| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | P08487 | 1291 | PLCG1_BOVIN 1-phosphatidylinositol 4,5-bispho... | 54 | 0.024 | 37.7 | 31 | 52 | GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:AgBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB. | 332 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 44 | 0.21 | 35 | 39 | 55 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 333 | Q5ZJ00 | 468 | EM55_CHICK 55 kDa erythrocyte membrane protei... | 75 | 0.025 | 37.4 | 33 | 47 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 334 | Q5PYH5 | 827 | DLG1L_DANRE Discs large homolog 1-like protei... | 60 | 0.026 | 37.4 | 37 | 55 | GO:0016323; C:basolateral plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0030866; P:cortical actin cytoskeleton organization; ISS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0050808; P:synapse organization; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:UniProtKB. | 335 | Q0VBZ0 | 450 | CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ... | 54 | 0.026 | 37.4 | 31 | 61 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 336 | Q64434 | 451 | PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus m... | 53 | 0.026 | 37.4 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0060575; P:intestinal epithelial cell differentiation; IMP:UniProtKB.::GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; ISS:UniProtKB. | 337 | A3LXQ8 | 475 | HSE1_PICST Class E vacuolar protein-sorting m... | 77 | 0.027 | 37.4 | 32 | 49 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 338 | Q13882 | 451 | PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo ... | 52 | 0.027 | 37.4 | 33 | 48 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IDA:UniProtKB. | 339 | P00527 | 528 | YES_AVISY Tyrosine-protein kinase transformin... | 51 | 0.027 | 37.4 | 31 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 340 | P41241 | 450 | CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ... | 54 | 0.028 | 37.4 | 31 | 61 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC. | 341 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 118 | 0.028 | 37.4 | 28 | 42 | | | | | | | | | | | | | | | | | | | | | | 342 | P41239 | 450 | CSK_CHICK Tyrosine-protein kinase CSK OS=Gall... | 54 | 0.028 | 37.4 | 31 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 343 | Q2US45 | 1261 | MYO1_ASPOR Myosin-1 OS=Aspergillus oryzae (st... | 54 | 0.029 | 37.4 | 30 | 52 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 344 | Q9XYM0 | 271 | CRK_DROME Adapter molecule Crk OS=Drosophila ... | 70 | 0.03 | 37 | 24 | 49 | | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase. | | | | | | | | | | GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 345 | P32577 | 450 | CSK_RAT Tyrosine-protein kinase CSK OS=Rattus... | 54 | 0.03 | 37.4 | 31 | 61 | GO:0045121; C:membrane raft; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0034332; P:adherens junction organization; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IDA:RGD.::GO:0045779; P:negative regulation of bone resorption; IDA:RGD.::GO:0008285; P:negative regulation of cell proliferation; IDA:RGD.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IDA:RGD.::GO:0033673; P:negative regulation of kinase activity; IDA:RGD.::GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IDA:RGD.::GO:0050765; P:negative regulation of phagocytosis; IDA:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0060368; P:regulation of Fc receptor mediated stimulatory signaling pathway; IDA:RGD. | 346 | P41240 | 450 | CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo... | 54 | 0.03 | 37.4 | 31 | 61 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005886; C:plasma membrane; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 347 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 53 | 0.031 | 37.4 | 34 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 348 | Q9JLB2 | 675 | MPP5_MOUSE MAGUK p55 subfamily member 5 OS=Mu... | 44 | 0.031 | 37.4 | 43 | 52 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0043219; C:lateral loop; IDA:BHF-UCL.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032287; P:peripheral nervous system myelin maintenance; IMP:BHF-UCL.::GO:0035750; P:protein localization to myelin sheath abaxonal region; IMP:BHF-UCL. | 349 | Q8N3R9 | 675 | MPP5_HUMAN MAGUK p55 subfamily member 5 OS=Ho... | 44 | 0.032 | 37.4 | 43 | 52 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:BHF-UCL. | | | | | | | | | | GO:0070830; P:tight junction assembly; TAS:Reactome. | 350 | Q5RDQ2 | 675 | MPP5_PONAB MAGUK p55 subfamily member 5 OS=Po... | 44 | 0.033 | 37.4 | 43 | 52 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 351 | Q68F99 | 337 | STAC3_XENTR SH3 and cysteine-rich domain-cont... | 57 | 0.035 | 37 | 26 | 53 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 352 | O77774 | 392 | NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos... | 54 | 0.072 | 36.2 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB. | 353 | P38822 | 633 | BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere... | 84 | 0.038 | 37 | 33 | 46 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD. | 354 | A6H7G2 | 423 | DBNL_BOVIN Drebrin-like protein OS=Bos taurus... | 54 | 0.041 | 37 | 33 | 54 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 355 | Q5A895 | 498 | HSE1_CANAL Class E vacuolar protein-sorting m... | 52 | 0.042 | 37 | 33 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 356 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 57 | 0.042 | 36.6 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 357 | Q9P2A4 | 366 | ABI3_HUMAN ABI gene family member 3 OS=Homo s... | 57 | 0.043 | 36.6 | 35 | 49 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:MGI. | 358 | Q24210 | 898 | CSKP_DROME Peripheral plasma membrane protein... | 66 | 0.043 | 37 | 32 | 42 | GO:0031594; C:neuromuscular junction; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0061174; C:type I terminal button; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:FlyBase.::GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007163; P:establishment or maintenance of cell polarity; NAS:FlyBase.::GO:0040011; P:locomotion; IMP:BHF-UCL.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:BHF-UCL.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IDA:FlyBase.::GO:2000331; P:regulation of terminal button organization; IMP:BHF-UCL.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; NAS:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; NAS:FlyBase. | 359 | Q9JHL4 | 436 | DBNL_RAT Drebrin-like protein OS=Rattus norve... | 54 | 0.043 | 36.6 | 33 | 54 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB. | 360 | Q09014 | 390 | NCF1_MOUSE Neutrophil cytosol factor 1 OS=Mus... | 54 | 2.9 | 31.6 | 31 | 50 | GO:0005829; C:cytosol; TAS:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006968; P:cellular defense response; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0006691; P:leukotriene metabolic process; IMP:MGI.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:MGI.::GO:0070947; P:neutrophil mediated killing of fungus; IMP:MGI.::GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IMP:MGI.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; IMP:MGI.::GO:0001878; P:response to yeast; IMP:MGI.::GO:0042554; P:superoxide anion generation; IMP:MGI. | 361 | Q9UJU6 | 430 | DBNL_HUMAN Drebrin-like protein OS=Homo sapie... | 54 | 0.046 | 36.6 | 33 | 54 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0008047; F:enzyme activator activity; TAS:ProtInc. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB. |
