:0008285; P:negative regulation of cell proliferation; IDA:RGD.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IDA:RGD.::GO:0033673; P:negative regulation of kinase activity; IDA:RGD.::GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IDA:RGD.::GO:0050765; P:negative regulation of phagocytosis; IDA:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0060368; P:regulation of Fc receptor mediated stimulatory signaling pathway; IDA:RGD. | 164 | Q6P6R7 | 749 | SGSM3_RAT Small G protein signaling modulator... | 67 | 0.00007 | 48.9 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 165 | Q6CVA8 | 508 | HSE1_KLULA Class E vacuolar protein-sorting m... | 50 | 0.00007 | 48.5 | 44 | 60 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 166 | Q5A895 | 498 | HSE1_CANAL Class E vacuolar protein-sorting m... | 88 | 0.00007 | 48.5 | 34 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 167 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 99 | 0.00007 | 48.1 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 168 | A8PWF6 | 1322 | MYO1_MALGO Myosin-1 OS=(Dandruff-associated f... | 53 | 0.00007 | 48.9 | 36 | 64 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 169 | Q9R1Z8 | 733 | VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ... | 117 | 0.026 | 40.4 | 30 | 48 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:MGI. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI. | 170 | E9Q634 | 1107 | MYO1E_MOUSE Unconventional myosin-Ie OS=Mus m... | 80 | 0.00008 | 48.9 | 38 | 50 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0003094; P:glomerular filtration; IMP:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0035166; P:post-embryonic hemopoiesis; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI. | 171 | Q96HU1 | 749 | SGSM3_HUMAN Small G protein signaling modulat... | 67 | 0.00008 | 48.5 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB. | 172 | Q63356 | 1107 | MYO1E_RAT Unconventional myosin-Ie OS=Rattus ... | 53 | 0.00008 | 48.5 | 43 | 58 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0003094; P:glomerular filtration; ISS:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB. | 173 | P13115 | 532 | SRC1_XENLA Tyrosine-protein kinase Src-1 OS=X... | 88 | 0.00008 | 48.5 | 36 | 52 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 174 | P54100 | 843 | VAV_RAT Proto-oncogene vav OS=Rattus norvegic... | 73 | 0.00009 | 48.5 | 40 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0048468; P:cell development; TAS:RGD.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 175 | Q91Z69 | 1062 | SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating p... | 53 | 0.00009 | 48.5 | 36 | 62 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI. | | | | | | | | | | GO:0016477; P:cell migration; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 176 | Q86WV1 | 359 | SKAP1_HUMAN Src kinase-associated phosphoprot... | 56 | 0.00009 | 47.8 | 38 | 55 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IC:UniProtKB. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB. | 177 | O77775 | 527 | NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos... | 72 | 0.082 | 38.9 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 178 | Q6GPJ9 | 229 | GRB2B_XENLA Growth factor receptor-bound prot... | 56 | 0.0002 | 46.2 | 38 | 57 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 179 | Q4V7G1 | 354 | SKAP1_RAT Src kinase-associated phosphoprotei... | 49 | 0.00009 | 47.8 | 41 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042169; F:SH2 domain binding; IPI:RGD. | | | | | | | | | | | 180 | Q62419 | 368 | SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo... | 53 | 0.0001 | 47.8 | 40 | 68 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 181 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 98 | 0.0001 | 47.4 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. |
