Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Coccidiodis immitis RMSCC 3703
Locus:
CISG_00060
Length:
148
Number of sequences:
10463
Description:
conserved hypothetical protein
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91O55043    646   ARHG7_RAT Rho guanine nucleotide exchange fac...550.00004     45.8     38     56GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD.
92A1CEK6    599   HSE1_ASPCL Class E vacuolar protein-sorting m...550.00004     45.8     36     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
93Q4WHP5    584   HSE1_ASPFU Class E vacuolar protein-sorting m...550.00004     45.8     36     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
94A1DFN5    603   HSE1_NEOFI Class E vacuolar protein-sorting m...550.00004     45.4     36     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
95Q6YKA8    211   DRK_DROSI Protein E(sev)2B OS=Drosophila simu...620.0002     43.1     34     52GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
96Q08012    211   DRK_DROME Protein enhancer of sevenless 2B OS...620.0002     43.1     34     52GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.
97P25911    512   LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus ...1090.00005     45.4     30     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005128; F:erythropoietin receptor binding; TAS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IPI:MGI.
GO:0001782; P:B cell homeostasis; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0097028; P:dendritic cell differentiation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; IMP:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; IMP:UniProtKB.::GO:0002762; P:negative regulation of myeloid leukocyte differentiation; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; IMP:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0031175; P:neuron projection development; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0002576; P:platelet degranulation; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0050707; P:regulation of cytokine secretion; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:UniProtKB.::GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002513; P:tolerance induction to self antigen; IMP:UniProtKB.
98Q9URW6    430   YIE2_SCHPO SH3 domain-containing protein PJ69...560.00005     45.4     38     55GO:0030479; C:actin cortical patch; ISS:PomBase.
GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.
99Q5ZLR6    764   ARHG6_CHICK Rho guanine nucleotide exchange f...890.00005     45.4     29     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
100Q75DS3    443   HSE1_ASHGO Class E vacuolar protein-sorting m...600.00005     45.4     30     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
101Q75JD4    533   Y1676_DICDI SH3 and FCH domain-containing pro...520.00005     45.4     35     54
102P32793    468   YSC84_YEAST Protein YSC84 OS=Saccharomyces ce...560.00005     45.1     32     57GO:0030479; C:actin cortical patch; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD.
103O43150    1006   ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe...530.00005     45.4     34     58GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
104Q8AXV0    367   SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C...910.00006     45.1     31     48GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
105P43603    459   LSB3_YEAST LAS seventeen-binding protein 3 OS...560.00007     45.1     36     57GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051666; P:actin cortical patch localization; IMP:SGD.
106A7A261    459   LSB3_YEAS7 LAS seventeen-binding protein 3 OS...560.00007     45.1     36     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
107Q9QZM5    476   ABI1_RAT Abl interactor 1 OS=Rattus norvegicu...520.00008     44.7     42     60GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
108A2QW93    611   HSE1_ASPNC Class E vacuolar protein-sorting m...550.00008     44.7     35     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
109Q0CJU8    597   HSE1_ASPTN Class E vacuolar protein-sorting m...550.00008     44.7     35     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
110Q15052    776   ARHG6_HUMAN Rho guanine nucleotide exchange f...870.00008     44.7     30     53GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
111Q5T2T1    576   MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Ho...730.00009     44.7     38     55GO:0097025; C:MPP7-DLG1-LIN7 complex; IDA:BHF-UCL.::GO:0005923; C:tight junction; IDA:BHF-UCL.
GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0035591; F:signaling adaptor activity; NAS:BHF-UCL.
GO:0030010; P:establishment of cell polarity; TAS:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.::GO:0070830; P:tight junction assembly; IDA:BHF-UCL.
112Q8K4I3    771   ARHG6_MOUSE Rho guanine nucleotide exchange f...530.00009     44.7     38     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
113Q8CBW3    481   ABI1_MOUSE Abl interactor 1 OS=Mus musculus (...520.00009     44.7     42     60GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:MGI.
GO:0001756; P:somitogenesis; IMP:MGI.
114Q5R5W0    261   LASP1_PONAB LIM and SH3 domain protein 1 OS=P...550.00009     44.3     38     62GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
115Q14847    261   LASP1_HUMAN LIM and SH3 domain protein 1 OS=H...550.00009     44.3     38     62GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
116Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...530.0001     44.7     38     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
117Q3B7M5    260   LASP1_BOVIN LIM and SH3 domain protein 1 OS=B...550.0001     44.3     38     62GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
118Q61792    263   LASP1_MOUSE LIM and SH3 domain protein 1 OS=M...550.0001     44.3     38     62GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
119P51451    505   BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo...600.0001     44.3     45     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.
120Q91X43    789   SH319_MOUSE SH3 domain-containing protein 19 ...660.0002     43.9     30     55
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
121Q99MZ8    263   LASP1_RAT LIM and SH3 domain protein 1 OS=Rat...550.0001     43.9     38     62GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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