rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q557K0 | 450 | Y3509_DICDI TNF receptor-associated factor fa... | 294 | 0.00009 | 48.1 | 22 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 32 | Q2TBT8 | 240 | RN151_BOVIN RING finger protein 151 OS=Bos ta... | 124 | 0.00005 | 48.1 | 25 | 41 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 33 | Q91XL2 | 687 | LNX2_MOUSE Ligand of Numb protein X 2 OS=Mus ... | 112 | 0.00006 | 49.3 | 29 | 44 | | | | | | | | | | | GO:0030165; F:PDZ domain binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051260; P:protein homooligomerization; IDA:MGI. | 34 | Q865W2 | 486 | TRI50_PIG E3 ubiquitin-protein ligase TRIM50 ... | 85 | 0.0002 | 47 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 35 | Q9C6H3 | 313 | SINL2_ARATH E3 ubiquitin-protein ligase SINA-... | 136 | 0.0003 | 46.2 | 28 | 40 | GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 36 | P15919 | 1040 | RAG1_MOUSE V(D)J recombination-activating pro... | 122 | 0.0004 | 46.6 | 25 | 43 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; IMP:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:MGI.::GO:0070244; P:negative regulation of thymocyte apoptotic process; IMP:MGI.::GO:0002331; P:pre-B cell allelic exclusion; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; IMP:UniProtKB.::GO:0033151; P:V(D)J recombination; IMP:UniProtKB. | 37 | P39429 | 501 | TRAF2_MOUSE TNF receptor-associated factor 2 ... | 286 | 0.0006 | 45.8 | 22 | 42 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005174; F:CD40 receptor binding; IPI:BHF-UCL.::GO:0046625; F:sphingolipid binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; NAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0030163; P:protein catabolic process; IMP:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0051023; P:regulation of immunoglobulin secretion; IMP:MGI.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:UniProtKB. | 38 | Q867B5 | 1043 | RAG1_PIG V(D)J recombination-activating prote... | 122 | 0.0007 | 45.8 | 25 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 39 | Q91829 | 1045 | RAG1_XENLA V(D)J recombination-activating pro... | 123 | 0.0007 | 45.8 | 28 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 40 | Q7ZW16 | 318 | RNF41_DANRE E3 ubiquitin-protein ligase NRDP1... | 145 | 0.0007 | 45.1 | 25 | 42 | | | | | | | | | | | GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030318; P:melanocyte differentiation; IMP:ZFIN.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 41 | P24271 | 1041 | RAG1_CHICK V(D)J recombination-activating pro... | 122 | 0.0008 | 45.8 | 24 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 42 | P15918 | 1043 | RAG1_HUMAN V(D)J recombination-activating pro... | 107 | 0.0009 | 45.4 | 26 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 43 | Q86KX6 | 595 | Y2348_DICDI TNF receptor-associated factor fa... | 143 | 0.001 | 44.7 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 44 | Q54FB9 | 445 | Y0971_DICDI TNF receptor-associated factor fa... | 257 | 0.002 | 44.3 | 25 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 45 | Q922Y2 | 403 | TRI59_MOUSE Tripartite motif-containing prote... | 60 | 0.002 | 43.9 | 37 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 46 | Q1ZXR0 | 502 | Y8444_DICDI TNF receptor-associated factor fa... | 243 | 0.002 | 43.9 | 24 | 35 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro. | 47 | Q8IWR1 | 403 | TRI59_HUMAN Tripartite motif-containing prote... | 67 | 0.002 | 43.5 | 36 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 48 | Q55A66 | 1084 | Y2098_DICDI TNF receptor-associated factor fa... | 245 | 0.003 | 43.9 | 21 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 49 | Q6J2U6 | 229 | RN114_RAT RING finger protein 114 OS=Rattus n... | 122 | 0.003 | 42.7 | 26 | 39 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 50 | Q92021 | 609 | NF7B_XENLA Nuclear factor 7, brain OS=Xenopus... | 94 | 0.003 | 43.5 | 24 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | F6ZQ54 | 408 | TRI13_XENTR Tripartite motif containing 13 OS... | 59 | 0.003 | 43.1 | 42 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 52 | Q28GL3 | 416 | RNFT1_XENTR RING finger and transmembrane dom... | 33 | 0.003 | 43.1 | 52 | 70 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 53 | Q5FWL3 | 317 | RNF41_XENLA E3 ubiquitin-protein ligase NRDP1... | 145 | 0.004 | 42.7 | 25 | 41 | | | | | | | | | | | GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 54 | O60858 | 407 | TRI13_HUMAN E3 ubiquitin-protein ligase TRIM1... | 61 | 0.004 | 43.1 | 41 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0016239; P:positive regulation of macroautophagy; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0010332; P:response to gamma radiation; IEP:UniProtKB. | 55 | P19474 | 475 | RO52_HUMAN E3 ubiquitin-protein ligase TRIM21... | 54 | 0.004 | 43.1 | 33 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB. | 56 | P21192 | 770 | ACE2_YEAST Metallothionein expression activat... | 146 | 0.004 | 43.1 | 25 | 47 | GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:2001043; P:positive regulation of cytokinetic cell separation involved in cell cycle cytokinesis; IMP:SGD.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD. | 57 | Q8BH75 | 317 | RNF41_MOUSE E3 ubiquitin-protein ligase NRDP1... | 145 | 0.005 | 42.4 | 24 | 41 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 58 | Q5R7T5 | 317 | RNF41_PONAB E3 ubiquitin-protein ligase NRDP1... | 145 | 0.005 | 42.4 | 24 | 41 | | | | | | | | | | | GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 59 | Q9H4P4 | 317 | RNF41_HUMAN E3 ubiquitin-protein ligase NRDP1... | 145 | 0.005 | 42.4 | 24 | 41 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 60 | Q9CYB0 | 407 | TRI13_MOUSE E3 ubiquitin-protein ligase TRIM1... | 61 | 0.005 | 42.7 | 39 | 51 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0097038; C:perinuclear endoplasmic reticulum; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0016239; P:positive regulation of macroautophagy; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB. | 61 | Q86WT6 | 500 | TRI69_HUMAN Tripartite motif-containing prote... | 76 | 0.005 | 42.7 | 30 | 46 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. |